Rare Disease Trial Updates: July 2026
In July 2026, Trial Friend tracked 873 rare disease clinical trial updates across 144 conditions, including 8 FDA-related actions and 217 trial status changes, alongside enrollment updates and new trial site openings sourced from ClinicalTrials.gov and FDA announcements.
This is a permanent monthly archive. For the latest updates, see the live current events feed.
Major Updates: FDA Actions, Status Changes & Results
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FDA today licensed Ezplaz Freeze Dried Plasma (FDP), making it the first freeze-dried plasma product licensed for use in the United States. Ezplaz is intended for transfusion in adult patients who need plasma and for whom other plasma products are not available.
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The U.S. Food and Drug Administration today announced the first manufacturer selected for the Technology-Enabled Meaningful Patient Outcomes (TEMPO) for Digital Health Devices Pilot.
The U.S. Food and Drug Administration today announced two actions targeting petroleum-based color additives in food, continuing the agency’s broader efforts to Make America Healthy Again.
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The U.S. Food and Drug Administration approved Lipfendra (enlicitide), the first oral inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), as an adjunct to diet and exercise to reduce low-density lipoprotein cholesterol (LDL-C), or “bad” cholesterol, in adults with hypercholesterolemi
The FDA granted orphan drug designation to betaine, developed by Cycle Pharmaceuticals Ltd., on 2026-07-17 for the treatment of homocystinuria. Orphan designation is an incentive for rare disease drug development, not an approval: it gives the sponsor tax credits, fee waivers, and 7 years of market exclusivity if the drug is eventually approved. It often signals that a company is committing to a full development program.
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The FDA today issued an Emergency Use Authorization (EUA) for Ivermectin Liquid for Horses (ivermectin oral solution) for the short-term prevention of New World screwworm (NWS) infestations (myiasis) in horses when administered within 24 hours of birth or at the time of initial wound care.
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The U.S. Food and Drug Administration today issued a proposed rule that, if finalized, would create a streamlined registration pathway for distributed manufacturing establishments that operate as a single establishment using a “hub-and-spoke” model.
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The U.S. Food and Drug Administration today issued a supplemental approval for Casgevy (exagamglogene autotemcel) for patients aged 2 years and older with either sickle cell disease (SCD) with recurrent vaso-occlusive crises (VOCs) or transfusion-dependent β thalassemia (TDT).
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Trial Site & Enrollment Activity
Added 1 new site: Herston, Australia
Added 6 new sites: Walnut Creek, California, Malvern, Australia, Sydney, Australia and 3 more
Added 1 new site: Richmond, Virginia
Added 1 new site: Phoenix, Arizona
Added 3 new sites: Tampa, Florida, Nashville, Tennessee, Houston, Texas
Added 3 new sites: São Paulo, Brazil, São Paulo, Brazil, Sofia, Bulgaria
Eligibility criteria have been updated
Reduced from 30 to 28 sites
Added 3 new sites: Huntington Beach, California, Greenville, North Carolina, Raleigh, North Carolina
Added 12 new sites: South Brisbane, Australia, Sliven, Bulgaria, Smolyan, Bulgaria and 9 more
Added 4 new sites: Santiago, Chile, Acquaviva delle Fonti, Italy, Livorno, Italy and 1 more
Added 6 new sites: Los Angeles, California, Albury, Australia, Hurstville, Australia and 3 more
Eligibility criteria have been updated
Target enrollment increased from 40 to 64
Added 3 new sites: Mission Hills, California, Belo Horizonte, Brazil, Miraflores, Peru
Eligibility criteria have been updated
Target enrollment increased from 1 to 15
Reduced from 323 to 242 sites
Eligibility criteria have been updated
Target enrollment increased from 40 to 64
Eligibility criteria have been updated
Target enrollment increased from 1978 to 5386
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 27 new sites: New Haven, Connecticut, Bradenton, Florida, St. Petersburg, Florida and 24 more
Added 6 new sites: La Jolla, California, San Francisco, California, Minneapolis, Minnesota and 3 more
Eligibility criteria have been updated
Added 25 new sites: Palo Alto, California, Chicago, Illinois, São Paulo, Brazil and 22 more
Eligibility criteria have been updated
Added 1 new site: Tucson, Arizona
