Rare Disease Trial Updates: September 2026
In September 2026, Trial Friend tracked 895 rare disease clinical trial updates across 115 conditions, including 10 FDA-related actions and 162 trial status changes, alongside enrollment updates and new trial site openings sourced from ClinicalTrials.gov and FDA announcements.
This is a permanent monthly archive. For the latest updates, see the live current events feed.
Major Updates: FDA Actions, Status Changes & Results
Now recruiting (was Active Not Recruiting)
No longer enrolling new participants
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The U.S. Attorney’s Office for the Middle District of Florida and the Criminal Division of the U.S. Department of Justice today announced federal charges against Swapnadip Roy, 33, and Vicky Ramancha, 37, both Indian nationals.
No longer enrolling new participants
No longer enrolling new participants
Lexeo Therapeutics (LXEO) filed an 8-K with the SEC on 2026-09-29 covering: acquisition or disposition completed. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Cadrenal Therapeutics (CVKD) filed an 8-K with the SEC on 2026-09-29 covering: leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Dyne Therapeutics (DYN) filed an 8-K with the SEC on 2026-09-29 covering: company event. The filing mentions Myotonic Dystrophy. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
The U.S. Food and Drug Administration today approved Emcitate (tiratricol) tablets for oral suspension to treat peripheral thyrotoxicosis (excess thyroid hormone levels in the blood that causes symptoms, such as rapid heart rate, increased blood pressure and adverse effects on metabolism) in patient
Mirum Pharmaceuticals (MIRM) filed an 8-K with the SEC on 2026-09-28 covering: company event. The filing mentions Fibrodysplasia Ossificans Progressiva. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
Stoke Therapeutics (STOK) filed an 8-K with the SEC on 2026-09-25 covering: leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
No longer enrolling new participants
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No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
Status changed from Recruiting to Enrolling By Invitation
Corcept Therapeutics (CORT) filed an 8-K with the SEC on 2026-09-23 covering: leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Ionis Pharmaceuticals (IONS) filed an 8-K with the SEC on 2026-09-23 covering: company event. The filing mentions IgA Nephropathy. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Jazz Pharmaceuticals (JAZZ) filed an 8-K with the SEC on 2026-09-23 covering: material agreement. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Sarepta Therapeutics (SRPT) filed an 8-K with the SEC on 2026-09-23 covering: material agreement. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Regenxbio (RGNX) filed an 8-K with the SEC on 2026-09-23 covering: material agreement. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
Now recruiting (was Enrolling By Invitation)
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Lexeo Therapeutics (LXEO) filed an 8-K with the SEC on 2026-09-22 covering: material agreement, company event. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
No longer enrolling new participants
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The FDA today issued a direct final rule that updates its regulations to clarify that non-animal methods can be used where appropriate for testing the safety of drugs and biological products intended for human use before they’re tried in humans.
PTC Therapeutics (PTCT) filed an 8-K with the SEC on 2026-09-21 covering: company event. The filing mentions Fabry Disease. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Retrophin (now Travere Therapeutics) (TVTX) filed an 8-K with the SEC on 2026-09-21 covering: leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
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Now recruiting (was Active Not Recruiting)
The U.S. Food and Drug Administration today approved Fayuvi (rebisufligene etisparvovec-hopf), the first treatment for pediatric patients with mucopolysaccharidosis type IIIA (MPS IIIA), also known as Sanfilippo syndrome type A.
No longer enrolling new participants
Ultragenyx Pharmaceutical (RARE) filed an 8-K with the SEC on 2026-09-17 covering: company event. The filing mentions Mucopolysaccharidosis Type III. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
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Now recruiting (was Active Not Recruiting)
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
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No longer enrolling new participants
The U.S. Food and Drug Administration today announced the final design of the Expedited Investigational New Drug (IND) Pilot.
BioMarin Pharmaceutical (BMRN) filed an 8-K with the SEC on 2026-09-15 covering: company event. The filing mentions Noonan Syndrome. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
No longer enrolling new participants
Cabaletta Bio (CABA) filed an 8-K with the SEC on 2026-09-14 covering: company event. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
BioMarin Pharmaceutical (BMRN) filed an 8-K with the SEC on 2026-09-14 covering: leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
Now recruiting (was Active Not Recruiting)
No longer enrolling new participants
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Now recruiting (was Active Not Recruiting)
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Status changed from Active Not Recruiting to Enrolling By Invitation
No longer enrolling new participants
No longer enrolling new participants
Biohaven (BHVN) filed an 8-K with the SEC on 2026-09-10 covering: company event. The filing mentions Focal Epilepsy. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
No longer enrolling new participants
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Now recruiting (was Enrolling By Invitation)
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No longer enrolling new participants
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No longer enrolling new participants
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No longer enrolling new participants
Mirum Pharmaceuticals (MIRM) filed an 8-K with the SEC on 2026-09-08 covering: leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Keros Therapeutics (KROS) filed an 8-K with the SEC on 2026-09-08 covering: company event. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Intellia Therapeutics (NTLA) filed an 8-K with the SEC on 2026-09-08 covering: company event. The filing mentions Hereditary Angioedema. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
Status changed from Active Not Recruiting to Enrolling By Invitation
No longer enrolling new participants
No longer enrolling new participants
Now recruiting (was Active Not Recruiting)
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
Status changed from Recruiting to Enrolling By Invitation
No longer enrolling new participants
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No longer enrolling new participants
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The U.S. Food and Drug Administration today announced it is taking action, consistent with the Trump administration’s commitment to protecting vulnerable patients and maintaining access to critical medical products, to help address a potential supply gap of neonatal starter parenteral nutrition (PN)
The U.S. Food and Drug Administration today expanded treatment options for adult patients with advanced breast cancer, reflecting the FDA’s commitment to advancing medical innovation and getting new treatments to patients who need them.
No longer enrolling new participants
No longer enrolling new participants
Intellia Therapeutics (NTLA) filed an 8-K with the SEC on 2026-09-04 covering: material agreement. The filing mentions Hereditary Angioedema. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Ionis Pharmaceuticals (IONS) filed an 8-K with the SEC on 2026-09-04 covering: company event. The filing mentions Alexander Disease. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
The U.S. Food and Drug Administration has approved Zanvastro (zilganersen) injection for the treatment of Alexander disease in pediatric and adult patients.
