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All 10 Primary Hyperoxaluria trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)Most sites in Alabama, Colorado and MissouriRecruitingPhase 2Ages 6+YolTech Therapeutics Co.4US sites
4 states - Rare Kidney Stone Consortium Patient RegistryMost sites in Minnesota and New YorkRecruitingAges 0-100Mayo Clinic3US sites
2 states - Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)Only in MinnesotaRecruitingPhase 1/2Ages 6-64Arbor Biotechnologies1US site
- Rare Kidney Stone Consortium BiobankOnly in MinnesotaRecruitingMayo Clinic1US site
- Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRDOnly in MinnesotaRecruitingPhase 2Dicerna Pharmaceuticals, Inc., a Novo Nordisk company1US site
- Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)RecruitingEarly Phase 1Ages 2+RenJi HospitalNo US site yet
- Evaluation of the Efficacy and Safety of Stiripentol in Patients 6 Years and Older With Primary Hyperoxaluria Type 1, 2 or 3RecruitingPhase 3Ages 6+BiocodexNo US site yet
- National Registry of Rare Kidney DiseasesRecruitingUK Kidney AssociationNo US site yet
- Phase I Exploratory Study of YOLT-203 in Patients With Primary Hyperoxaluria Type 1 (PH1)RecruitingPhase 1Ages 6+YolTech Therapeutics Co.No US site yet
- Retrospective and Prospective Follow-up of Patients With Primary Hyperoxaluria Type 1 Treated With Lumasiran in France.RecruitingAges 0-99Hospices Civils de LyonNo US site yet
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Who runs the Primary Hyperoxaluria trials in the US, and what stage they are in
None of the 5 Primary Hyperoxaluria trials with a US site is in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 3 of them. The remaining 2 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 3 of them, and universities, hospitals, foundations and government groups run 2. Mayo Clinic runs the most, with 2. The most recently listed one first appeared on ClinicalTrials.gov on May 14, 2026.
Primary Hyperoxaluria trials in the US, state by state
All 5 Primary Hyperoxaluria trials with a US site accept children under 18. Their open sites are in 6 states, most often Minnesota, Alabama and Colorado. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
US hospitals running the most Primary Hyperoxaluria trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Primary Hyperoxaluria.
- Mayo ClinicRochester, Minnesota2 trials
- Childrens Hospital of ColoradoAurora, Colorado1 trial
- Clinical Trial SiteRochester, Minnesota1 trial
- Cystinuria Registry - New York UniversityNew York, New York1 trial
- Dent Disease Registry -Mayo ClinicRochester, Minnesota1 trial
- Primary Hyperoxaluria Registry - Mayo ClinicRochester, Minnesota1 trial
- University of Alabama at Birmingham (UAB Hospital)Birmingham, Alabama1 trial
- University of Pennsylvania Health System (UPHS) - Penn MedicinePhiladelphia, Pennsylvania1 trial
- Washington University/Barnes Jewish HospitalSt Louis, Missouri1 trial
Help getting to a Primary Hyperoxaluria trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Primary Hyperoxaluria trial near you
Are there Primary Hyperoxaluria clinical trials near me?
As of November 13, 2026, 10 Primary Hyperoxaluria clinical trials are recruiting. In the US, 5 of them have at least 1 open site, across 6 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Primary Hyperoxaluria clinical trial sites?
Recruiting Primary Hyperoxaluria trials list open sites in Alabama, Colorado, Minnesota, Missouri, New York and Pennsylvania.
Are there Primary Hyperoxaluria trials for children near me?
All 5 Primary Hyperoxaluria trials with a US site accept children under 18. Their open sites are in 6 states, most often Minnesota, Alabama and Colorado. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Primary Hyperoxaluria clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Primary Hyperoxaluria trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Primary Hyperoxaluria trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Primary Hyperoxaluria: Rivfloza (nedosiran), Oxlumo (lumasiran).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.