Amyotrophic Lateral Sclerosis Clinical Trials Near Me
As of October 12, 2026, 224 Amyotrophic Lateral Sclerosis clinical trials are recruiting or about to open (173 recruiting now, 51 opening soon). 83 of them have at least 1 open site in the United States, across 33 states. Enter your ZIP code to see which are closest to you.
Also on Trial Friend:Amyotrophic Lateral Sclerosis pageMatch Me
All 173 Amyotrophic Lateral Sclerosis trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- ASSESS ALL ALS StudyUniversity of Alabama Birmingham, Birmingham, Alabama; Barrow Neurological Institute, Phoenix, Arizona; University of California, Irvine, Irvine, California and 31 more sitesRecruitingAges 18+Run by St. Joseph's Hospital and Medical Center, Phoenix
- PREVENT ALL ALS StudyUniversity of Alabama Birmingham, Birmingham, Alabama; Barrow Neurological Institute, Phoenix, Arizona; University of California San Diego, La Jolla, California and 28 more sitesRecruitingAges 18+Run by St. Joseph's Hospital and Medical Center, Phoenix
- ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)University of Alabama Birmingham, Birmingham, Alabama; University of California, Los Angeles, Los Angeles, California; University of California, San Diego, San Diego, California and 21 more sitesRecruitingAges 18+Run by Mayo Clinic
- Study of COYA 302 for the Treatment of ALSBarrow Neurological Institute, Phoenix, Arizona; Cedars-Sinai Medical Center, Los Angeles, California; California Pacific Medical Center, San Francisco, California and 18 more sitesRecruitingPhase 2/3Ages 18 to 80Run by Coya Therapeutics
- Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALSBarrow Neurological Institute, Phoenix, Arizona; California Pacific Medical Center, San Francisco, California; University of Colorado CU Anschutz Neurology, Aurora, Colorado and 15 more sitesRecruitingPhase 3Ages 18 to 80Run by Prilenia
- Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral SclerosisZydus US015, La Jolla, California; Zydus US008, Orange, California; Zydus US013, San Francisco, California and 12 more sitesRecruitingPhase 2Ages 18+Run by Zydus Therapeutics Inc.
- ALS/MND Natural History Study Data RepositoryLoma Linda University Health, Loma Linda, California; Kaiser Permanente, Los Angeles, California; University of Florida, Gainesville, Florida and 11 more sitesRecruitingAges 18 to 90Run by Massachusetts General Hospital
- AMX0114 in Adult Participants With Amyotrophic Lateral SclerosisUniversity of California, San Diego, La Jolla, California; Georgetown University Hospital Pasquerilla Healthcare Center, Washington D.C., District of Columbia; University of Florida, Gainesville, Florida and 7 more sitesRecruitingPhase 1Ages 18+Run by Amylyx Pharmaceuticals Inc.
- Clinical Procedures to Support Research in ALSUniversity of California, Irvine, Irvine, California; Stanford University, Palo Alto, California; California Pacific Medical Center, San Francisco, California and 7 more sitesRecruitingAges 18+Run by University of Miami
- Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home MeasuresBarrow Neurological Institute, Phoenix, Arizona; University of California San Diego, San Diego, California; Georgetown University, Georgetown, District of Columbia and 7 more sitesRecruitingAges 18+Run by Target ALS Foundation, Inc.
- A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)USA004, La Jolla, California; USA002, Palo Alto, California; USA003, Baltimore, Maryland and 4 more sitesRecruitingPhase 1Ages 18 to 79Run by Insmed Gene Therapy LLC
- Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?Mayo Clinic Scottsdale, Scottsdale, Arizona; Mayo Clinic Jacksonville, Jacksonville, Florida; Massachusetts General Hospital, Boston, Massachusetts and 4 more sitesRecruitingAges 18+Run by Trustees of Dartmouth College
- Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALSSt Joseph's Hospital and medical Center - Barrow Neurological Institute, Phoenix, Arizona; University of California San Diego Medical Center, San Diego, California; Mayo Clinic in Florida, Jacksonville, Florida and 4 more sitesRecruitingPhase 1/2Ages 18+Run by Vector Y Therapeutics
- A Study of Ranolazine in ALSUniversity of California, San Francisco, San Francisco, California; Mayo Clinic Florida, Jacksonville, Florida; University of Kansas Medical Center, Fairway, Kansas and 3 more sitesRecruitingPhase 2Ages 18+Run by Swathy Chandrashekhar, MBBS
- BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With TetraplegiaUniversity of California, Davis, Sacramento, California; Stanford University School of Medicine, Stanford, California; Emory University School of Medicine, Atlanta, Georgia and 3 more sitesRecruitingAges 18 to 80Run by Leigh R. Hochberg, MD, PhD.
- Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS PatientsUniversity of Alabama at Birmingham, Birmingham, Alabama; University of Southern California, Los Angeles, California; University of Kentucky, Lexington, Kentucky and 3 more sitesRecruitingPhase 3Ages 18 to 81Run by AB Science
- EIM Via the Myolex mScan as an ALS BiomarkerBarrow Neurological Institute, Phoenix, Arizona; Massachusetts General Hospital, Boston, Massachusetts; Beth Israel Deaconess Medical Center, Boston, Massachusetts and 3 more sitesRecruitingAges 18+Run by Beth Israel Deaconess Medical Center
- INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility StudyMayo Clinic, Jacksonville, Florida; University of Buffalo Neurosurgery, Buffalo, New York; Mount Sinai Hospital, New York, New York and 2 more sitesRecruitingAges 22+Run by Synchron, Inc.
- PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALSHonor Health Neurology - Bob Bove Neuroscience Institute, Scottsdale, Arizona; University of California San Diego, La Jolla, California; Sutter Health - California Pacific Medical Center Research Institute, San Francisco, California and 2 more sitesRecruitingPhase 2Ages 18 to 75Run by PhenoNet, Inc.
- Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)University of California, Davis, Sacramento, California; Massachusetts General Hospital, Boston, Massachusetts; University of Michigan, Ann Arbor, MichiganRecruitingAges 22 to 75Run by Paradromics
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Where Amyotrophic Lateral Sclerosis trials are recruiting in the US
The US cities with the most Amyotrophic Lateral Sclerosis trials recruiting are Boston, Massachusetts (24), Jacksonville, Florida (15), Philadelphia, Pennsylvania (15), Baltimore, Maryland (13) and New York, New York (11), counting trials with at least 1 open site in each city.
Hospitals that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Amyotrophic Lateral Sclerosis, even if no trial fits you.
- Massachusetts General Hospital
- Beth Israel Deaconess Medical Center
- Massachusetts General Brigham
- and 7 more
- Mayo Clinic
- Mayo Clinic Florida
- Mayo Clinic in Florida
- and 1 more
- University of Pennsylvania
- Temple University
- Neuroscience Department at LKSM at Temple University
- and 9 more
- Johns Hopkins University
- John Hopkins University
- Johns Hopkins Medicine
- and 6 more
- Columbia University
- Columbia University Medical Center ALS Center
- Eleanor and Lou Gehrig ALS Center at Columbia University
- and 5 more
- California Pacific Medical Center
- University of California, San Francisco
- Sutter Health - California Pacific Medical Center Research Institute
- and 3 more
- Northwestern University
- Northwestern
- Northwestern Medicine
- and 3 more
- Barrow Neurological Institute
- Barrow Neurological Institute (St. Joseph's)
- St Joseph's Hospital and medical Center - Barrow Neurological Institute
States with at least 1 open site: Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Nebraska, New Hampshire, New York, North Carolina, Ohio, Oregon, Pennsylvania, Rhode Island, Tennessee, Texas, Utah, Virginia, Washington, Wisconsin.
Questions about finding an Amyotrophic Lateral Sclerosis trial near you
Are there Amyotrophic Lateral Sclerosis clinical trials near me?
As of October 12, 2026, 224 Amyotrophic Lateral Sclerosis clinical trials are recruiting or about to open (173 recruiting now, 51 opening soon). 83 of them have at least 1 open site in the United States, across 33 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Amyotrophic Lateral Sclerosis clinical trial sites?
As of October 12, 2026, recruiting Amyotrophic Lateral Sclerosis trials list open sites in 33 states. The US cities with the most Amyotrophic Lateral Sclerosis trials recruiting are Boston, Massachusetts (24), Jacksonville, Florida (15), Philadelphia, Pennsylvania (15), Baltimore, Maryland (13) and New York, New York (11), counting trials with at least 1 open site in each city.
What if there is no Amyotrophic Lateral Sclerosis trial near me?
Some trials pay for or reimburse travel and lodging, and a few send staff or use local labs so fewer visits happen at the study site, so ask the study contact before ruling a trial out. You can also sign up on this page to get an email when an Amyotrophic Lateral Sclerosis trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Amyotrophic Lateral Sclerosis: Qalsody (tofersen), Rilutek (riluzole), Radicava (edaravone).
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of October 12, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out.