No longer enrolling new participants
No longer enrolling new participants
Status changed from Recruiting to Enrolling By Invitation
No longer enrolling new participants
No longer enrolling new participants
No longer enrolling new participants
The U.S. Food and Drug Administration today issued an Emergency Use Authorization (EUA) for Capstar (nitenpyram) tablets and revised the EUA for Nitenpyram Tablets, the generic version of Capstar
The U.S. Food and Drug Administration today announced a request for information (RFI) to gather public input on opportunities to advance the development of botanical drug products.
No longer enrolling new participants
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No longer enrolling new participants
Ultragenyx Pharmaceutical (RARE) filed an 8-K with the SEC on 2026-09-02 covering: company event. The filing mentions Angelman Syndrome. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Cogent Biosciences (COGT) filed an 8-K with the SEC on 2026-09-02 covering: material agreement. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
No longer enrolling new participants
BioMarin Pharmaceutical (BMRN) filed an 8-K with the SEC on 2026-09-01 covering: company event. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Vertex Pharmaceuticals (VRTX) filed an 8-K with the SEC on 2026-09-01 covering: leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Crinetics Pharmaceuticals (CRNX) filed an 8-K with the SEC on 2026-09-01 covering: agreement terminated, acquisition or disposition completed, stock listing notice, leadership change. Companies must file 8-Ks for material events within 4 business days, and clinical, regulatory, and business news sometimes appears here before any press release.
Trial Site & Enrollment Activity
Added 1 new site: Chicago, Illinois
Added 3 new sites: Campinas, Brazil, Halifax, Canada, Setagaya-ku, Japan
Added 3 new sites: Montpellier, France, Nice, France, Kodaira, Japan
Eligibility criteria have been updated
Added 26 new sites: New Brunswick, New Jersey, New York, New York, Cincinnati, Ohio and 23 more
Reduced from 13 to 11 sites
Added 9 new sites: Salt Lake City, Utah, Strasbourg, France, Milan, Italy and 6 more
Eligibility criteria have been updated
Added 1 new site: Bad Nauheim, Germany
Target enrollment increased from 350 to 400
Eligibility criteria have been updated
Added 66 new sites: Birmingham, Alabama, Rancho Mirage, California, Naples, Florida and 63 more
Reduced from 23 to 15 sites
Eligibility criteria have been updated
Added 1 new site: Kropyvnytskyi, Ukraine
Added 5 new sites: San Diego, California, New York, New York, The Bronx, New York and 2 more
Added 2 new sites: Hangzhou, China, Shijiazhuang, China
Added 2 new sites: Stamford, Connecticut, Miami, Florida
Added 13 new sites: Chongqing, China, Fuzhou, China, Guangzhou, China and 10 more
Added 3 new sites: Stanford, California, Saint Cloud, Minnesota, The Bronx, New York
Added 2 new sites: Milan, Italy, Leiden, Netherlands
Target enrollment decreased from 136 to 107
Added 1 new site: Temple, Texas
Added 2 new sites: Valhalla, New York, Portland, Oregon
Added 1 new site: Bangalore, India
Target enrollment increased from 128 to 160
Target enrollment increased from 60 to 200
Eligibility criteria have been updated
Added 3 new sites: Rio de Janeiro, Brazil, Pôrto Alegre, Brazil, Ribeirão Preto, Brazil
Eligibility criteria have been updated
Added 27 new sites: Clermont, Florida, Fort Wayne, Indiana, Bethesda, Maryland and 24 more
Added 14 new sites: San Diego, California, Golden, Colorado, Grand Rapids, Michigan and 11 more
Eligibility criteria have been updated
Target enrollment decreased from 170 to 136
Added 4 new sites: Hong Kong, Hong Kong, Hong Kong, Hong Kong, Auckland, New Zealand and 1 more
Eligibility criteria have been updated
Target enrollment decreased from 12 to 6
Eligibility criteria have been updated
Added 12 new sites: Hot Springs, Arkansas, San Diego, California, Indianapolis, Indiana and 9 more
Eligibility criteria have been updated
Added 56 new sites: Pheonix, Arizona, West Hollywood, California, Tampa, Florida and 53 more
Added 13 new sites: Birmingham, Alabama, Phoenix, Arizona, Atlanta, Georgia and 10 more
Eligibility criteria have been updated
Added 31 new sites: Mobile, Alabama, Inglewood, California, Bradenton, Florida and 28 more
Eligibility criteria have been updated
Added 4 new sites: Guangzhou, China, Guangzhou, China, Hangzhou, China and 1 more
Added 10 new sites: Macquarie University, Australia, Melbourne, Australia, Randwick, Australia and 7 more
Added 1 new site: Las Vegas, Nevada
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment increased from 150 to 188
Added 3 new sites: Kingston, Canada, Toronto, Canada, Québec, Canada
Added 17 new sites: Los Angeles, California, Medford, Oregon, DuBois, Pennsylvania and 14 more
Added 6 new sites: Miami, Florida, Mineola, New York, Oklahoma City, Oklahoma and 3 more
Target enrollment decreased from 70 to 32
Added 2 new sites: Milan, Italy, Leiden, Netherlands
Added 1 new site: Nantes, France
Added 3 new sites: Los Angeles, California, Columbus, Ohio, Memphis, Tennessee
Target enrollment increased from 10 to 30
Eligibility criteria have been updated
Added 2 new sites: Allentown, Pennsylvania, Buenos Aires, Argentina
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Calgary, Canada
Added 1 new site: Calgary, Canada
Added 1 new site: Jacksonville, Florida
Eligibility criteria have been updated
Added 4 new sites: Dallas, Texas, Québec, Canada, Milan, Italy and 1 more
Added 3 new sites: Liège, Belgium, Liège, Belgium, London, United Kingdom
