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All 11 Hereditary Angioedema trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- STOP-HAE: A Phase 3 Study of ADX-324 in HAEMost sites in California, Ohio and ArizonaRecruitingPhase 3Ages 18+ADARx Pharmaceuticals17US sites
12 states - Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)Most sites in Ohio, California and MarylandRecruitingPhase 3Ages 18+ADARx Pharmaceuticals15US sites
11 states - Donidalorsen Treatment in Children With Hereditary AngioedemaMost sites in Ohio, California and FloridaRecruitingPhase 3Ages 2-11Ionis Pharmaceuticals8US sites
7 states - A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)Most sites in Arizona, Florida and KentuckyRecruitingAges 12+CSL Behring4US sites
4 states - Angioedema Biomarker Research StudyOnly in MarylandRecruitingAges 12-75Foundation For Rare Disease Research1US site
- Oral Deucrictibant for Prophylactic and Acute Treatment in Hereditary Angioedema PatientsOnly in MarylandRecruitingPhase 1/2Ages 18-75Institute for Asthma and Allergy1US site
- Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL)Only in ColoradoRecruitingPhase 4Ages 12+KalVista Pharmaceuticals1US site
- A Study of Takhzyro in Teenagers and Adults With Hereditary Angioedema (HAE) in South KoreaRecruitingAges 12+TakedaNo US site yet
- A Study to Learn About the C1-Inhibitor Function as Diagnosis for Hereditary AngioedemaRecruitingAges 12+TakedaNo US site yet
- Institutional Registry of Rare DiseasesRecruitingHospital Italiano de Buenos AiresNo US site yet
- Real-life Ecological Momentary Assessment of Lived Burden in Hereditary AngioEdemaRecruitingAges 18+Istituti Clinici Scientifici Maugeri SpANo US site yet
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Who runs the Hereditary Angioedema trials in the US, and what stage they are in
Of the 7 Hereditary Angioedema trials with a US site, 3 are in Phase 3, the last stage before a company can ask the FDA for approval. One more is an earlier Phase 1 or 2 test of safety and dosing. One is a Phase 4 study of an already approved treatment. The remaining 2 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 5 of them, and universities, hospitals, foundations and government groups run 2. ADARx Pharmaceuticals runs the most, with 2. The most recently listed one first appeared on ClinicalTrials.gov on June 17, 2026.
Hereditary Angioedema trials in the US, state by state
Of the 7 Hereditary Angioedema trials with a US site, 4 accept children under 18. Their open sites are in 12 states, most often Florida, Arizona and California. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 6 states
US hospitals running the most Hereditary Angioedema trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Hereditary Angioedema.
- Family Allergy and AsthmaLouisville, Kentucky1 trial
- Institute For Asthma & AllergyWheaton, Maryland1 trial
- Institute for Asthma and Allergy Clinical ResearchWheaton, Maryland1 trial
- Medical Research of ArizonaPhoenix, Arizona1 trial
- Riverside Medical Group, BellevilleBelleville, New Jersey1 trial
- Sirven and AssociatesMiami, Florida1 trial
Help getting to a Hereditary Angioedema trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Hereditary Angioedema trial near you
Are there Hereditary Angioedema clinical trials near me?
As of November 13, 2026, 11 Hereditary Angioedema clinical trials are recruiting now and 3 are not yet recruiting. In the US, 7 of them have at least 1 open site, across 16 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Hereditary Angioedema clinical trial sites?
Recruiting Hereditary Angioedema trials list open sites in 16 states. Florida, Maryland and Arizona have the most, and the table on this page lists every state.
Are there Hereditary Angioedema trials for children near me?
Of the 7 Hereditary Angioedema trials with a US site, 4 accept children under 18. Their open sites are in 12 states, most often Florida, Arizona and California. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Hereditary Angioedema clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Hereditary Angioedema trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Hereditary Angioedema trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Hereditary Angioedema: Andembry (garadacimab), Dawnzera (donidalorsen), Ekterly (sebetralstat), Orladeyo (berotralstat), Takhzyro (lanadelumab), Berinert / Cinryze / Haegarda (c1 esterase inhibitor (human)), Danazol, Firazyr (icatibant acetate) and 1 more on the disease page.
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.