Added 1 new site: Chicago, Illinois
Eligibility criteria have been updated
Added 1 new site: Cincinnati, Ohio
Added 6 new sites: New York, New York, Porto Alegre, Brazil, Ribeirão Preto, Brazil and 3 more
Added 8 new sites: Baltimore, Maryland, Fortaleza, Brazil, Porto Alegre, Brazil and 5 more
Moved from Phase 2 to N/A
Added 3 new sites: Indianapolis, Indiana, Rochester, Minnesota, Chesterfield, Missouri
Eligibility criteria have been updated
Added 12 new sites: Ulm, Germany, Düsseldorf, Germany, Hamburg, Germany and 9 more
Added 1 new site: Reims, France
Added 1 new site: Montreal, Canada
Reduced from 13 to 11 sites
Added 2 new sites: Chicago, Illinois, The Bronx, New York
Added 2 new sites: Los Angeles, California, Heidelberg, Australia
Added 9 new sites: Edmonton, Canada, Hamilton, Canada, Lille, France and 6 more
Added 3 new sites: Genk, Belgium, Jinan, China, Guangzhou, China
Added 12 new sites: Houston, Texas, Woolloongabba, Australia, Ribeirão Preto, Brazil and 9 more
Added 7 new sites: Columbus, Ohio, Córdoba, Argentina, Binhai, China and 4 more
Target enrollment increased from 1250 to 1750
Eligibility criteria have been updated
Added 6 new sites: Hefei, China, Chongqing, China, Guiyang, China and 3 more
Eligibility criteria have been updated
Added 10 new sites: Phoenix, Arizona, Aurora, Colorado, Baltimore, Maryland and 7 more
Added 1 new site: Hradec Králové, Czechia
Added 2 new sites: Cambridge, United Kingdom, Southampton, United Kingdom
Added 7 new sites: Charleston, South Carolina, Nashville, Tennessee, Vienna, Austria and 4 more
Eligibility criteria have been updated
Added 1 new site: Seattle, Washington
Added 3 new sites: Paris, France, Utrecht, Netherlands, Madrid, Spain
Added 1 new site: Osaka, Japan
Eligibility criteria have been updated
Added 6 new sites: Hefei, China, Chongqing, China, Guiyang, China and 3 more
Added 3 new sites: Paris, France, Florence, Italy, Târgu Mureş, Romania
Added 7 new sites: Columbus, Ohio, Córdoba, Argentina, Binhai, China and 4 more
Target enrollment increased from 1250 to 1750
Eligibility criteria have been updated
Eligibility criteria have been updated
Eligibility criteria have been updated
Eligibility criteria have been updated
Reduced from 36 to 26 sites
Eligibility criteria have been updated
Target enrollment increased from 2 to 20
Added 4 new sites: Halle, Germany, Mainz, Germany, Bialystok, Poland and 1 more
Added 2 new sites: Randwick, Australia, Shatin, Hong Kong
Added 1 new site: San Francisco, California
Reduced from 32 to 29 sites
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment increased from 130 to 440
Eligibility criteria have been updated
Target enrollment increased from 32 to 40
Eligibility criteria have been updated
Expanded from 85 to 87 sites
Reduced from 44 to 42 sites
Added 5 new sites: New York, New York, Toronto, Canada, Halle, Germany and 2 more
Added 2 new sites: Lille, France, Paris, France
Added 1 new site: Busan, South Korea
Reduced from 36 to 26 sites
Reduced from 36 to 26 sites
Eligibility criteria have been updated
Added 9 new sites: Minneapolis, Minnesota, Cincinnati, Ohio, Aarhus, Denmark and 6 more
Added 1 new site: Roma, Italy
Added 1 new site: Charlotte, North Carolina
Added 5 new sites: New York, New York, Toronto, Canada, Halle, Germany and 2 more
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 1 new site: Sacramento, California
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 2 new sites: Tampa, Florida, Manchester, United Kingdom
Added 1 new site: Charleston, South Carolina
Added 1 new site: Busan, South Korea
Eligibility criteria have been updated
Added 7 new sites: Chattanooga, Tennessee, Bydgoszcz, Poland, Poznan, Poland and 4 more
Added 1 new site: Kocaeli, Turkey (Türkiye)
Added 1 new site: Belgrade, Serbia
Expanded from 90 to 91 sites
Reduced from 124 to 120 sites
Moved from Phase 4 to Phase 3
Added 9 new sites: Los Angeles, California, Debrecen, Hungary, Lodz, Poland and 6 more
Added 12 new sites: Ulm, Germany, Düsseldorf, Germany, Hamburg, Germany and 9 more
Eligibility criteria have been updated
Target enrollment increased from 200 to 400
Added 1 new site: Coral Springs, Florida
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Shanghai, China
Added 6 new sites: Shenyang, China, Prague, Czechia, Cork, Ireland and 3 more
Eligibility criteria have been updated
Target enrollment decreased from 18 to 9
Eligibility criteria have been updated
Added 1 new site: São Paulo, Brazil
Added 3 new sites: Houston, Texas, Catamarca, Argentina, Toronto, Canada
Added 3 new sites: Shanghai, China, Prague, Czechia, Modena, Italy
Added 9 new sites: Indianapolis, Indiana, New York, New York, Cincinnati, Ohio and 6 more
