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All 18 Wilson Disease trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- A Study of the Safety and Efficacy of Prime Editing (PM577) in Participants With Wilson Disease (WD)Most sites in Connecticut, Illinois and TexasRecruitingPhase 1/2Ages 12+Prime Medicine3US sites
3 states - Natural History of Wilson DiseaseMost sites in Connecticut, Florida and TexasRecruitingYale University3US sites
3 states - Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients.Most sites in Colorado, Connecticut and MichiganRecruitingPhase 3Ages 8+Orphalan3US sites
3 states - Off Treatment Urinary Copper Excretion in Wilson Disease, Pilot StudyOnly in ConnecticutRecruitingAges 18+Yale University1US site
- A Clinical Study on the Treatment of Wilson Disease With ATP7B mRNA/LNP (DSL101)RecruitingEarly Phase 1Ages 18+DSciLab Co.No US site yet
- A Clinical Study to Evaluate the Safety and Efficacy of LY-M003 Injection in Patients With Wilson DiseaseRecruitingEarly Phase 1Ages 10-60Chaohui YuNo US site yet
- A Registered Cohort Study on Wilson's DiseaseRecruitingWan-Jin ChenNo US site yet
- Cardiac Involvement in Wilson's DiseaseRecruitingAges 18+Fondation Ophtalmologique Adolphe de RothschildNo US site yet
- Circadian Variation of Urinary Copper Excretion in Wilson Disease PatientsRecruitingAges 6-70Hospices Civils de LyonNo US site yet
- Description of Renal Involvement in Wilson's DiseaseRecruitingAges 7+Fondation Ophtalmologique Adolphe de RothschildNo US site yet
- Description of the Copper Concentration in Breast Milk in Women Treated for Wilson's DiseaseRecruitingAges 18+Fondation Ophtalmologique Adolphe de RothschildNo US site yet
- French Wilson Disease RegistryRecruitingAges 0-99Fondation Ophtalmologique Adolphe de RothschildNo US site yet
- Institutional Registry of Rare DiseasesRecruitingHospital Italiano de Buenos AiresNo US site yet
- International Wilson's Disease Patient Registry (iWilson Registry)RecruitingAges 12+OrphalanNo US site yet
- Oral Health and Wilson's Disease: SOMAWIRecruitingAges 18+Fondation Ophtalmologique Adolphe de RothschildNo US site yet
- Role for Biochemical Assays and Kayser-Fleischer Rings in Diagnosis of Wilson DiseaseRecruitingAges 6-65Second Affiliated Hospital, Zhejiang University, School of MedicineNo US site yet
- Spanish Wilson Disease RegistryRecruitingAges 18+Asociación Española para el Estudio del HígadoNo US site yet
- Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin ElasticityRecruitingAges 12+Centre Hospitalier Universitaire de Saint EtienneNo US site yet
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- Trial Alerts, when a new trial opens or a trial changes
- Disease Updates, FDA decisions and condition news, usually 1 or 2 emails a month
Who runs the Wilson Disease trials in the US, and what stage they are in
Of the 4 Wilson Disease trials with a US site, 1 is in Phase 3, the last stage before a company can ask the FDA for approval. One more is an earlier Phase 1 or 2 test of safety and dosing. The remaining 2 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 2 of them, and universities, hospitals, foundations and government groups run 2. Yale University runs the most, with 2. The most recently listed one first appeared on ClinicalTrials.gov on August 5, 2026.
Wilson Disease trials in the US, state by state
Of the 4 Wilson Disease trials with a US site, 3 accept children under 18. Their open sites are in 6 states, most often Connecticut, Texas and Colorado. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
US hospitals running the most Wilson Disease trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Wilson Disease.
- Advent HealthOrlando, Florida1 trial
- ARC Texas Liver InstituteSan Antonio, Texas1 trial
- Baylor College of MedicineHouston, Texas1 trial
- Northwestern University Division of Gastroenterology and HepatologyChicago, Illinois1 trial
- University of Colorado Anschutz School of MedicineDenver, Colorado1 trial
- University of Michigan Medical CentreAnn Arbor, Michigan1 trial
- Yale New Haven HospitalNew Haven, Connecticut1 trial
- Yale School of MedicineNew Haven, Connecticut1 trial
- Yale UniversityNew Haven, Connecticut1 trial
- Yale University School of MedicineNew Haven, Connecticut1 trial
Help getting to a Wilson Disease trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Wilson Disease trial near you
Are there Wilson Disease clinical trials near me?
As of November 13, 2026, 18 Wilson Disease clinical trials are recruiting now and 7 are not yet recruiting. In the US, 4 of them have at least 1 open site, across 6 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Wilson Disease clinical trial sites?
Recruiting Wilson Disease trials list open sites in Colorado, Connecticut, Florida, Illinois, Michigan and Texas.
Are there Wilson Disease trials for children near me?
Of the 4 Wilson Disease trials with a US site, 3 accept children under 18. Their open sites are in 6 states, most often Connecticut, Texas and Colorado. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Wilson Disease clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Wilson Disease trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Wilson Disease trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Wilson Disease: Cuprimine (penicillamine), Cuvrior (trientine tetrahydrochloride), Galzin (zinc acetate), Syprine (trientine hydrochloride).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.