Also on Trial Friend:Angelman Syndrome pageMatch Me
All 10 Angelman Syndrome trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- Angelman Syndrome Natural History StudyMost sites in California, Colorado and GeorgiaRecruitingBoston Children's Hospital8US sites
7 states - BEACON - Phase III Clinical Study of Rugonersen in Angelman Syndrome.Most sites in California, Colorado and FloridaRecruitingPhase 3Ages 1-50OHB Pediatrics7US sites
6 states - A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman SyndromeMost sites in California, Illinois and MassachusettsRecruitingPhase 1/2Ages 4-50MavriX Bio3US sites
3 states - A Natural History Study of Angelman SyndromeOnly in MassachusettsRecruitingAges 1+Massachusetts General Hospital1US site
- CHAMPION: A Study to Evaluate the Efficacy and Safety of Obudanersen (ION582) in Children and Adults With Angelman Syndrome (AS)Only in North CarolinaRecruitingPhase 3Ages 2-50Ionis Pharmaceuticals1US site
- IDMet (RaDiCo Cohort) (RaDiCo-IDMet)RecruitingInstitut National de la Santé Et de la Recherche Médicale, FranceNo US site yet
- Natural History Study for Patients With Angelman SyndromeRecruitingCentre Hospitalier Universitaire de LiegeNo US site yet
- Structural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With EpilepsyRecruitingAges 6-75IRCCS Eugenio MedeaNo US site yet
- The Global Angelman Syndrome RegistryRecruitingFoundation for Angelman Syndrome Therapeutics, AustraliaNo US site yet
- Use of Eye Tracking to Study Social Perception Abnormalities in Children With Angelman SyndromeRecruitingAges 3-17Assistance Publique - Hôpitaux de ParisNo US site yet
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Who runs the Angelman Syndrome trials in the US, and what stage they are in
Of the 5 Angelman Syndrome trials with a US site, 2 are in Phase 3, the last stage before a company can ask the FDA for approval. One more is an earlier Phase 1 or 2 test of safety and dosing. The remaining 2 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 3 of them, and universities, hospitals, foundations and government groups run 2. The most recently listed one first appeared on ClinicalTrials.gov on August 24, 2026.
Angelman Syndrome trials in the US, state by state
All 5 Angelman Syndrome trials with a US site accept children under 18. Their open sites are in 8 states, most often California, Illinois and Massachusetts. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
US hospitals running the most Angelman Syndrome trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Angelman Syndrome.
- Boston Children's HospitalBoston, Massachusetts2 trials
- Cedars-Sinai Medical CenterLos Angeles, California2 trials
- Cedars-Sinai Guerin Children'sLos Angeles, California1 trial
- Children's Hospital ColoradoAurora, Colorado1 trial
- Children's Hospital Colorado, Anschutz Medical CampusAurora, Colorado1 trial
- Emory University School of MedicineAtlanta, Georgia1 trial
- MGH Lurie Center for AutismLexington, Massachusetts1 trial
- Monroe Carell Jr. Children's Hospital at VanderbiltNashville, Tennessee1 trial
- Nicklaus Children's HospitalMiami, Florida1 trial
- Rady Children's HospitalSan Diego, California1 trial
Help getting to an Angelman Syndrome trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding an Angelman Syndrome trial near you
Are there Angelman Syndrome clinical trials near me?
As of November 13, 2026, 10 Angelman Syndrome clinical trials are recruiting. In the US, 5 of them have at least 1 open site, across 8 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Angelman Syndrome clinical trial sites?
Recruiting Angelman Syndrome trials list open sites in California, Colorado, Florida, Georgia, Illinois, Massachusetts, North Carolina and Tennessee.
Are there Angelman Syndrome trials for children near me?
All 5 Angelman Syndrome trials with a US site accept children under 18. Their open sites are in 8 states, most often California, Illinois and Massachusetts. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to an Angelman Syndrome clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Angelman Syndrome trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when an Angelman Syndrome trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.