Added 3 new sites: Córdoba, Argentina, Camperdown, Australia, London, United Kingdom
Added 6 new sites: New Lambton Heights, Australia, Herston, Australia, Nedlands, Australia and 3 more
Added 19 new sites: Hialeah, Florida, Jacksonville, Florida, Orlando, Florida and 16 more
Added 2 new sites: Salt Lake City, Utah, Johannesburg, South Africa
Added 9 new sites: Lubbock, Texas, Jena, Germany, Gdansk, Poland and 6 more
Added 4 new sites: Denver, Colorado, Candiolo, Italy, Badalona, Spain and 1 more
Eligibility criteria have been updated
Added 1 new site: Charlotte, North Carolina
Added 3 new sites: Iowa City, Iowa, St Louis, Missouri, Columbus, Ohio
Reduced from 7 to 3 sites
Added 3 new sites: Basingstoke, United Kingdom, Cardiff, United Kingdom, Nottingham, United Kingdom
Added 2 new sites: Nanchang, China, Tianjin, China
Added 3 new sites: New Orleans, Louisiana, Neptune City, New Jersey, Edmonton, Canada
Eligibility criteria have been updated
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 11 new sites: Chongqing, China, Guangzhou, China, Kunming, China and 8 more
Added 2 new sites: New York, New York, Philadelphia, Pennsylvania
Added 2 new sites: Copenhagen, Denmark, Tel Aviv, Israel
Eligibility criteria have been updated
Added 1 new site: Irvine, California
Eligibility criteria have been updated
Added 3 new sites: Birtinya, Australia, Dijon, France, Bunkyō City, Japan
Added 1 new site: Edmonton, Canada
Added 1 new site: New York, New York
Reduced from 63 to 60 sites
Added 2 new sites: Bangalore, India, Patna, India
Added 5 new sites: The Woodlands, Texas, Cholet, France, Le Mans, France and 2 more
Added 1 new site: Hackensack, New Jersey
Added 12 new sites: Orange, California, Gainesville, Florida, Atlanta, Georgia and 9 more
Eligibility criteria have been updated
Added 2 new sites: Orland Park, Illinois, Morgantown, West Virginia
Added 6 new sites: Champaign, Illinois, Las Vegas, Nevada, Asheville, North Carolina and 3 more
Eligibility criteria have been updated
Added 4 new sites: Glendale, California, Greenville, North Carolina, McAllen, Texas and 1 more
Added 2 new sites: Reno, Nevada, Belfast, United Kingdom
Added 1 new site: Barcelona, Spain
Added 1 new site: Farmington, New Mexico
Added 5 new sites: Humble, Texas, San Miguel de Tucumán, Argentina, Pleven, Bulgaria and 2 more
Eligibility criteria have been updated
Target enrollment decreased from 10 to 2
Added 2 new sites: Raleigh, North Carolina, Houston, Texas
Added 5 new sites: New York, New York, Toronto, Canada, Halle, Germany and 2 more
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 2 new sites: Scottsdale, Arizona, Incheon, South Korea
Added 19 new sites: Oklahoma City, Oklahoma, Québec, Canada, Québec, Canada and 16 more
Added 7 new sites: Evergreen Park, Illinois, Marksville, Louisiana, Slidell, Louisiana and 4 more
Moved from Phase 2 to N/A
Target enrollment increased from 50 to 80
Eligibility criteria have been updated
Reduced from 252 to 242 sites
Added 99 new sites: San Jose, California, Colorado Springs, Colorado, La Plata, Argentina and 96 more
Target enrollment decreased from 450 to 360
Eligibility criteria have been updated
Added 1 new site: Los Angeles, California
Added 4 new sites: Shanghai, China, Beijing, China, Guangzhou, China and 1 more
Added 6 new sites: Loma Linda, California, Madera, California, Washington D.C., District of Columbia and 3 more
Added 9 new sites: Prague, Czechia, Essen, Germany, Hamburg, Germany and 6 more
Added 7 new sites: Orange, California, Kansas City, Kansas, Grand Rapids, Michigan and 4 more
Eligibility criteria have been updated
Added 52 new sites: Palo Alto, California, San Francisco, California, Aurora, Colorado and 49 more
Eligibility criteria have been updated
Added 10 new sites: Sofia, Bulgaria, Rüdersdorf, Germany, Himeji, Japan and 7 more
Eligibility criteria have been updated
Added 5 new sites: Himeji, Japan, Isehara, Japan, Sendai, Japan and 2 more
Added 2 new sites: Rozzano, Italy, Yamaguchi, Japan
Added 7 new sites: Birmingham, Alabama, Bogotá, Colombia, Medellín, Colombia and 4 more
Added 10 new sites: Córdoba, Argentina, Rosario, Argentina, São Paulo, Brazil and 7 more
Reduced from 66 to 50 sites
Added 1 new site: Cairo, Egypt
Eligibility criteria have been updated
Added 1 new site: Vancouver, Canada
Eligibility criteria have been updated
Moved from Phase 1, Phase 2 to Phase 1
Added 4 new sites: Rochester, Minnesota, Pittsburgh, Pennsylvania, Milan, Italy and 1 more
Target enrollment increased from 600 to 2500
Added 3 new sites: Tucson, Arizona, San Francisco, California, Ulm, Germany
Added 1 new site: Chicago, Illinois
Added 1 new site: Buenos Aires, Argentina
Eligibility criteria have been updated
