Also on Trial Friend:Systemic Mastocytosis pageMatch Me
All 10 Systemic Mastocytosis trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- (HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic MastocytosisMost sites in California, New York and AlabamaRecruitingPhase 2/3Ages 18+Blueprint Medicines15US sites
12 states - (Apex) Bezuclastinib in Patients With Advanced Systemic MastocytosisMost sites in California, Arizona and GeorgiaRecruitingPhase 2Ages 18+Cogent Biosciences9US sites
7 states - An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM)Most sites in Colorado, Illinois and MarylandRecruitingAges 18+Blueprint Medicines7US sites
7 states - Avapritinib With Decitabine in Patients With SM-AHNMost sites in Arizona, California and FloridaRecruitingPhase 1Ages 18+H. Lee Moffitt Cancer Center and Research Institute7US sites
7 states - Angioedema Biomarker Research StudyOnly in MarylandRecruitingAges 12-75Foundation For Rare Disease Research1US site
- A Non-Interventional Study in Participants With Indolent Systemic Mastocytosis (ISM) in GermanyRecruitingAges 18+Blueprint MedicinesNo US site yet
- Avapritinib Rollover StudyRecruitingPhase 4Blueprint MedicinesNo US site yet
- Mastocytosis From Pediatric Age to Adulthood: Local Registry of Cutaneous and Systemic MastocytosisRecruitingAges 6+Fondazione IRCCS Policlinico San Matteo di PaviaNo US site yet
- New Italian Mastocytosis RegistryRecruitingAges 18+Associazione Rete Italiana MastocitosiNo US site yet
- Peripheral Blood KIT-D816V Mutation in Adult Systemic MastocytosisRecruitingAges 18+The First Affiliated Hospital of Soochow UniversityNo US site yet
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Who runs the Systemic Mastocytosis trials in the US, and what stage they are in
Of the 7 Systemic Mastocytosis trials with a US site, 1 is in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 3 of them. The remaining 3 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 3 of them, and universities, hospitals, foundations and government groups run 4. Blueprint Medicines runs the most, with 2. The most recently listed one first appeared on ClinicalTrials.gov on September 14, 2026.
Systemic Mastocytosis trials in the US, state by state
Of the 7 Systemic Mastocytosis trials with a US site, 2 accept children under 18. Their open sites are in Maryland and Washington. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 9 states
US hospitals running the most Systemic Mastocytosis trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Systemic Mastocytosis.
- Dana-Farber Cancer InstituteBoston, Massachusetts2 trials
- Mayo ClinicRochester, Minnesota2 trials
- Brigham and Women's Allergy and Clinical Immunology, Mass General Brigham Healthcare Center (Chestnut Hill)Chestnut Hill, Massachusetts1 trial
- Brigham and Women's HospitalBoston, Massachusetts1 trial
- City of Hope Comprehensive Cancer CenterDuarte, California1 trial
- Columbia University Medical CenterNew York, New York1 trial
- David Geffen School of Medicine at UCLALos Angeles, California1 trial
- Duke Asthma, Allergy and Airway CenterDurham, North Carolina1 trial
- Fred Hutch/University of Washington Cancer ConsortiumSeattle, Washington1 trial
- Huntsman Cancer Institute - University of Utah HealthSalt Lake City, Utah1 trial
Help getting to a Systemic Mastocytosis trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Systemic Mastocytosis trial near you
Are there Systemic Mastocytosis clinical trials near me?
As of November 13, 2026, 10 Systemic Mastocytosis clinical trials are recruiting now and 2 are not yet recruiting. In the US, 7 of them have at least 1 open site, across 19 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Systemic Mastocytosis clinical trial sites?
Recruiting Systemic Mastocytosis trials list open sites in 19 states. Massachusetts, Utah and California have the most, and the table on this page lists every state.
Are there Systemic Mastocytosis trials for children near me?
Of the 7 Systemic Mastocytosis trials with a US site, 2 accept children under 18. Their open sites are in Maryland and Washington. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Systemic Mastocytosis clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Systemic Mastocytosis trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Systemic Mastocytosis trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Systemic Mastocytosis: Ayvakit (avapritinib), Rydapt (midostaurin), Cimetidine, Gastrocrom (cromolyn sodium (oral concentrate)), Gleevec (imatinib mesylate), Omeprazole.
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.