Rare Disease Trial Updates: July 2026
In July 2026, Trial Friend tracked 517 rare disease clinical trial updates across 122 conditions, including 3 FDA-related actions and 127 trial status changes, alongside enrollment updates and new trial site openings sourced from ClinicalTrials.gov and FDA announcements.
This is a permanent monthly archive. For the latest updates, see the live current events feed.
Major Updates: FDA Actions, Status Changes & Results
No longer enrolling new participants
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Now recruiting (was Active Not Recruiting)
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Now recruiting (was Active Not Recruiting)
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Now recruiting (was Enrolling By Invitation)
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Now recruiting (was Enrolling By Invitation)
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Status changed from Recruiting to Enrolling By Invitation
No longer enrolling new participants
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Now recruiting (was Enrolling By Invitation)
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The FDA granted orphan drug designation to betaine, developed by Cycle Pharmaceuticals Ltd., on 2026-07-17 for the treatment of homocystinuria. Orphan designation is an incentive for rare disease drug development, not an approval: it gives the sponsor tax credits, fee waivers, and 7 years of market exclusivity if the drug is eventually approved. It often signals that a company is committing to a full development program.
No longer enrolling new participants
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Now recruiting (was Active Not Recruiting)
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Now recruiting (was Active Not Recruiting)
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No longer enrolling new participants
Now recruiting (was Active Not Recruiting)
Status changed from Recruiting to Enrolling By Invitation
No longer enrolling new participants
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The U.S. Food and Drug Administration today issued a proposed rule that, if finalized, would create a streamlined registration pathway for distributed manufacturing establishments that operate as a single establishment using a “hub-and-spoke” model.
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Now recruiting (was Active Not Recruiting)
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The U.S. Food and Drug Administration today issued a supplemental approval for Casgevy (exagamglogene autotemcel) for patients aged 2 years and older with either sickle cell disease (SCD) with recurrent vaso-occlusive crises (VOCs) or transfusion-dependent β thalassemia (TDT).
No longer enrolling new participants
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Trial Site & Enrollment Activity
Added 1 new site: Herston, Australia
Added 6 new sites: Walnut Creek, California, Malvern, Australia, Sydney, Australia and 3 more
Added 1 new site: Richmond, Virginia
Added 3 new sites: Tampa, Florida, Nashville, Tennessee, Houston, Texas
Added 3 new sites: São Paulo, Brazil, São Paulo, Brazil, Sofia, Bulgaria
Eligibility criteria have been updated
Reduced from 30 to 28 sites
Added 3 new sites: Huntington Beach, California, Greenville, North Carolina, Raleigh, North Carolina
Added 12 new sites: South Brisbane, Australia, Sliven, Bulgaria, Smolyan, Bulgaria and 9 more
Added 4 new sites: Santiago, Chile, Acquaviva delle Fonti, Italy, Livorno, Italy and 1 more
Added 6 new sites: Los Angeles, California, Albury, Australia, Hurstville, Australia and 3 more
Eligibility criteria have been updated
Added 3 new sites: Mission Hills, California, Belo Horizonte, Brazil, Miraflores, Peru
Added 1 new site: Chicago, Illinois
Added 1 new site: Cincinnati, Ohio
Added 6 new sites: New York, New York, Porto Alegre, Brazil, Ribeirão Preto, Brazil and 3 more