Added 6 new sites: Denver, Colorado, Clayton, Australia, Heidelberg, Australia and 3 more
Eligibility criteria have been updated
Reduced from 47 to 45 sites
Added 10 new sites: Sofia, Bulgaria, Rüdersdorf, Germany, Himeji, Japan and 7 more
Eligibility criteria have been updated
Added 10 new sites: Sofia, Bulgaria, Rüdersdorf, Germany, Himeji, Japan and 7 more
Eligibility criteria have been updated
Added 3 new sites: Ulm, Germany, Zabrze, Poland, Warsaw, Poland
Added 5 new sites: Himeji, Japan, Isehara, Japan, Sendai, Japan and 2 more
Added 5 new sites: Himeji, Japan, Isehara, Japan, Sendai, Japan and 2 more
Added 6 new sites: Loma Linda, California, Madera, California, Washington D.C., District of Columbia and 3 more
Added 1 new site: Calgary, Canada
Added 9 new sites: Prague, Czechia, Essen, Germany, Hamburg, Germany and 6 more
Added 7 new sites: Orange, California, Kansas City, Kansas, Grand Rapids, Michigan and 4 more
Eligibility criteria have been updated
Added 3 new sites: Lecce, Italy, Messina, Italy, Milan, Italy
Eligibility criteria have been updated
Target enrollment increased from 160 to 240
Eligibility criteria have been updated
Added 1 new site: London, Canada
Added 1 new site: London, Canada
Added 1 new site: Seattle, Washington
Added 5 new sites: Dallas, Texas, Dallas, Texas, Dallas, Texas and 2 more
Target enrollment increased from 2500 to 5000
Added 3 new sites: Guanzhou, China, Shenzhen, China, Nanning, China
Reduced from 56 to 47 sites
Added 4 new sites: Shanghai, China, Beijing, China, Guangzhou, China and 1 more
Added 1 new site: Pittsburgh, Pennsylvania
Eligibility criteria have been updated
Added 2 new sites: Philadelphia, Pennsylvania, Ankara, Turkey (Türkiye)
Added 2 new sites: Omaha, Nebraska, Madison, Wisconsin
Eligibility criteria have been updated
Added 3 new sites: Gilbert, Arizona, San Francisco, California, New York, New York
Eligibility criteria have been updated
Added 1 new site: Baltimore, Maryland
Added 1 new site: São Paulo, Brazil
Added 9 new sites: South Brisbane, Australia, Leuven, Belgium, Brussels, Belgium and 6 more
Added 2 new sites: South San Francisco, California, Petah Tikva, Israel
Added 5 new sites: Buenos Aires, Argentina, Hefei, China, Johor Bahru, Malaysia and 2 more
Added 8 new sites: Rochester, Minnesota, Ghent, Belgium, Toronto, Canada and 5 more
Eligibility criteria have been updated
Added 1 new site: Indianapolis, Indiana
Added 2 new sites: Miami, Florida, Miami Lakes, Florida
Added 2 new sites: Richmond, Virginia, Milan, Italy
Added 5 new sites: Buenos Aires, Argentina, Hefei, China, Johor Bahru, Malaysia and 2 more
Added 1 new site: Chandigarh, India
Added 1 new site: Reno, Nevada
Added 1 new site: Miami, Florida
Eligibility criteria have been updated
Added 1 new site: Ufa, Russia
Reduced from 13 to 9 sites
Added 6 new sites: Aalen, Germany, Bogen, Germany, Dillingen Saar, Germany and 3 more
Added 2 new sites: Livingston, New Jersey, Lublin, Poland
Added 3 new sites: Mainz, Germany, Barcelona, Spain, Madrid, Spain
Added 5 new sites: Boca Raton, Florida, Clearwater, Florida, Indianapolis, Indiana and 2 more
Added 1 new site: Málaga, Spain
Reduced from 102 to 71 sites
Eligibility criteria have been updated
Added 2 new sites: Lübeck, Germany, Neuruppin, Germany
Eligibility criteria have been updated
Added 10 new sites: Aurora, Colorado, Wellesley, Massachusetts, Dallas, Texas and 7 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Reduced from 40 to 33 sites
Added 1 new site: Boynton Beach, Florida
Reduced from 45 to 43 sites
Added 4 new sites: Shanghai, China, Beijing, China, Guangzhou, China and 1 more
Added 2 new sites: Boston, Massachusetts, Milwaukee, Wisconsin
Added 2 new sites: Porto Alegre, Brazil, Mexico City, Mexico
Added 52 new sites: Palo Alto, California, San Francisco, California, Aurora, Colorado and 49 more
Added 1 new site: Guiyang, China
Added 1 new site: Toronto, Canada
Added 2 new sites: San Miguel de Tucumán, Argentina, London, United Kingdom
Added 14 new sites: Tampa, Florida, Indianapolis, Indiana, Iowa City, Iowa and 11 more
Added 9 new sites: Buenos Aires, Argentina, Belo Horizonte, Brazil, Campina Grande do Sul, Brazil and 6 more
Added 2 new sites: Houston, Texas, Houston, Texas
Added 15 new sites: Rochester, Minnesota, Columbus, Ohio, Buenos Aires, Argentina and 12 more
Added 68 new sites: Graz, Austria, Krems, Austria, Leoben, Austria and 65 more
Eligibility criteria have been updated
Added 2 new sites: San Francisco, California, Boston, Massachusetts
Eligibility criteria have been updated
Added 7 new sites: Birmingham, Alabama, Denver, Colorado, St Louis, Missouri and 4 more
Target enrollment increased from 248 to 315
Eligibility criteria have been updated