Target enrollment increased from 40 to 140
Eligibility criteria have been updated
Added 1 new site: Oakville, Canada
Target enrollment increased from 24 to 39
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 12 new sites: Pazardzhik, Bulgaria, Varna, Bulgaria, Varna, Bulgaria and 9 more
Added 3 new sites: Jacksonville, Florida, Miami, Florida, Albany, New York
Added 1 new site: Paris, France
Added 1 new site: Paris, France
Added 1 new site: Lille, France
Added 1 new site: Santiago, Chile
Added 7 new sites: Athens, Greece, Budapest, Hungary, Mérida, Mexico and 4 more
Eligibility criteria have been updated
Added 1 new site: Pittsburgh, Pennsylvania
Added 1 new site: Portland, Oregon
Added 2 new sites: Banja Luka, Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina
Target enrollment increased from 200 to 1000
Added 2 new sites: Brisbane, Australia, London, United Kingdom
Added 1 new site: Atlanta, Georgia
Added 20 new sites: Fort Myers, Florida, Miami, Florida, St. Petersburg, Florida and 17 more
Added 3 new sites: Birmingham, Alabama, Brookline, Massachusetts, New York, New York
Added 2 new sites: Washington D.C., District of Columbia, Atlanta, Georgia
Added 1 new site: Changsha, China
Reduced from 41 to 38 sites
Added 1 new site: Paris, France
Added 1 new site: Paris, France
Added 1 new site: Paris, France
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 2 new sites: Rochester, New York, Göttingen, Germany
Added 6 new sites: Fort Myers, Florida, Dallas, Texas, Ostrava, Czechia and 3 more
Added 2 new sites: Melbourne, Australia, Athens, Greece
Added 2 new sites: Foxborough, Massachusetts, Austin, Texas
Added 3 new sites: Alicante, Spain, Barcelona, Spain, Madrid, Spain
Added 1 new site: Pasadena, California
Added 1 new site: Goodyear, Arizona
Added 1 new site: Duarte, California
Added 11 new sites: Chula Vista, California, Colorado Springs, Colorado, Winter Park, Florida and 8 more
Added 1 new site: Philadelphia, Pennsylvania
Added 1 new site: Nantes, France
Eligibility criteria have been updated
Added 1 new site: Tokyo, Japan
Added 15 new sites: Miami, Florida, St. Petersburg, Florida, Sankt Pölten, Austria and 12 more
Added 13 new sites: New Haven, Connecticut, Monroe, Louisiana, Shreveport, Louisiana and 10 more
Added 1 new site: Harvey, Illinois
Added 1 new site: Greenville, South Carolina
Added 6 new sites: Las Vegas, Nevada, Chapel Hill, North Carolina, Cincinnati, Ohio and 3 more
Added 1 new site: Austin, Texas
Added 6 new sites: Las Vegas, Nevada, Chapel Hill, North Carolina, Cincinnati, Ohio and 3 more
Added 1 new site: Melbourne, Australia
Eligibility criteria have been updated
Added 2 new sites: Kansas City, Kansas, Katowice, Poland
Added 2 new sites: Lincoln, Nebraska, London, United Kingdom
Added 1 new site: Warsaw, Poland
Added 6 new sites: La Jolla, California, Rochester, Minnesota, New York, New York and 3 more
Added 2 new sites: Tampa, Florida, Poznan, Poland
Reduced from 160 to 158 sites
Eligibility criteria have been updated
Added 45 new sites: Birmingham, Alabama, Bullhead City, Arizona, Casa Grande, Arizona and 42 more
Added 1 new site: Portland, Oregon
Eligibility criteria have been updated
Added 3 new sites: Phoenix, Arizona, Jacksonville, Florida, Rochester, Minnesota
Added 1 new site: Gilbert, Arizona
Added 1 new site: Chuo Ku, Japan
Added 1 new site: Indianapolis, Indiana
Added 1 new site: Gilbert, Arizona
Added 1 new site: Chuo Ku, Japan
Added 1 new site: Santiago, Chile
Added 3 new sites: Nice, France, Kaohsiung City, Taiwan, Taipei, Taiwan
Added 2 new sites: Odense C, Denmark, Bergamo, Italy
Added 1 new site: Utrecht, Netherlands
Target enrollment increased from 65 to 130
Added 1 new site: Barcelona, Spain
Added 1 new site: CABA, Argentina
Eligibility criteria have been updated
Added 4 new sites: Bruges, Belgium, Ulm, Germany, Dublin, Ireland and 1 more
Added 1 new site: Williamsville, New York
Reduced from 32 to 29 sites
Added 24 new sites: Bakersfield, California, Coral Gables, Florida, Coral Springs, Florida and 21 more
Eligibility criteria have been updated
Added 1 new site: Osaka, Japan
Reduced from 45 to 43 sites
Added 19 new sites: Sacramento, California, Detroit, Michigan, New York, New York and 16 more
Added 5 new sites: Newcastle, Australia, Penrith, Australia, Sydney, Australia and 2 more
Added 3 new sites: Kanazawa, Japan, Barcelona, Spain, Taipei, Taiwan
Added 1 new site: Hannibal, Missouri
Added 4 new sites: Camperdown, Australia, Amsterdam, Netherlands, Heerlen, Netherlands and 1 more
Added 3 new sites: Lima, Peru, San Miguel, Peru, Bydgoszcz, Poland
Added 37 new sites: San Francisco, California, Miami, Florida, Chicago, Illinois and 34 more
Added 2 new sites: Taufkirchen, Germany, Madrid, Spain
Added 6 new sites: Duarte, California, Lexington, Kentucky, Hackensack, New Jersey and 3 more
Added 17 new sites: Crown Point, Indiana, Dyer, Indiana, Hobart, Indiana and 14 more
Target enrollment increased from 176 to 250
Eligibility criteria have been updated
Added 3 new sites: Orlando, Florida, Atlanta, Georgia, Glasgow, United Kingdom
Added 2 new sites: São Paulo, Brazil, São Paulo, Brazil
Eligibility criteria have been updated
Target enrollment decreased from 25 to 2
Added 4 new sites: Miami, Florida, Charlottesville, Virginia, East Melbourne, Australia and 1 more
Target enrollment increased from 255 to 329
Eligibility criteria have been updated
Added 1 new site: Calgary, Canada
Eligibility criteria have been updated
Target enrollment increased from 32 to 48
Eligibility criteria have been updated
Added 2 new sites: Flowood, Mississippi, Taipei, Taiwan