Added 8 new sites: Baltimore, Maryland, Fortaleza, Brazil, Porto Alegre, Brazil and 5 more
Added 1 new site: Montreal, Canada
Reduced from 13 to 11 sites
Added 2 new sites: Los Angeles, California, Heidelberg, Australia
Added 9 new sites: Edmonton, Canada, Hamilton, Canada, Lille, France and 6 more
Added 3 new sites: Genk, Belgium, Jinan, China, Guangzhou, China
Added 12 new sites: Houston, Texas, Woolloongabba, Australia, Ribeirão Preto, Brazil and 9 more
Added 7 new sites: Columbus, Ohio, Córdoba, Argentina, Binhai, China and 4 more
Target enrollment increased from 1250 to 1750
Eligibility criteria have been updated
Added 6 new sites: Hefei, China, Chongqing, China, Guiyang, China and 3 more
Eligibility criteria have been updated
Added 10 new sites: Phoenix, Arizona, Aurora, Colorado, Baltimore, Maryland and 7 more
Added 1 new site: Hradec Králové, Czechia
Added 2 new sites: Cambridge, United Kingdom, Southampton, United Kingdom
Added 3 new sites: Paris, France, Utrecht, Netherlands, Madrid, Spain
Added 1 new site: Osaka, Japan
Added 6 new sites: Hefei, China, Chongqing, China, Guiyang, China and 3 more
Added 3 new sites: Paris, France, Florence, Italy, Târgu Mureş, Romania
Eligibility criteria have been updated
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment increased from 2 to 20
Added 4 new sites: Halle, Germany, Mainz, Germany, Bialystok, Poland and 1 more
Added 2 new sites: Randwick, Australia, Shatin, Hong Kong
Reduced from 32 to 29 sites
Eligibility criteria have been updated
Eligibility criteria have been updated
Expanded from 85 to 87 sites
Added 2 new sites: Lille, France, Paris, France
Added 1 new site: Busan, South Korea
Eligibility criteria have been updated
Added 9 new sites: Minneapolis, Minnesota, Cincinnati, Ohio, Aarhus, Denmark and 6 more
Added 1 new site: Roma, Italy
Added 1 new site: Charlotte, North Carolina
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 1 new site: Sacramento, California
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 2 new sites: Tampa, Florida, Manchester, United Kingdom
Added 1 new site: Charleston, South Carolina
Added 7 new sites: Chattanooga, Tennessee, Bydgoszcz, Poland, Poznan, Poland and 4 more
Added 1 new site: Kocaeli, Turkey (Türkiye)
Added 1 new site: Belgrade, Serbia
Expanded from 90 to 91 sites
Reduced from 124 to 120 sites
Moved from Phase 4 to Phase 3
Added 12 new sites: Ulm, Germany, Düsseldorf, Germany, Hamburg, Germany and 9 more
Target enrollment increased from 200 to 400
Added 1 new site: Coral Springs, Florida
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Shanghai, China
Added 6 new sites: Shenyang, China, Prague, Czechia, Cork, Ireland and 3 more
Eligibility criteria have been updated
Target enrollment decreased from 18 to 9
Eligibility criteria have been updated
Added 3 new sites: Houston, Texas, Catamarca, Argentina, Toronto, Canada
Added 3 new sites: Shanghai, China, Prague, Czechia, Modena, Italy
Added 9 new sites: Indianapolis, Indiana, New York, New York, Cincinnati, Ohio and 6 more
Added 3 new sites: Córdoba, Argentina, Camperdown, Australia, London, United Kingdom
Added 6 new sites: New Lambton Heights, Australia, Herston, Australia, Nedlands, Australia and 3 more
Added 19 new sites: Hialeah, Florida, Jacksonville, Florida, Orlando, Florida and 16 more
Added 3 new sites: Basingstoke, United Kingdom, Cardiff, United Kingdom, Nottingham, United Kingdom
Added 3 new sites: Birtinya, Australia, Dijon, France, Bunkyō City, Japan
Reduced from 63 to 60 sites
Added 1 new site: Hackensack, New Jersey
Added 12 new sites: Orange, California, Gainesville, Florida, Atlanta, Georgia and 9 more
Eligibility criteria have been updated
Added 6 new sites: Champaign, Illinois, Las Vegas, Nevada, Asheville, North Carolina and 3 more
Eligibility criteria have been updated
Added 4 new sites: Glendale, California, Greenville, North Carolina, McAllen, Texas and 1 more
Added 2 new sites: Reno, Nevada, Belfast, United Kingdom
Added 1 new site: Barcelona, Spain