Added 3 new sites: Randwick, Australia, Madrid, Spain, Salamanca, Spain
Added 6 new sites: Philadelphia, Pennsylvania, Dallas, Texas, Tübingen, Germany and 3 more
Added 1 new site: Stony Brook, New York
Added 1 new site: Charlotte, North Carolina
Added 1 new site: Saint Hobart, Australia
Target enrollment decreased from 27 to 1
Eligibility criteria have been updated
Added 5 new sites: Mobile, Alabama, Portland, Oregon, Lubbock, Texas and 2 more
Added 1 new site: Jacksonville, Florida
Added 11 new sites: Quimper, France, Lyon, France, Marseille, France and 8 more
Added 69 new sites: Tampa, Florida, Atlanta, Georgia, Chicago, Illinois and 66 more
Eligibility criteria have been updated
Added 1 new site: Shanghai, China
Eligibility criteria have been updated
Target enrollment decreased from 120 to 89
Added 1 new site: Hefei, China
Added 3 new sites: Doral, Florida, El Paso, Texas, Midlothian, Virginia
Added 1 new site: Oak Forest, Illinois
Added 1 new site: Reno, Nevada
Added 26 new sites: Bakersfield, California, Beverly Hills, California, Huntington Beach, California and 23 more
Added 1 new site: Paris, France
Added 9 new sites: Boca Raton, Florida, Livonia, Michigan, New Bern, North Carolina and 6 more
Eligibility criteria have been updated
Added 11 new sites: Brunswick, Georgia, Greensboro, North Carolina, Plovdiv, Bulgaria and 8 more
Eligibility criteria have been updated
Target enrollment increased from 150 to 300
Added 4 new sites: Buenos Aires, Argentina, Johor Bahru, Malaysia, Kuala Selangor, Malaysia and 1 more
Added 1 new site: Calgary, Canada
Added 4 new sites: New Haven, Connecticut, DeSoto, Texas, Houston, Texas and 1 more
Reduced from 59 to 52 sites
Added 8 new sites: Lanzhou, China, Guangzhou, China, Shenzhen, China and 5 more
Added 1 new site: Miami, Florida
Target enrollment increased from 30 to 45
Eligibility criteria have been updated
Added 11 new sites: Changchun, China, Changsha, China, Chongqing, China and 8 more
Target enrollment decreased from 300 to 211
Added 1 new site: Montreal, Canada
Eligibility criteria have been updated
Added 6 new sites: New Haven, Connecticut, Scarborough, Maine, Boston, Massachusetts and 3 more
Added 1 new site: Plymouth, Michigan
Added 2 new sites: Lille, France, Vandœuvre-lès-Nancy, France
Added 3 new sites: Chicago, Illinois, Rosario, Argentina, Lublin, Poland
Added 11 new sites: New Haven, Connecticut, Niigata, Japan, Kawasaki, Japan and 8 more
Added 2 new sites: New York, New York, Rozzano, Italy
Added 2 new sites: Münster, Germany, Tlalnepantla, Mexico
Target enrollment decreased from 692 to 37
Added 1 new site: Miami, Florida
Eligibility criteria have been updated
Added 3 new sites: Chicago, Illinois, Rosario, Argentina, Lublin, Poland
Eligibility criteria have been updated
Added 2 new sites: Chapel Hill, North Carolina, Erlangen, Germany
Added 1 new site: Boca Raton, Florida
Added 1 new site: Miami Beach, Florida
Target enrollment increased from 74 to 98
Eligibility criteria have been updated
Reduced from 8 to 6 sites
Target enrollment increased from 200 to 400
Eligibility criteria have been updated
Added 3 new sites: Heidelberg, Germany, Bari, Italy, Roma, Italy
Added 15 new sites: Bologna, Italy, Bologna, Italy, Bologna, Italy and 12 more
Reduced from 78 to 76 sites
Added 1 new site: Ulm, Germany
Added 1 new site: Málaga, Spain
Added 22 new sites: Birmingham, Alabama, Phoenix, Arizona, Scottsdale, Arizona and 19 more
Added 1 new site: Durham, North Carolina
Added 1 new site: Irvine, California
Added 1 new site: Adana, Turkey (Türkiye)
Target enrollment increased from 1343 to 1489
Added 1 new site: Richmond, Virginia
Reduced from 28 to 26 sites
Added 1 new site: Yangsan, South Korea
Added 4 new sites: Aurora, Colorado, Lake Success, New York, Edinburg, Texas and 1 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment decreased from 20 to 10
Eligibility criteria have been updated
Target enrollment decreased from 175 to 20
Eligibility criteria have been updated
Added 15 new sites: Bologna, Italy, Bologna, Italy, Bologna, Italy and 12 more
Added 1 new site: Chevy Chase, Maryland
Added 1 new site: Chandigarh, India
Added 3 new sites: Duarte, California, Oakland, California, Baltimore, Maryland
Reduced from 28 to 26 sites
Reduced from 86 to 72 sites
Added 1 new site: Adelaide, Australia
Added 5 new sites: Hefei, China, Xiamen, China, Wuhan, China and 2 more
Eligibility criteria have been updated
Added 5 new sites: Chongqing, China, Shenyang, China, Kolkata, India and 2 more
Added 1 new site: The Bronx, New York
Target enrollment increased from 319 to 429
Added 1 new site: Mainz, Germany
Added 3 new sites: Palo Alto, California, Houston, Texas, Toronto, Canada
Added 3 new sites: Santo André, Brazil, Lévis, Canada, Barcelona, Spain
