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All 6 Severe Combined Immunodeficiency trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan ConditioningMost sites in California, Georgia and MassachusettsRecruitingPhase 1/2Ages 0-5David Williams4US sites
4 states - Autologous Gene Therapy for Artemis-Deficient SCIDOnly in CaliforniaRecruitingPhase 1/2Ages 2 Months+University of California, San Francisco1US site
- Genetic Basis of ImmunodeficiencyOnly in MarylandRecruitingAges 6 Months-99National Heart, Lung, and Blood Institute (NHLBI)1US site
- Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)Only in MarylandRecruitingPhase 1/2Ages 2-50National Institute of Allergy and Infectious Diseases (NIAID)1US site
- Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE)RecruitingPhase 1/2Up to age 47 MonthsAssistance Publique - Hôpitaux de ParisNo US site yet
- The Experience of Screening for SCIDRecruitingAges 18+King's College LondonNo US site yet
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Who runs the Severe Combined Immunodeficiency trials in the US, and what stage they are in
None of the 4 Severe Combined Immunodeficiency trials with a US site is in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 3 of them. The last one has no drug phase, such as a study that follows people over time or tests a device or a way of giving care. Universities, hospitals, foundations and government groups run all of them, with no company leading one. The most recently listed one first appeared on ClinicalTrials.gov on May 29, 2018.
Severe Combined Immunodeficiency trials in the US, state by state
All 4 Severe Combined Immunodeficiency trials with a US site accept children under 18. Their open sites are in 5 states, most often California, Maryland and Georgia. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
US hospitals running the most Severe Combined Immunodeficiency trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Severe Combined Immunodeficiency.
- National Institutes of Health Clinical CenterBethesda, Maryland2 trials
- Boston Childrens HospitalBoston, Massachusetts1 trial
- Cincinnati Children's Hospital Medical CenterCincinnati, Ohio1 trial
- Emory University/Childrens Healthcare of AtlantaAtlanta, Georgia1 trial
- Mattel Children's Hospital - UCLALos Angeles, California1 trial
- University of California, San Francisco (UCSF) Children's HospitalSan Francisco, California1 trial
Help getting to a Severe Combined Immunodeficiency trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Severe Combined Immunodeficiency trial near you
Are there Severe Combined Immunodeficiency clinical trials near me?
As of November 13, 2026, 6 Severe Combined Immunodeficiency clinical trials are recruiting now and 4 are not yet recruiting. In the US, 4 of them have at least 1 open site, across 5 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Severe Combined Immunodeficiency clinical trial sites?
Recruiting Severe Combined Immunodeficiency trials list open sites in California, Georgia, Maryland, Massachusetts and Ohio.
Are there Severe Combined Immunodeficiency trials for children near me?
All 4 Severe Combined Immunodeficiency trials with a US site accept children under 18. Their open sites are in 5 states, most often California, Maryland and Georgia. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Severe Combined Immunodeficiency clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Severe Combined Immunodeficiency trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Severe Combined Immunodeficiency trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Severe Combined Immunodeficiency: Immune globulin (immune globulin (human)), Revcovi (elapegademase-lvlr).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.