Added 1 new site: Farmington, New Mexico
Added 5 new sites: Humble, Texas, San Miguel de Tucumán, Argentina, Pleven, Bulgaria and 2 more
Eligibility criteria have been updated
Added 2 new sites: Raleigh, North Carolina, Houston, Texas
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 2 new sites: Scottsdale, Arizona, Incheon, South Korea
Added 4 new sites: Shanghai, China, Beijing, China, Guangzhou, China and 1 more
Added 6 new sites: Loma Linda, California, Madera, California, Washington D.C., District of Columbia and 3 more
Added 9 new sites: Prague, Czechia, Essen, Germany, Hamburg, Germany and 6 more
Added 7 new sites: Orange, California, Kansas City, Kansas, Grand Rapids, Michigan and 4 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 10 new sites: Sofia, Bulgaria, Rüdersdorf, Germany, Himeji, Japan and 7 more
Eligibility criteria have been updated
Added 5 new sites: Himeji, Japan, Isehara, Japan, Sendai, Japan and 2 more
Added 2 new sites: Rozzano, Italy, Yamaguchi, Japan
Added 7 new sites: Birmingham, Alabama, Bogotá, Colombia, Medellín, Colombia and 4 more
Added 10 new sites: Córdoba, Argentina, Rosario, Argentina, São Paulo, Brazil and 7 more
Added 3 new sites: Tucson, Arizona, San Francisco, California, Ulm, Germany
Added 10 new sites: Sofia, Bulgaria, Rüdersdorf, Germany, Himeji, Japan and 7 more
Eligibility criteria have been updated
Added 10 new sites: Sofia, Bulgaria, Rüdersdorf, Germany, Himeji, Japan and 7 more
Eligibility criteria have been updated
Added 3 new sites: Ulm, Germany, Zabrze, Poland, Warsaw, Poland
Added 5 new sites: Himeji, Japan, Isehara, Japan, Sendai, Japan and 2 more
Added 5 new sites: Himeji, Japan, Isehara, Japan, Sendai, Japan and 2 more
Added 6 new sites: Loma Linda, California, Madera, California, Washington D.C., District of Columbia and 3 more
Added 1 new site: Calgary, Canada
Added 9 new sites: Prague, Czechia, Essen, Germany, Hamburg, Germany and 6 more
Added 7 new sites: Orange, California, Kansas City, Kansas, Grand Rapids, Michigan and 4 more
Eligibility criteria have been updated
Added 3 new sites: Lecce, Italy, Messina, Italy, Milan, Italy
Target enrollment increased from 160 to 240
Eligibility criteria have been updated
Added 1 new site: London, Canada
Added 1 new site: London, Canada
Added 1 new site: Seattle, Washington
Target enrollment increased from 2500 to 5000
Added 3 new sites: Guanzhou, China, Shenzhen, China, Nanning, China
Reduced from 56 to 47 sites
Added 4 new sites: Shanghai, China, Beijing, China, Guangzhou, China and 1 more
Added 1 new site: Pittsburgh, Pennsylvania
Eligibility criteria have been updated
Added 2 new sites: Philadelphia, Pennsylvania, Ankara, Turkey (Türkiye)
Eligibility criteria have been updated
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 1 new site: São Paulo, Brazil
Added 9 new sites: South Brisbane, Australia, Leuven, Belgium, Brussels, Belgium and 6 more
Added 2 new sites: South San Francisco, California, Petah Tikva, Israel
Added 5 new sites: Buenos Aires, Argentina, Hefei, China, Johor Bahru, Malaysia and 2 more
Added 8 new sites: Rochester, Minnesota, Ghent, Belgium, Toronto, Canada and 5 more
Eligibility criteria have been updated
Added 1 new site: Indianapolis, Indiana
Added 2 new sites: Miami, Florida, Miami Lakes, Florida
Added 2 new sites: Richmond, Virginia, Milan, Italy
Added 5 new sites: Buenos Aires, Argentina, Hefei, China, Johor Bahru, Malaysia and 2 more
Added 1 new site: Reno, Nevada
Added 1 new site: Miami, Florida
Eligibility criteria have been updated
Added 1 new site: Ufa, Russia
Reduced from 13 to 9 sites
Added 6 new sites: Aalen, Germany, Bogen, Germany, Dillingen Saar, Germany and 3 more
Added 2 new sites: Livingston, New Jersey, Lublin, Poland
Added 3 new sites: Mainz, Germany, Barcelona, Spain, Madrid, Spain
Added 5 new sites: Boca Raton, Florida, Clearwater, Florida, Indianapolis, Indiana and 2 more
Reduced from 102 to 71 sites
Eligibility criteria have been updated
Added 2 new sites: Lübeck, Germany, Neuruppin, Germany