Added 1 new site: Yangsan, South Korea
Added 4 new sites: Aurora, Colorado, Lake Success, New York, Edinburg, Texas and 1 more
Reduced from 50 to 43 sites
Added 5 new sites: Miami, Florida, Winter Park, Florida, Lansing, Michigan and 2 more
Added 23 new sites: Redwood City, California, Brandon, Florida, Miami, Florida and 20 more
Added 3 new sites: La Jolla, California, Nantes, France, Toulouse, France
Added 5 new sites: Chongqing, China, Shenyang, China, Kolkata, India and 2 more
Reduced from 36 to 27 sites
Added 1 new site: Boston, Massachusetts
Added 1 new site: Los Angeles, California
Reduced from 9 to 6 sites
Added 3 new sites: Randwick, Australia, Madrid, Spain, Salamanca, Spain
Eligibility criteria have been updated
Added 3 new sites: Fairway, Kansas, Kansas City, Kansas, Westwood, Kansas
Added 3 new sites: Santo André, Brazil, Lévis, Canada, Barcelona, Spain
Added 1 new site: New York, New York
Added 1 new site: Headington, United Kingdom
Added 1 new site: New Orleans, Louisiana
Added 5 new sites: Los Angeles, California, Portland, Oregon, Riyadh, Saudi Arabia and 2 more
Added 2 new sites: München, Germany, Münster, Germany
Added 1 new site: Tokyo, Japan
Eligibility criteria have been updated
Added 4 new sites: CABA, Argentina, Córdoba, Argentina, Curitiba, Brazil and 1 more
Added 6 new sites: Roeland Park, Kansas, Plovdiv, Bulgaria, Sofia, Bulgaria and 3 more
Added 1 new site: New York, New York
Added 18 new sites: New Lambton Heights, Australia, Box Hill, Australia, Strasbourg, France and 15 more
Eligibility criteria have been updated
Added 1 new site: Natal, Brazil
Added 13 new sites: Alkmaar, Netherlands, Amsterdam, Netherlands, Breda, Netherlands and 10 more
Added 3 new sites: Kansas City, Kansas, Rochester, Minnesota, Madison, Wisconsin
Added 1 new site: Washington D.C., District of Columbia
Added 3 new sites: La Jolla, California, New York, New York, Cleveland, Ohio
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Westerville, Ohio
Added 1 new site: Qingdao, China
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Barakaldo, Spain
Added 2 new sites: Seoul, South Korea, Seoul, South Korea
Added 1 new site: Konya, Turkey (Türkiye)
Added 1 new site: San Miguel de Tucumán, Argentina
Added 5 new sites: The Woodlands, Texas, Brussels, Belgium, Belo Horizonte,Minas Gerais, Brazil and 2 more
Target enrollment increased from 30 to 40
Eligibility criteria have been updated
Added 10 new sites: Long Beach, California, Owensboro, Kentucky, Bethesda, Maryland and 7 more
Added 17 new sites: Nashville, Tennessee, Ciudad Autonoma de Buenos Aires, Argentina, Rosario, Argentina and 14 more
Added 3 new sites: Isehara, Japan, Miyazaki, Japan, Osaka, Japan
Eligibility criteria have been updated
Added 4 new sites: Maywood, Illinois, Coon Rapids, Minnesota, Minneapolis, Minnesota and 1 more
Added 9 new sites: Boston, Massachusetts, Westbury, New York, Sint-Niklaas, Belgium and 6 more
Added 3 new sites: Saint-Herblain, France, Pozuelo de Alarcón, Spain, Barcelona, Spain
Added 1 new site: Cincinnati, Ohio
Added 1 new site: New Taipei City, Taiwan
Added 1 new site: Winston-Salem, North Carolina
Added 1 new site: Khon Kaen, Thailand
Eligibility criteria have been updated
Added 2 new sites: Canton, Ohio, Madison, Wisconsin
Eligibility criteria have been updated
Target enrollment decreased from 496 to 264
Added 2 new sites: Louisville, Kentucky, Irving, Texas
Added 8 new sites: Beijing, China, Guangzhou, China, Zhengzhou, China and 5 more
Target enrollment increased from 308 to 460
Eligibility criteria have been updated
Added 3 new sites: Madera, California, Carroll, Iowa, Houston, Texas
Added 6 new sites: Aarhus Nord, Denmark, Odense, Denmark, Bunkyo, Japan and 3 more
Target enrollment increased from 10 to 20
Added 2 new sites: Tel Aviv, Israel, Istanbul, Turkey (Türkiye)
Added 1 new site: Layton, Utah
Added 4 new sites: Newport Beach, California, Boston, Massachusetts, Houston, Texas and 1 more
Added 5 new sites: Santiago, Chile, Nagoya, Japan, Kamogawa, Japan and 2 more
Target enrollment decreased from 20 to 10
Added 2 new sites: Herston, Australia, Adelaide, Australia
Added 4 new sites: Iowa City, Iowa, Madrid, Spain, Málaga, Spain and 1 more
Added 2 new sites: Herston, Australia, Adelaide, Australia
Added 6 new sites: San Diego, California, Hialeah, Florida, Morehead City, North Carolina and 3 more
Added 2 new sites: Merano, Italy, Milan, Italy
Added 1 new site: Lille, France
Added 10 new sites: Philadelphia, Pennsylvania, London, Canada, Ludwigshafen, Germany and 7 more
Added 8 new sites: Miami, Florida, Chicago, Illinois, Iowa City, Iowa and 5 more
Added 2 new sites: Philadelphia, Pennsylvania, Nuevo León, Mexico