Added 5 new sites: Beijing, China, Lille, France, Zurich, Switzerland and 2 more
Added 26 new sites: Birmingham, Alabama, Orange, California, San Francisco, California and 23 more
Added 12 new sites: Miami, Florida, St. Petersburg, Florida, Florianópolis, Brazil and 9 more
Added 6 new sites: Hollywood, Florida, Baton Rouge, Louisiana, Kansas City, Missouri and 3 more
Added 4 new sites: Jacksonville, Florida, Miami, Florida, Kansas City, Missouri and 1 more
Added 17 new sites: Pazardzhik, Bulgaria, Sliven, Bulgaria, Varna, Bulgaria and 14 more
Expanded from 45 to 46 sites
Added 60 new sites: Avondale, Arizona, Phoenix, Arizona, Tucson, Arizona and 57 more
Added 1 new site: Rouen, France
Added 14 new sites: Beverly Hills, California, Encino, California, Sacramento, California and 11 more
Reduced from 65 to 58 sites
Added 1 new site: Barcelona, Spain
Reduced from 309 to 307 sites
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 4 new sites: Phoenix, Arizona, San Diego, California, Stanford, California and 1 more
Target enrollment increased from 15 to 50
Eligibility criteria have been updated
Target enrollment increased from 76 to 256
Eligibility criteria have been updated
Added 4 new sites: Jinan, China, Padova, Italy, Bunkyo Ku, Japan and 1 more
Eligibility criteria have been updated
Expanded from 45 to 46 sites
Added 14 new sites: Aschaffenburg, Germany, Augsburg, Germany, Erlangen, Germany and 11 more
Added 1 new site: Nantes, France
Target enrollment decreased from 44 to 19
Added 1 new site: Minneapolis, Minnesota
Reduced from 135 to 133 sites
Added 6 new sites: Nicholasville, Kentucky, São Paulo, Brazil, Calgary, Canada and 3 more
Added 7 new sites: Miami Lakes, Florida, New York, New York, Belo Horizonte, Brazil and 4 more
Target enrollment decreased from 140 to 109
Eligibility criteria have been updated
Added 6 new sites: La Jolla, California, Rochester, Minnesota, New York, New York and 3 more
Added 2 new sites: Songpa-dong, South Korea, Sanmin, Taiwan
Added 1 new site: Osaka, Japan
Reduced from 139 to 127 sites
Target enrollment increased from 9000 to 9082
Added 1 new site: Novi, Michigan
Added 2 new sites: Jacksonville, Florida, Rochester, Minnesota
Added 2 new sites: Loveland, Colorado, Lexington, Kentucky
Target enrollment increased from 100 to 172
Eligibility criteria have been updated
Reduced from 179 to 151 sites
Added 5 new sites: Miami, Florida, Detroit, Michigan, New Brunswick, New Jersey and 2 more
Added 5 new sites: La Jolla, California, Los Angeles, California, Gainesville, Florida and 2 more
Eligibility criteria have been updated
Added 5 new sites: Boston, Massachusetts, New York, New York, South Brisbane, Australia and 2 more
Added 1 new site: Genova, Italy
Added 18 new sites: Melbourne, Australia, Ghent, Belgium, Leuven, Belgium and 15 more
Eligibility criteria have been updated
Added 3 new sites: Los Angeles, California, Columbus, Ohio, Memphis, Tennessee
Target enrollment increased from 10 to 30
Eligibility criteria have been updated
Added 53 new sites: Los Angeles, California, Palo Alto, California, Aurora, Colorado and 50 more
Added 63 new sites: Los Angeles, California, Los Angeles, California, Palo Alto, California and 60 more
Eligibility criteria have been updated
Added 3 new sites: Paris, France, Rennes, France, Toulouse, France
Reduced from 146 to 138 sites
Added 1 new site: Brandon, Florida
Eligibility criteria have been updated
Target enrollment increased from 2000 to 3500
Eligibility criteria have been updated
Added 1 new site: Cypress, Texas
Added 1 new site: Aurora, Colorado
Added 6 new sites: Cincinnati, Ohio, Córdoba, Argentina, Liverpool, Australia and 3 more
Added 13 new sites: Scottsdale, Arizona, Brasília, Brazil, São Paulo, Brazil and 10 more
Added 2 new sites: Stamford, Connecticut, Miami, Florida
Added 4 new sites: Knoxville, Tennessee, Guangzhou, China, Ramat Gan, Israel and 1 more
Added 14 new sites: Oxnard, California, Tainan, China, Taipei, China and 11 more
Added 5 new sites: New York, New York, Belo Horizonte, Brazil, Changchun, China and 2 more
Added 24 new sites: Duarte, California, Orange, California, Aurora, Colorado and 21 more
Added 1 new site: Athens, Greece
Added 7 new sites: Garden Grove, California, Changchun, China, Kashgar, China and 4 more
Added 1 new site: Falls Church, Virginia
Target enrollment increased from 45 to 54
Target enrollment decreased from 82 to 48
Added 3 new sites: San Diego, California, San Antonio, Texas, Lille, France
Reduced from 79 to 74 sites
Target enrollment decreased from 666 to 488
Target enrollment increased from 705 to 845
Added 47 new sites: Phoenix, Arizona, Aurora, Colorado, Tampa, Florida and 44 more
Eligibility criteria have been updated
Added 1 new site: Xi'an, China
Target enrollment decreased from 60 to 18
Added 4 new sites: Beijing, China, Chengdu, China, Hangzhou, China and 1 more
Eligibility criteria have been updated
Added 11 new sites: Ubá, Brazil, Winnipeg, Canada, North York, Canada and 8 more
Eligibility criteria have been updated
Added 6 new sites: Beijing, China, Kanazawa, Japan, Chiba, Japan and 3 more
Added 2 new sites: Rochester, Minnesota, Żory, Poland
Target enrollment decreased from 159 to 76
Added 1 new site: Cincinnati, Ohio
Added 18 new sites: Melbourne, Australia, Ghent, Belgium, Leuven, Belgium and 15 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 5 new sites: La Jolla, California, Los Angeles, California, Gainesville, Florida and 2 more
Eligibility criteria have been updated
Added 1 new site: Genova, Italy
Added 5 new sites: Boston, Massachusetts, New York, New York, South Brisbane, Australia and 2 more