Eligibility criteria have been updated
Added 10 new sites: Aurora, Colorado, Wellesley, Massachusetts, Dallas, Texas and 7 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Reduced from 40 to 33 sites
Added 1 new site: Boynton Beach, Florida
Reduced from 45 to 43 sites
Added 4 new sites: Shanghai, China, Beijing, China, Guangzhou, China and 1 more
Added 2 new sites: Boston, Massachusetts, Milwaukee, Wisconsin
Added 1 new site: Guiyang, China
Added 2 new sites: San Miguel de Tucumán, Argentina, London, United Kingdom
Added 14 new sites: Tampa, Florida, Indianapolis, Indiana, Iowa City, Iowa and 11 more
Added 9 new sites: Buenos Aires, Argentina, Belo Horizonte, Brazil, Campina Grande do Sul, Brazil and 6 more
Target enrollment decreased from 120 to 89
Added 1 new site: Hefei, China
Added 3 new sites: Doral, Florida, El Paso, Texas, Midlothian, Virginia
Added 1 new site: Oak Forest, Illinois
Added 1 new site: Reno, Nevada
Added 26 new sites: Bakersfield, California, Beverly Hills, California, Huntington Beach, California and 23 more
Added 1 new site: Paris, France
Added 9 new sites: Boca Raton, Florida, Livonia, Michigan, New Bern, North Carolina and 6 more
Eligibility criteria have been updated
Added 11 new sites: Brunswick, Georgia, Greensboro, North Carolina, Plovdiv, Bulgaria and 8 more
Eligibility criteria have been updated
Added 4 new sites: Buenos Aires, Argentina, Johor Bahru, Malaysia, Kuala Selangor, Malaysia and 1 more
Added 1 new site: Calgary, Canada
Target enrollment decreased from 300 to 211
Added 6 new sites: New Haven, Connecticut, Scarborough, Maine, Boston, Massachusetts and 3 more
Added 1 new site: Plymouth, Michigan
Added 2 new sites: Lille, France, Vandœuvre-lès-Nancy, France
Added 3 new sites: Chicago, Illinois, Rosario, Argentina, Lublin, Poland
Added 11 new sites: New Haven, Connecticut, Niigata, Japan, Kawasaki, Japan and 8 more
Added 2 new sites: New York, New York, Rozzano, Italy
Added 2 new sites: Münster, Germany, Tlalnepantla, Mexico
Target enrollment increased from 74 to 98
Eligibility criteria have been updated
Reduced from 8 to 6 sites
Target enrollment increased from 200 to 400
Eligibility criteria have been updated
Added 3 new sites: Heidelberg, Germany, Bari, Italy, Roma, Italy
Added 15 new sites: Bologna, Italy, Bologna, Italy, Bologna, Italy and 12 more
Reduced from 78 to 76 sites
Added 1 new site: Ulm, Germany
Added 1 new site: Málaga, Spain
Added 22 new sites: Birmingham, Alabama, Phoenix, Arizona, Scottsdale, Arizona and 19 more
Added 1 new site: Durham, North Carolina
Added 1 new site: Irvine, California
Added 1 new site: Adana, Turkey (Türkiye)
Target enrollment increased from 1343 to 1489
Added 1 new site: Richmond, Virginia
Reduced from 28 to 26 sites
Added 1 new site: Yangsan, South Korea
Added 4 new sites: Aurora, Colorado, Lake Success, New York, Edinburg, Texas and 1 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment decreased from 175 to 20
Eligibility criteria have been updated
Added 1 new site: Chevy Chase, Maryland
Added 1 new site: Chandigarh, India
Added 3 new sites: Duarte, California, Oakland, California, Baltimore, Maryland
Reduced from 28 to 26 sites
Added 1 new site: Adelaide, Australia
Added 5 new sites: Hefei, China, Xiamen, China, Wuhan, China and 2 more
Eligibility criteria have been updated
Added 5 new sites: Chongqing, China, Shenyang, China, Kolkata, India and 2 more
Added 1 new site: The Bronx, New York
Target enrollment increased from 319 to 429
Added 1 new site: Mainz, Germany
Added 3 new sites: Palo Alto, California, Houston, Texas, Toronto, Canada
Added 3 new sites: Santo André, Brazil, Lévis, Canada, Barcelona, Spain
Added 1 new site: Yangsan, South Korea
Added 4 new sites: Aurora, Colorado, Lake Success, New York, Edinburg, Texas and 1 more
Reduced from 50 to 43 sites
Added 5 new sites: Miami, Florida, Winter Park, Florida, Lansing, Michigan and 2 more
Added 23 new sites: Redwood City, California, Brandon, Florida, Miami, Florida and 20 more