Added 1 new site: Boston, Massachusetts
Added 5 new sites: Chongqing, China, Shenyang, China, Kolkata, India and 2 more
Added 1 new site: Durham, North Carolina
Added 1 new site: Kansas City, Missouri
Eligibility criteria have been updated
Reduced from 86 to 84 sites
Added 6 new sites: Phoenix, Arizona, Oceanside, California, Delray Beach, Florida and 3 more
Eligibility criteria have been updated
Added 1 new site: Birmingham, Alabama
Target enrollment increased from 662 to 737
Eligibility criteria have been updated
Added 7 new sites: Westbury, New York, Caba, Argentina, San Miguel de Tucumán, Argentina and 4 more
Eligibility criteria have been updated
Added 21 new sites: Huntsville, Alabama, Chula Vista, California, San Dimas, California and 18 more
Reduced from 101 to 97 sites
Added 3 new sites: Hà Nội, Vietnam, Hà Nội, Vietnam, Ho Chi Minh City, Vietnam
Reduced from 89 to 83 sites
Added 3 new sites: Salt Lake City, Utah, Bron, France, Paris, France
Added 14 new sites: Minneapolis, Minnesota, Durham, North Carolina, Cincinnati, Ohio and 11 more
Target enrollment increased from 60 to 160
Eligibility criteria have been updated
Added 2 new sites: San Francisco, California, Tübingen, Germany
Added 1 new site: Port Charlotte, Florida
Added 3 new sites: Miami, Florida, Halle, Germany, Catania, Italy
Eligibility criteria have been updated
Added 8 new sites: Huntsville, Alabama, Tucson, Arizona, La Mesa, California and 5 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 2 new sites: Mount Kisco, New York, Beaverton, Oregon
Added 1 new site: Belo Horizonte, Brazil
Target enrollment increased from 237 to 300
Eligibility criteria have been updated
Added 2 new sites: Hong Kong, Hong Kong, Hong Kong, Hong Kong
Target enrollment increased from 195 to 240
Added 3 new sites: Jacksonville, Florida, Berlin, Germany, Madrid, Spain
Added 1 new site: Seattle, Washington
Added 2 new sites: Durham, North Carolina, Portland, Oregon
Added 2 new sites: Paris, France, Jena, Germany
Reduced from 39 to 35 sites
Added 1 new site: Madera, California
Added 10 new sites: Wilmington, Delaware, Baltimore, Maryland, Cincinnati, Ohio and 7 more
Added 1 new site: Los Angeles, California
Reduced from 101 to 97 sites
Target enrollment decreased from 95 to 19
Added 1 new site: Fort Worth, Texas
Added 1 new site: Tokyo, Japan
Target enrollment decreased from 692 to 37
Added 2 new sites: New York, New York, New York, New York
Target enrollment increased from 184 to 224
Eligibility criteria have been updated
Added 1 new site: Los Angeles, California
Eligibility criteria have been updated
Added 1 new site: Los Angeles, California
Added 1 new site: Los Angeles, California
Target enrollment increased from 121 to 183
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Auckland, New Zealand
Added 2 new sites: San Diego, California, Miami, Florida
Eligibility criteria have been updated
Added 5 new sites: Reno, Nevada, Albuquerque, New Mexico, Philadelphia, Pennsylvania and 2 more
Added 2 new sites: Beijing, China, Hunan, China
Added 2 new sites: Colorado Springs, Colorado, Johnson City, Tennessee
Added 2 new sites: Colorado Springs, Colorado, Johnson City, Tennessee
Added 3 new sites: Rochester, Minnesota, Huntington, West Virginia, Coimbra, Portugal
Reduced from 101 to 97 sites
Added 4 new sites: Plantation, Florida, Tamarac, Florida, Bethesda, Maryland and 1 more
Added 2 new sites: Guangzhou, China, Yantai, China
Moved from N/A to Phase 1
Added 15 new sites: Garran, Australia, Anderlecht, Belgium, Turnhout, Belgium and 12 more
Added 17 new sites: Redwood City, California, Miami, Florida, Cincinnati, Ohio and 14 more
Added 3 new sites: Denver, North Carolina, Cincinnati, Ohio, Sugar Land, Texas
Added 5 new sites: Cullman, Alabama, Kansas City, Kansas, Middletown, New Jersey and 2 more
Added 1 new site: München, Germany
Added 8 new sites: Indianapolis, Indiana, Leuven, Belgium, Copenhagen, Denmark and 5 more
Reduced from 101 to 97 sites
Added 2 new sites: Guangzhou, China, Yantai, China
Added 1 new site: Hackensack, New Jersey
Reduced from 5 to 2 sites
Target enrollment increased from 24 to 30
Eligibility criteria have been updated
Added 15 new sites: Garran, Australia, Anderlecht, Belgium, Turnhout, Belgium and 12 more
Added 2 new sites: New York, New York, Westmead, Australia
Added 6 new sites: Jacksonville, Florida, Miami, Florida, Box Hill, Australia and 3 more
Target enrollment increased from 5 to 15
Eligibility criteria have been updated
Added 1 new site: Columbus, Ohio
Added 3 new sites: Palo Alto, California, New York, New York, Westmead, Australia
Added 1 new site: Umeå, Sweden
Target enrollment increased from 42 to 54
Added 1 new site: Livonia, Michigan