Added 6 new sites: Ulm, Germany, Greifswald, Germany, Bonn, Germany and 3 more
Added 12 new sites: Aurora, Colorado, Austin, Texas, Seattle, Washington and 9 more
Added 7 new sites: Rosario, Argentina, Rio de Janeiro, Brazil, Dublin, Ireland and 4 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 4 new sites: Toronto, Canada, Utrecht, Netherlands, Krakow, Poland and 1 more
Added 2 new sites: Krakow, Poland, Huddinge, Sweden
Reduced from 60 to 58 sites
Eligibility criteria have been updated
Added 1 new site: Fort Worth, Texas
Added 1 new site: Chicago, Illinois
Added 12 new sites: Aurora, Colorado, Austin, Texas, Seattle, Washington and 9 more
Added 6 new sites: Ulm, Germany, Greifswald, Germany, Bonn, Germany and 3 more
Target enrollment increased from 705 to 845
Added 6 new sites: Boise, Idaho, Caldwell, Idaho, Meridian, Idaho and 3 more
Added 2 new sites: Orlando, Florida, Oxford, United Kingdom
Added 8 new sites: San Diego, California, San Francisco, California, Pittsburgh, Pennsylvania and 5 more
Added 1 new site: Lexington, Kentucky
Added 18 new sites: Palo Alto, California, New Haven, Connecticut, Ann Arbor, Michigan and 15 more
Reduced from 36 to 31 sites
Expanded from 106 to 107 sites
Reduced from 48 to 45 sites
Target enrollment increased from 221 to 290
Added 2 new sites: Cincinnati, Ohio, Dallas, Texas
Added 4 new sites: Boston, Massachusetts, Philadelphia, Pennsylvania, Pittsburgh, Pennsylvania and 1 more
Reduced from 35 to 30 sites
Target enrollment decreased from 259 to 97
Target enrollment increased from 2323 to 2586
Target enrollment increased from 408 to 510
Eligibility criteria have been updated
Target enrollment increased from 25 to 35
Added 1 new site: Charlotte, North Carolina
Expanded from 106 to 107 sites
Added 1 new site: Bordeaux, France
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Houston, Texas
Added 1 new site: Greenville, North Carolina
Added 5 new sites: Miami, Florida, Paris, France, Naples, Italy and 2 more
Target enrollment increased from 2000 to 3500
Added 1 new site: Jinan, China
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment decreased from 32 to 18
Eligibility criteria have been updated
Added 6 new sites: Kansas City, Kansas, Omaha, Nebraska, Petah Tikva, Israel and 3 more
Added 3 new sites: Omaha, Nebraska, Cincinnati, Ohio, Strasbourg, France
Added 4 new sites: Los Angeles, California, Aurora, Colorado, Cincinnati, Ohio and 1 more
Added 2 new sites: Creixomil, Portugal, Porto, Portugal
Target enrollment increased from 318 to 402
Eligibility criteria have been updated
Added 6 new sites: Seattle, Washington, Aurangabad, India, Padova, Italy and 3 more
Target enrollment increased from 76 to 256
Eligibility criteria have been updated
Added 2 new sites: East Brunswick, New Jersey, Maumee, Ohio
Added 1 new site: Taichung, Taiwan
Added 2 new sites: Columbus, Ohio, St. George, Utah
Eligibility criteria have been updated
Added 1 new site: Skorzewo, Poland
Target enrollment increased from 76 to 256
Eligibility criteria have been updated
Added 1 new site: Taichung, Taiwan
Added 7 new sites: Nice, France, Pessac, France, Chorzów, Poland and 4 more
Added 2 new sites: Baltimore, Maryland, Tokyo, Japan
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 5 new sites: Columbus, Ohio, Plovdiv, Bulgaria, Sofia, Bulgaria and 2 more
Added 17 new sites: Cullman, Alabama, Gainesville, Florida, Orlando, Florida and 14 more
Added 1 new site: Genova, Italy
Added 2 new sites: East Brunswick, New Jersey, Maumee, Ohio
Added 7 new sites: Seattle, Washington, Aurangabad, India, Padova, Italy and 4 more
Added 1 new site: Auckland, New Zealand
Added 2 new sites: East Brunswick, New Jersey, Maumee, Ohio
Target enrollment increased from 78 to 156
Eligibility criteria have been updated
Added 1 new site: Columbus, Ohio
Added 5 new sites: Belgrade, Serbia, Niš, Serbia, Novi Sad, Serbia and 2 more
Added 1 new site: Randwick, Australia
Added 2 new sites: Marseille, France, Fuchū, Japan
Eligibility criteria have been updated
Added 1 new site: Detroit, Michigan
Added 2 new sites: Tampa, Florida, Hradec Králové, Czechia
Added 2 new sites: Krakow, Poland, Huddinge, Sweden
Reduced from 32 to 26 sites
Eligibility criteria have been updated
Eligibility criteria have been updated
Moved from Phase 1 to Phase 1, Phase 2
Target enrollment increased from 100 to 160
Eligibility criteria have been updated
Added 4 new sites: Glendale, California, Long Beach, California, New Orleans, Louisiana and 1 more
Eligibility criteria have been updated
Added 1 new site: Boston, Massachusetts
Target enrollment decreased from 259 to 105
Added 2 new sites: Madrid, Spain, Malmö, Sweden
Added 2 new sites: Olomouc, Czechia, Birmingham, United Kingdom
Added 1 new site: La Boca, Argentina
Expanded from 54 to 55 sites
Added 1 new site: New York, New York
Reduced from 43 to 36 sites
Added 6 new sites: Boise, Idaho, Caldwell, Idaho, Meridian, Idaho and 3 more
Added 2 new sites: Novara, Italy, Reggio Emilia, Italy
Added 4 new sites: Essen, Germany, Bydgoszcz, Poland, Kaohsiung City, Taiwan and 1 more
Target enrollment increased from 470 to 580
Eligibility criteria have been updated
Added 1 new site: Brisbane, Australia
Added 53 new sites: Los Angeles, California, Palo Alto, California, Aurora, Colorado and 50 more
Added 3 new sites: Dallas, Texas, Genoa, Italy, Belgrade, Serbia
Target enrollment decreased from 210 to 153
Added 4 new sites: Kissimmee, Florida, New Orleans, Louisiana, Winston-Salem, North Carolina and 1 more
Eligibility criteria have been updated
Target enrollment decreased from 32 to 11
Eligibility criteria have been updated
Reduced from 32 to 28 sites