Added 3 new sites: La Jolla, California, Nantes, France, Toulouse, France
Added 5 new sites: Chongqing, China, Shenyang, China, Kolkata, India and 2 more
Reduced from 36 to 27 sites
Added 1 new site: Los Angeles, California
Reduced from 9 to 6 sites
Added 3 new sites: Randwick, Australia, Madrid, Spain, Salamanca, Spain
Eligibility criteria have been updated
Added 3 new sites: Fairway, Kansas, Kansas City, Kansas, Westwood, Kansas
Added 1 new site: New York, New York
Added 1 new site: Headington, United Kingdom
Added 1 new site: New Orleans, Louisiana
Added 5 new sites: Los Angeles, California, Portland, Oregon, Riyadh, Saudi Arabia and 2 more
Added 2 new sites: München, Germany, Münster, Germany
Eligibility criteria have been updated
Added 6 new sites: Roeland Park, Kansas, Plovdiv, Bulgaria, Sofia, Bulgaria and 3 more
Added 1 new site: New York, New York
Added 18 new sites: New Lambton Heights, Australia, Box Hill, Australia, Strasbourg, France and 15 more
Added 1 new site: Natal, Brazil
Added 13 new sites: Alkmaar, Netherlands, Amsterdam, Netherlands, Breda, Netherlands and 10 more
Added 3 new sites: Kansas City, Kansas, Rochester, Minnesota, Madison, Wisconsin
Added 1 new site: Washington D.C., District of Columbia
Added 3 new sites: La Jolla, California, New York, New York, Cleveland, Ohio
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Qingdao, China
Eligibility criteria have been updated
Added 2 new sites: Seoul, South Korea, Seoul, South Korea
Added 1 new site: Konya, Turkey (Türkiye)
Added 1 new site: San Miguel de Tucumán, Argentina
Added 5 new sites: The Woodlands, Texas, Brussels, Belgium, Belo Horizonte,Minas Gerais, Brazil and 2 more
Added 3 new sites: Madera, California, Carroll, Iowa, Houston, Texas
Added 1 new site: Layton, Utah
Added 5 new sites: Santiago, Chile, Nagoya, Japan, Kamogawa, Japan and 2 more
Target enrollment decreased from 20 to 10
Added 2 new sites: Herston, Australia, Adelaide, Australia
Added 4 new sites: Iowa City, Iowa, Madrid, Spain, Málaga, Spain and 1 more
Added 6 new sites: San Diego, California, Hialeah, Florida, Morehead City, North Carolina and 3 more
Added 2 new sites: Merano, Italy, Milan, Italy
Added 1 new site: Lille, France
Added 10 new sites: Philadelphia, Pennsylvania, London, Canada, Ludwigshafen, Germany and 7 more
Added 8 new sites: Miami, Florida, Chicago, Illinois, Iowa City, Iowa and 5 more
Added 2 new sites: Philadelphia, Pennsylvania, Nuevo León, Mexico
Added 5 new sites: Chongqing, China, Shenyang, China, Kolkata, India and 2 more
Added 1 new site: Durham, North Carolina
Added 1 new site: Kansas City, Missouri
Reduced from 101 to 97 sites
Added 3 new sites: Salt Lake City, Utah, Bron, France, Paris, France
Added 14 new sites: Minneapolis, Minnesota, Durham, North Carolina, Cincinnati, Ohio and 11 more
Target enrollment increased from 60 to 160
Added 2 new sites: San Francisco, California, Tübingen, Germany
Added 1 new site: Port Charlotte, Florida
Added 3 new sites: Miami, Florida, Halle, Germany, Catania, Italy
Added 3 new sites: Jacksonville, Florida, Berlin, Germany, Madrid, Spain
Added 2 new sites: Paris, France, Jena, Germany
Reduced from 39 to 35 sites
Added 10 new sites: Wilmington, Delaware, Baltimore, Maryland, Cincinnati, Ohio and 7 more
Added 1 new site: Los Angeles, California
Reduced from 101 to 97 sites
Target enrollment decreased from 95 to 19
Added 1 new site: Fort Worth, Texas
Added 1 new site: Tokyo, Japan
Target enrollment decreased from 692 to 37
Added 2 new sites: New York, New York, New York, New York
Target enrollment increased from 184 to 224
Eligibility criteria have been updated
Added 1 new site: Los Angeles, California
Eligibility criteria have been updated
Added 1 new site: Los Angeles, California
Added 1 new site: Los Angeles, California
Target enrollment increased from 121 to 183
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Auckland, New Zealand
Added 2 new sites: San Diego, California, Miami, Florida