Eligibility criteria have been updated
Added 1 new site: Poznan, Poland
Added 1 new site: Kansas City, Kansas
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: London, United Kingdom
Added 4 new sites: Clayton, Australia, Concord, Australia, Bari, Italy and 1 more
Eligibility criteria have been updated
Added 6 new sites: Orlando, Florida, New York, New York, Philadelphia, Pennsylvania and 3 more
Added 3 new sites: Kitakyushu, Japan, Kobe, Japan, Nagaoka, Japan
Eligibility criteria have been updated
Added 6 new sites: San Miguel de Tucumán, Argentina, Buenos Aires, Argentina, Santa Fe, Argentina and 3 more
Eligibility criteria have been updated
Added 7 new sites: Kansas City, Kansas, Baltimore, Maryland, Salt Lake City, Utah and 4 more
Added 2 new sites: Salt Lake City, Utah, Warsaw, Poland
Added 2 new sites: Mount Kisco, New York, Beaverton, Oregon
Added 2 new sites: Clayton, Australia, Cambridge, United Kingdom
Eligibility criteria have been updated
Added 4 new sites: Chicago, Illinois, Des Moines, Iowa, Las Vegas, Nevada and 1 more
Reduced from 24 to 21 sites
Eligibility criteria have been updated
Target enrollment increased from 27 to 45
Added 2 new sites: Houston, Texas, Houston, Texas
Added 9 new sites: Chicago, Illinois, Fort Wayne, Indiana, Pittsburgh, Pennsylvania and 6 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 7 new sites: Chicago, Illinois, Glenview, Illinois, Highland Park, Illinois and 4 more
Reduced from 71 to 54 sites
Added 2 new sites: Catania, Italy, Padua, Italy
Added 1 new site: Chicago, Illinois
Added 1 new site: Tianjin, China
Added 1 new site: Miami, Florida
Eligibility criteria have been updated
Added 3 new sites: Montreal, Canada, Québec, Canada, Frankfurt am Main, Germany
Added 4 new sites: Burbank, California, Walnut Creek, California, Lenexa, Kansas and 1 more
Added 2 new sites: Irvine, California, Durham, North Carolina
Added 1 new site: Austin, Texas
Reduced from 174 to 152 sites
Target enrollment decreased from 820 to 524
Added 2 new sites: Guangzhou, China, Yantai, China
Added 2 new sites: Durham, North Carolina, Portland, Oregon
Added 1 new site: Miami, Florida
Added 2 new sites: Detroit, Michigan, Pittsburgh, Pennsylvania
Added 1 new site: Birmingham, Alabama
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Lebanon, New Hampshire
Eligibility criteria have been updated
Target enrollment increased from 56 to 258
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment increased from 100 to 210
Added 2 new sites: Birmingham, Alabama, Indianapolis, Indiana
Added 13 new sites: Chicago, Illinois, Dijon, France, Marseille, France and 10 more
Added 2 new sites: New Haven, Connecticut, New Delhi, India
Eligibility criteria have been updated
Reduced from 61 to 58 sites
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 4 new sites: Philadelphia, Pennsylvania, Curitiba, Brazil, Porto Alegre, Brazil and 1 more
Target enrollment increased from 150 to 200
Eligibility criteria have been updated
Added 2 new sites: New York, New York, Westmead, Australia
Added 1 new site: Lebanon, New Hampshire
Eligibility criteria have been updated
Added 23 new sites: Buenos Aires, Argentina, Buenos Aires, Argentina, San Luis, Argentina and 20 more
Added 3 new sites: Palo Alto, California, New York, New York, Westmead, Australia
Eligibility criteria have been updated
Added 2 new sites: Berlin, Germany, Roma, Italy
Added 4 new sites: Washington D.C., District of Columbia, Pittsburgh, Pennsylvania, Houston, Texas and 1 more
Added 3 new sites: Owensboro, Kentucky, Hefei, China, Wuhan, China
Added 32 new sites: Beverly Hills, California, Atlanta, Georgia, Louisville, Kentucky and 29 more
Reduced from 19 to 4 sites
Added 2 new sites: Nedlands, Australia, Barcelona, Spain
Added 13 new sites: El Centro, California, Fremont, California, Stanford, California and 10 more
Eligibility criteria have been updated
Added 21 new sites: Beijing, China, Yuncheng, China, Tianjin, China and 18 more
Added 1 new site: Salt Lake City, Utah
Eligibility criteria have been updated
Reduced from 23 to 18 sites
Added 5 new sites: Marseille, France, Marseille, France, Nantes, France and 2 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 2 new sites: Tampa, Florida, Milan, Italy
Added 13 new sites: Feldkirch, Austria, Brussels, Belgium, Bruges, Belgium and 10 more
Added 40 new sites: Beijing, China, Beijing, China, Beijing, China and 37 more
Added 3 new sites: CABA, Argentina, Aarhus, Denmark, A Coruña, Spain
Added 2 new sites: Fredericton, Canada, Saskatoon, Canada
Added 2 new sites: Milan, Italy, Umeå, Sweden
Added 1 new site: Boston, Massachusetts
Added 1 new site: Würzburg, Germany
Added 1 new site: Baltimore, Maryland
Added 1 new site: Stockholm, Sweden