Also on Trial Friend:Myelofibrosis pageMatch Me
All 84 Myelofibrosis trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryMost sites in California, New York and MarylandRecruitingMassive Bio67US sites
40 states - Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to RuxolitinibMost sites in Ohio, New York and North CarolinaRecruitingPhase 3Ages 18+Kartos Therapeutics58US sites
28 states - A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)Most sites in Florida, California and KansasRecruitingPhase 2Ages 18+National Cancer Institute (NCI)32US sites
13 states - A Study of Oral Nuvisertib (TP-3654) in Patients With MyelofibrosisMost sites in New York, California and FloridaRecruitingPhase 1/2Ages 18+Sumitomo Pharma America30US sites
23 states - A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking RuxolitinibMost sites in Florida, Pennsylvania and TexasRecruitingPhase 3Ages 18+Takeda29US sites
18 states - Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and AnemiaMost sites in California, Florida and New YorkRecruitingPhase 1/2Ages 18+Disc Medicine29US sites
19 states - A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)Most sites in Florida, Texas and New YorkRecruitingPhase 3Ages 18+Novartis Pharmaceuticals23US sites
15 states - A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)Most sites in Massachusetts, New York and OhioRecruitingPhase 1Ages 18+Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company13US sites
10 states - A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell TransplantationMost sites in California, Alabama and FloridaRecruitingPhase 2Ages 18-66Center for International Blood and Marrow Transplant Research13US sites
12 states - A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative NeoplasmsMost sites in Florida, California and TennesseeRecruitingPhase 1Ages 18+Prelude Therapeutics Incorporated11US sites
7 states - A Study of Ruxolitinib in Combination With Ulixertinib in People With MyelofibrosisMost sites in New York, New Jersey and MassachusettsRecruitingPhase 1/2Ages 18+Memorial Sloan Kettering Cancer Center9US sites
4 states - Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)Most sites in New York, Ohio and FloridaRecruitingPhase 2Ages 18+Icahn School of Medicine at Mount Sinai9US sites
5 states - Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.Most sites in Ohio, Illinois and MassachusettsRecruitingPhase 1Ages 13+Newave Pharmaceutical8US sites
6 states - A Study of Ruxolitinib in Combination With Abemaciclib for the Treatment of MyelofibrosisMost sites in New York and New JerseyRecruitingPhase 1Ages 18+Memorial Sloan Kettering Cancer Center7US sites
2 states - A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate ThrombocytopeniaMost sites in California, Maryland and New YorkRecruitingPhase 2Ages 18+Karyopharm Therapeutics7US sites
7 states - Pacritinib Effectiveness in Real-world SettingsMost sites in Connecticut, Florida and OhioRecruitingAges 18+Swedish Orphan Biovitrum5US sites
5 states - Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent MyelofibrosisMost sites in Michigan, New York and TennesseeRecruitingPhase 2Ages 18+GlaxoSmithKline5US sites
5 states - A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)Most sites in Michigan, North Carolina and OhioRecruitingPhase 3Ages 18+Merck Sharp & Dohme4US sites
4 states - Leading in MPNs Beyond Ruxolitinib in Combo With T-RegsMost sites in New York, California and TexasRecruitingPhase 1Ages 18+Cellenkos4US sites
3 states - Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to RuxolitinibMost sites in Ohio, Alabama and TexasRecruitingPhase 1/2Ages 18+Telios Pharma4US sites
3 states
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Who runs the Myelofibrosis trials in the US, and what stage they are in
Of the 55 Myelofibrosis trials with a US site, 4 are in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 45 of them. The remaining 6 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 16 of them, and universities, hospitals, foundations and government groups run 39. The sponsors with the most are John Mascarenhas (3), M.D. Anderson Cancer Center (3) and Memorial Sloan Kettering Cancer Center (3). The most recently listed one first appeared on ClinicalTrials.gov on November 13, 2026.
Myelofibrosis trials in the US, state by state
Of the 55 Myelofibrosis trials with a US site, 6 accept children under 18. Their open sites are in 40 states, most often Minnesota, Alabama and Illinois. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 35 states
US hospitals running the most Myelofibrosis trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Myelofibrosis.
- Memorial Sloan Kettering Cancer CenterNew York, New York8 trials
- MD Anderson Cancer CenterHouston, Texas7 trials
- Icahn School of Medicine at Mount SinaiNew York, New York6 trials
- Cleveland ClinicCleveland, Ohio5 trials
- Moffitt Cancer CenterTampa, Florida5 trials
- The Ohio State UniversityColumbus, Ohio4 trials
- Dana Farber Cancer InstituteBoston, Massachusetts3 trials
- Emory UniversityAtlanta, Georgia3 trials
- Fred Hutch/University of Washington Cancer ConsortiumSeattle, Washington3 trials
- Massachusetts General HospitalBoston, Massachusetts3 trials
Help getting to a Myelofibrosis trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Corporate Angel Network
- Puts cancer patients in empty seats on business jets for treatment, second opinions and clinical trials. Open to anyone with cancer who can walk and travel without medical help, and it does not check income.
- American Cancer Society Hope Lodge
- Offers a free place to stay at 31 Hope Lodge locations for people getting cancer treatment far from home. People facing cancer and their caregivers, when treatment is far from home.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Myelofibrosis trial near you
Are there Myelofibrosis clinical trials near me?
As of November 13, 2026, 84 Myelofibrosis clinical trials are recruiting now and 17 are not yet recruiting. In the US, 55 of them have at least 1 open site, across 44 states and Washington, DC. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Myelofibrosis clinical trial sites?
Recruiting Myelofibrosis trials list open sites in 44 states and Washington, DC. New York, California and Texas have the most, and the table on this page lists every state.
Are there Myelofibrosis trials for children near me?
Of the 55 Myelofibrosis trials with a US site, 6 accept children under 18. Their open sites are in 40 states, most often Minnesota, Alabama and Illinois. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Myelofibrosis clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights, and Corporate Angel Network flies cancer patients for free.
What if there is no Myelofibrosis trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Myelofibrosis trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Myelofibrosis: Ojjaara (momelotinib), Vonjo (pacritinib), Inrebic (fedratinib hydrochloride), Jakafi (ruxolitinib).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.