Added 2 new sites: Beijing, China, Hunan, China
Added 2 new sites: Colorado Springs, Colorado, Johnson City, Tennessee
Added 3 new sites: Rochester, Minnesota, Huntington, West Virginia, Coimbra, Portugal
Reduced from 101 to 97 sites
Added 4 new sites: Plantation, Florida, Tamarac, Florida, Bethesda, Maryland and 1 more
Added 2 new sites: Guangzhou, China, Yantai, China
Moved from N/A to Phase 1
Added 15 new sites: Garran, Australia, Anderlecht, Belgium, Turnhout, Belgium and 12 more
Added 17 new sites: Redwood City, California, Miami, Florida, Cincinnati, Ohio and 14 more
Added 3 new sites: Denver, North Carolina, Cincinnati, Ohio, Sugar Land, Texas
Added 5 new sites: Cullman, Alabama, Kansas City, Kansas, Middletown, New Jersey and 2 more
Added 1 new site: München, Germany
Added 8 new sites: Indianapolis, Indiana, Leuven, Belgium, Copenhagen, Denmark and 5 more
Reduced from 101 to 97 sites
Added 2 new sites: Guangzhou, China, Yantai, China
Added 1 new site: Hackensack, New Jersey
Target enrollment increased from 24 to 30
Eligibility criteria have been updated
Added 2 new sites: New York, New York, Westmead, Australia
Added 6 new sites: Jacksonville, Florida, Miami, Florida, Box Hill, Australia and 3 more
Added 1 new site: Columbus, Ohio
Added 3 new sites: Palo Alto, California, New York, New York, Westmead, Australia
Eligibility criteria have been updated
Added 1 new site: Poznan, Poland
Eligibility criteria have been updated
Added 1 new site: London, United Kingdom
Added 4 new sites: Clayton, Australia, Concord, Australia, Bari, Italy and 1 more
Eligibility criteria have been updated
Added 6 new sites: Orlando, Florida, New York, New York, Philadelphia, Pennsylvania and 3 more
Eligibility criteria have been updated
Added 6 new sites: San Miguel de Tucumán, Argentina, Buenos Aires, Argentina, Santa Fe, Argentina and 3 more
Eligibility criteria have been updated
Added 7 new sites: Kansas City, Kansas, Baltimore, Maryland, Salt Lake City, Utah and 4 more
Added 2 new sites: Salt Lake City, Utah, Warsaw, Poland
Added 2 new sites: Mount Kisco, New York, Beaverton, Oregon
Added 2 new sites: Clayton, Australia, Cambridge, United Kingdom
Added 2 new sites: Houston, Texas, Houston, Texas
Added 2 new sites: Catania, Italy, Padua, Italy
Added 1 new site: Chicago, Illinois
Added 1 new site: Tianjin, China
Added 1 new site: Miami, Florida
Eligibility criteria have been updated
Added 4 new sites: Burbank, California, Walnut Creek, California, Lenexa, Kansas and 1 more
Added 2 new sites: Irvine, California, Durham, North Carolina
Added 1 new site: Austin, Texas
Reduced from 174 to 152 sites
Added 2 new sites: Guangzhou, China, Yantai, China
Added 2 new sites: Durham, North Carolina, Portland, Oregon
Added 1 new site: Miami, Florida
Eligibility criteria have been updated
Target enrollment increased from 100 to 210
Added 13 new sites: Chicago, Illinois, Dijon, France, Marseille, France and 10 more
Added 2 new sites: New Haven, Connecticut, New Delhi, India
Eligibility criteria have been updated
Reduced from 61 to 58 sites
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 4 new sites: Philadelphia, Pennsylvania, Curitiba, Brazil, Porto Alegre, Brazil and 1 more
Target enrollment increased from 150 to 200
Eligibility criteria have been updated
Added 2 new sites: New York, New York, Westmead, Australia
Added 1 new site: Lebanon, New Hampshire
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 5 new sites: Marseille, France, Marseille, France, Nantes, France and 2 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 2 new sites: Tampa, Florida, Milan, Italy
Added 40 new sites: Beijing, China, Beijing, China, Beijing, China and 37 more
Added 3 new sites: CABA, Argentina, Aarhus, Denmark, A Coruña, Spain
Added 2 new sites: Fredericton, Canada, Saskatoon, Canada
Added 2 new sites: Milan, Italy, Umeå, Sweden
Added 1 new site: Boston, Massachusetts
Added 1 new site: Würzburg, Germany
Added 1 new site: Baltimore, Maryland
Added 1 new site: Stockholm, Sweden