Target enrollment increased from 100 to 130
Eligibility criteria have been updated
Moved from Phase 2 to Phase 1, Phase 2
Reduced from 39 to 36 sites
Added 7 new sites: Washington D.C., District of Columbia, Burr Ridge, Illinois, Homer Glen, Illinois and 4 more
Added 1 new site: Lexington, Kentucky
Added 1 new site: Tokyo, Japan
Added 1 new site: Torino, Italy
Expanded from 64 to 65 sites
Reduced from 266 to 264 sites
Added 3 new sites: Irvine, California, Los Angeles, California, Orange, California
Target enrollment increased from 33 to 83
Added 5 new sites: Athens, Georgia, Reno, Nevada, Shirley, New York and 2 more
Added 1 new site: Charlotte, North Carolina
Added 13 new sites: Adelaide, Australia, Melbourne, Australia, Melbourne, Australia and 10 more
Eligibility criteria have been updated
Added 4 new sites: Suzhou, China, Shenyang, China, Chuo-ku, Japan and 1 more
Added 1 new site: Hong Kong, Hong Kong
Target enrollment decreased from 68 to 45
Reduced from 24 to 20 sites
Added 5 new sites: Boise, Idaho, Caldwell, Idaho, Meridian, Idaho and 2 more
Eligibility criteria have been updated
Added 3 new sites: Seattle, Washington, Aurangabad, India, Katowice, Poland
Added 2 new sites: East Brunswick, New Jersey, Maumee, Ohio
Moved from Phase 2 to Phase 2, Phase 3
Reduced from 177 to 175 sites
Added 2 new sites: Kobe, Japan, Fukuoka, Japan
Added 3 new sites: Shanghai, China, Singapore, Singapore, Icheon, South Korea
Added 2 new sites: Kobe, Japan, Fukuoka, Japan
Target enrollment decreased from 259 to 105
Target enrollment decreased from 259 to 105
Added 2 new sites: Izumi, Japan, Suita, Japan
Added 2 new sites: Boston, Massachusetts, Durham, North Carolina
Added 1 new site: Bad Nauheim, Germany
Target enrollment increased from 350 to 400
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 2 new sites: Providence, Rhode Island, London, United Kingdom
Added 1 new site: Darlinghurst, Australia
Added 85 new sites: Phoenix, Arizona, Los Angeles, California, Sacramento, California and 82 more
Eligibility criteria have been updated
Added 3 new sites: Aurora, Colorado, St Louis, Missouri, Philadelphia, Pennsylvania
Added 2 new sites: Macon, Georgia, Nagasaki, Japan
Reduced from 7 to 3 sites
Target enrollment decreased from 6 to 3
Added 10 new sites: Indianapolis, Indiana, Albany, New York, Verona, Italy and 7 more
Eligibility criteria have been updated
Added 5 new sites: Birmingham, Alabama, Brandon, Florida, Austin, Texas and 2 more
Added 1 new site: Oxford, United Kingdom
Reduced from 7 to 3 sites
Target enrollment decreased from 6 to 3
Added 10 new sites: Indianapolis, Indiana, Albany, New York, Verona, Italy and 7 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Expanded from 7 to 8 sites
Added 4 new sites: Chengdu, China, Nanchang, China, Suzhou, China and 1 more
Eligibility criteria have been updated
Added 1 new site: Kocaeli, Turkey (Türkiye)
Reduced from 35 to 30 sites
Target enrollment decreased from 259 to 97
Added 1 new site: Guaynabo, Puerto Rico
Added 8 new sites: Columbus, Ohio, Milwaukee, Wisconsin, Teplice, Czechia and 5 more
Added 2 new sites: Atlanta, Georgia, Cordova, Tennessee
Added 1 new site: Calgary, Canada
Eligibility criteria have been updated
Eligibility criteria have been updated
Expanded from 97 to 98 sites
Reduced from 47 to 45 sites
Target enrollment increased from 81 to 112
Added 1 new site: Qingdao, China
Eligibility criteria have been updated
Added 4 new sites: Madera, California, Gainesville, Florida, Córdoba, Argentina and 1 more
Added 18 new sites: Scottsdale, Arizona, Santa Monica, California, Centennial, Colorado and 15 more
Added 3 new sites: Buenos Aires, Argentina, Toronto, Canada, Trois-Rivières, Canada
Reduced from 32 to 30 sites
Reduced from 19 to 17 sites
Eligibility criteria have been updated
Added 1 new site: Richmond, Virginia
Target enrollment increased from 705 to 845
Eligibility criteria have been updated
Added 4 new sites: Pilar, Argentina, Santiago, Chile, Giessen, Germany and 1 more
Reduced from 130 to 120 sites
Added 2 new sites: Milan, Italy, Milan, Italy
Eligibility criteria have been updated
Added 3 new sites: Evanston, Illinois, Glenview, Illinois, Highland Park, Illinois
Reduced from 23 to 15 sites
Eligibility criteria have been updated
Target enrollment increased from 2323 to 2586
Added 3 new sites: Vitória, Brazil, Campinas, Brazil, Rio de Janeiro, Brazil
Added 3 new sites: Vitória, Brazil, Campinas, Brazil, Rio de Janeiro, Brazil
Eligibility criteria have been updated
Added 1 new site: Heeze, Netherlands
Added 9 new sites: Godoy Cruz, Argentina, Ribeirão Preto, Brazil, Copenhaen, Denmark and 6 more
Reduced from 152 to 141 sites
Added 4 new sites: Barranquilla, Colombia, Kobe, Japan, Newcastle upon Tyne, United Kingdom and 1 more
Added 3 new sites: Chevy Chase, Maryland, Hagerstown, Maryland, San Antonio, Texas
Added 34 new sites: Duarte, California, Upland, California, Aurora, Colorado and 31 more
Added 7 new sites: Kansas City, Kansas, Orangeburg, South Carolina, Conroe, Texas and 4 more
Reduced from 7 to 3 sites
Target enrollment decreased from 6 to 3
Added 10 new sites: Indianapolis, Indiana, Albany, New York, Verona, Italy and 7 more
Eligibility criteria have been updated
Added 2 new sites: Baltimore, Maryland, Charlotte, North Carolina
Added 1 new site: Buenos Aires, Argentina
Added 8 new sites: La Jolla, California, Hanover, Germany, Ankara, Turkey (Türkiye) and 5 more
Added 1 new site: Halle, Germany
Added 1 new site: New Hyde Park, New York
Expanded from 64 to 65 sites
Added 2 new sites: Charleston, South Carolina, Charleston, South Carolina
Eligibility criteria have been updated
Added 3 new sites: Bergamo, Italy, Pisa, Italy, Naples, Italy
Added 1 new site: Oxford, United Kingdom
Target enrollment decreased from 31 to 23
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment decreased from 320 to 251
Added 3 new sites: Winter Park, Florida, Wichita, Kansas, Vienna, Virginia
Added 3 new sites: Hradec Králové, Czechia, Bydgoszcz, Poland, Katowice, Poland
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 5 new sites: Palo Alto, California, Chicago, Illinois, Boston, Massachusetts and 2 more
Added 1 new site: Göttingen, Germany
Added 14 new sites: La Jolla, California, Denver, Colorado, New Haven, Connecticut and 11 more
Added 11 new sites: Boca Raton, Florida, Hialeah, Florida, Worcester, Massachusetts and 8 more
Eligibility criteria have been updated
Target enrollment decreased from 150 to 64
Added 27 new sites: Nanning, China, Chifeng, China, Xuzhou, China and 24 more
Added 2 new sites: Sun City, Arizona, Calicut, India
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Skokie, Illinois
Added 24 new sites: San Diego, California, Berlin, Germany, Dresden, Germany and 21 more
Added 2 new sites: Boise, Idaho, Iowa City, Iowa
Target enrollment decreased from 385 to 253
Target enrollment decreased from 150 to 110
Target enrollment decreased from 5000 to 3543
Eligibility criteria have been updated
Target enrollment decreased from 540 to 421
Added 14 new sites: Krasnodar, Russia, Krasnodar, Russia, Novosibirsk, Russia and 11 more
Eligibility criteria have been updated
Added 55 new sites: Miami, Florida, Miami, Florida, Chicago, Illinois and 52 more
Added 20 new sites: Tucson, Arizona, Beverly Hills, California, Kansas City, Kansas and 17 more
Eligibility criteria have been updated
Added 2 new sites: Rostock, Germany, Sheffield, United Kingdom
Added 1 new site: Oxford, United Kingdom
Eligibility criteria have been updated
Added 1 new site: Chicago, Illinois
Added 1 new site: Rochester, Minnesota
Added 1 new site: Newcastle upon Tyne, United Kingdom
Reduced from 281 to 212 sites
Target enrollment increased from 15 to 20
Eligibility criteria have been updated
Added 1 new site: San Antonio, Texas
Eligibility criteria have been updated
Added 3 new sites: Tübingen, Germany, Iași, Romania, Suwon, South Korea
Target enrollment decreased from 68 to 45
Added 4 new sites: Aurora, Colorado, Normal, Illinois, St Louis, Missouri and 1 more
Target enrollment increased from 15 to 18
Eligibility criteria have been updated
Added 5 new sites: Jeffersonville, Indiana, Canton, Ohio, Dallas, Texas and 2 more
Added 2 new sites: Phoenix, Arizona, Orlando, Florida
Eligibility criteria have been updated
Added 5 new sites: Riverside, California, Springfield, Missouri, New York, New York and 2 more
Added 17 new sites: Los Angeles, California, Torrance, California, Rochester, New York and 14 more
Added 13 new sites: Santa Barbara, California, Torrance, California, Kissimmee, Florida and 10 more
Added 20 new sites: Phoenix, Arizona, Los Angeles, California, San Francisco, California and 17 more
Added 41 new sites: Scottsdale, Arizona, Beverly Hills, California, Santa Barbara, California and 38 more
Eligibility criteria have been updated
Added 1 new site: Barcelona, Spain
Added 1 new site: Adelaide, Australia
Added 1 new site: New York, New York
Added 3 new sites: Tübingen, Germany, Iași, Romania, Suwon, South Korea
Eligibility criteria have been updated
Added 3 new sites: Brandon, Florida, Frisco, Texas, Krakow, Poland
Added 13 new sites: Novi, Michigan, Madison, Wisconsin, Bruges, Belgium and 10 more
Target enrollment increased from 100 to 402
Added 3 new sites: Palo Alto, California, Fitzroy, Australia, Aarhus, Denmark
Added 1 new site: Barcelona, Spain
Added 4 new sites: Jupiter, Florida, Houston, Texas, Adelaide, Australia and 1 more
Added 1 new site: Ottawa, Canada
Target enrollment increased from 34 to 69
Eligibility criteria have been updated
Added 1 new site: Hines, Illinois
Target enrollment decreased from 68 to 45
Eligibility criteria have been updated
Added 2 new sites: Birmingham, Alabama, Boston, Massachusetts
Added 2 new sites: Charlotte, North Carolina, Dallas, Texas
Added 8 new sites: Créteil, France, Garches, France, Grenoble, France and 5 more
Added 6 new sites: Philadelphia, Pennsylvania, CABA, Argentina, Ciudad Autonoma de Buenos Aires, Argentina and 3 more
Eligibility criteria have been updated
Added 1 new site: Fatih, Turkey (Türkiye)
Eligibility criteria have been updated
Added 10 new sites: Angers, France, Boulogne-sur-Mer, France, Créteil, France and 7 more
Target enrollment increased from 100 to 128
Added 7 new sites: Bron, France, Garches, France, Le Kremlin-Bicêtre, France and 4 more
Added 9 new sites: Fuzhou, China, Guangzhou, China, Guangzhou, China and 6 more
Eligibility criteria have been updated
Added 2 new sites: Kansas City, Kansas, Catania, Italy
Added 1 new site: Pozzilli, Italy
Target enrollment decreased from 68 to 45
Target enrollment increased from 200 to 500
Added 3 new sites: Sacramento, California, Shreveport, Louisiana, Nijmegen, Netherlands
Target enrollment increased from 600 to 700
Target enrollment decreased from 68 to 45
Added 4 new sites: Aurora, Colorado, Normal, Illinois, St Louis, Missouri and 1 more
Added 3 new sites: Bologna, Italy, Kaohsiung City, Taiwan, Leicester, United Kingdom
Added 2 new sites: Shenyang, China, Bari, Italy
Added 9 new sites: Box Hill, Australia, Montpellier, France, Rennes, France and 6 more
Added 1 new site: Farmington, Connecticut
Eligibility criteria have been updated
Added 1 new site: Denison, Texas
Added 21 new sites: Buenos Aires, Argentina, Antwerp, Belgium, Liège, Belgium and 18 more
Added 10 new sites: Newport Beach, California, Palm Springs, California, Redding, California and 7 more
Added 3 new sites: Metairie, Louisiana, Albany, New York, Summerville, South Carolina
Added 26 new sites: Birmingham, Alabama, Little Rock, Arkansas, Atlanta, Georgia and 23 more
Target enrollment decreased from 40 to 3
Added 3 new sites: Westmead, Australia, Gümligen, Switzerland, Cardiff, United Kingdom
Target enrollment increased from 12 to 21
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment decreased from 130 to 65
Eligibility criteria have been updated
Added 1 new site: Athens, Greece
Added 4 new sites: New Brunswick, New Jersey, Albuquerque, New Mexico, Tulsa, Oklahoma and 1 more
Added 1 new site: Calgary, Canada
Added 4 new sites: Chesterfield, Missouri, Wilmington, North Carolina, Cincinnati, Ohio and 1 more
Added 1 new site: Philadelphia, Pennsylvania
Eligibility criteria have been updated
Added 2 new sites: Copenhagen, Denmark, Odense C, Denmark
Added 2 new sites: Villejuif, France, Bologna, Italy
Added 2 new sites: Lone Tree, Colorado, Suwon, South Korea
Target enrollment decreased from 55 to 34
Target enrollment increased from 18 to 27
Eligibility criteria have been updated
Added 1 new site: Charlotte, North Carolina
Added 1 new site: Phoenix, Arizona
Added 3 new sites: West Allis, Wisconsin, South Brisbane, Australia, Clayton, Australia
Added 8 new sites: Colorado Springs, Colorado, Wheaton, Illinois, Box Hill, Australia and 5 more
Added 12 new sites: Godoy Cruz, Argentina, Rosario, Argentina, Brussels, Belgium and 9 more
Added 3 new sites: Tucson, Arizona, Raleigh, North Carolina, Dallas, Texas
Added 3 new sites: Glendale, Arizona, Doral, Florida, Miami, Florida
Added 6 new sites: Chicago, Illinois, Durham, North Carolina, Philadelphia, Pennsylvania and 3 more
Added 1 new site: Charleston, South Carolina
Added 14 new sites: Tucson, Arizona, Oakland, California, Fort Myers, Florida and 11 more
Eligibility criteria have been updated
Added 13 new sites: Hefei, China, Beijing, China, Fuzhou, China and 10 more
Added 1 new site: Portland, Oregon
Added 3 new sites: Belfast, United Kingdom, Frimley, United Kingdom, Manchester, United Kingdom
Added 46 new sites: Riverside, California, Sutherland, Australia, Sydney, Australia and 43 more
Eligibility criteria have been updated
Added 1 new site: Asheville, North Carolina
Added 5 new sites: Huntsville, Alabama, Chicago, Illinois, New York, New York and 2 more
Added 3 new sites: Sacramento, California, Lodz, Poland, Pamplona, Spain
Added 1 new site: Sagamihara, Japan
Added 1 new site: Barcelona, Spain
Reduced from 180 to 177 sites
Added 4 new sites: Jupiter, Florida, Houston, Texas, Adelaide, Australia and 1 more
Added 1 new site: Redwood City, California
Added 2 new sites: Durham, North Carolina, Montreal, Canada
Added 4 new sites: Duarte, California, Washington D.C., District of Columbia, Ann Arbor, Michigan and 1 more
Target enrollment decreased from 460 to 408
Added 4 new sites: Skokie, Illinois, Winchester, Virginia, Minato-ku, Japan and 1 more
Added 1 new site: Montreal, Canada
Added 7 new sites: Hot Springs, Arkansas, Indianapolis, Indiana, Kansas City, Missouri and 4 more
Added 2 new sites: Milwaukee, Wisconsin, Kobe, Japan
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 13 new sites: Centennial, Colorado, Miami Lakes, Florida, New York, New York and 10 more
Added 3 new sites: Mainz, Germany, Barcelona, Spain, Madrid, Spain
Added 32 new sites: Busan, South Korea, Busan, South Korea, Busan, South Korea and 29 more
Eligibility criteria have been updated
Added 2 new sites: Cambridge, United Kingdom, London, United Kingdom
Reduced from 27 to 21 sites
Added 1 new site: Montreal, Canada
Moved from Phase 1, Phase 2 to Phase 2
Added 5 new sites: Gainesville, Florida, Graz, Austria, Hiroshima, Japan and 2 more
Added 3 new sites: Bordeaux, France, Créteil, France, Le Kremlin-Bicêtre, France
Added 4 new sites: Santiago, Chile, Cologne, Germany, Bialystok, Poland and 1 more
Eligibility criteria have been updated
Added 1 new site: Augusta, Georgia
Added 4 new sites: Serdang, Malaysia, Ankara, Turkey (Türkiye), Hanoi, Vietnam and 1 more
Added 1 new site: El Paso, Texas
Added 32 new sites: Tampa, Florida, Kansas City, Kansas, Fall River, Massachusetts and 29 more
Added 18 new sites: Munich, Germany, Halle, Germany, München, Germany and 15 more
Added 4 new sites: Seattle, Washington, Vancouver, Canada, Turin, Italy and 1 more
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 1 new site: Dallas, Texas
Target enrollment increased from 66 to 84
Eligibility criteria have been updated
Eligibility criteria have been updated
Target enrollment decreased from 87 to 40
Added 14 new sites: Bergamo, Italy, Catania, Italy, Catanzaro, Italy and 11 more
Eligibility criteria have been updated
Added 1 new site: Grenoble, France
Target enrollment decreased from 60 to 21
Added 8 new sites: Duarte, California, Atlanta, Georgia, Chicago, Illinois and 5 more
Added 32 new sites: Caulfield South, Australia, Sydney, Australia, Southport, Australia and 29 more
Added 2 new sites: Baltimore, Maryland, Worcester, Massachusetts
Added 1 new site: Phoenix, Arizona
Added 1 new site: London, United Kingdom
Eligibility criteria have been updated
Eligibility criteria have been updated
Added 2 new sites: Aurora, Colorado, New York, New York
Added 2 new sites: New York, New York, Philadelphia, Pennsylvania
Added 3 new sites: Palo Alto, California, New York, New York, Philadelphia, Pennsylvania
Added 5 new sites: Aurora, Colorado, Grand Rapids, Michigan, Columbus, Ohio and 2 more