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All 11 C3 Glomerulopathy trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGNMost sites in Colorado, Georgia and IowaRecruitingPhase 3Ages 12-100Novartis Pharmaceuticals5US sites
5 states - Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.Most sites in Iowa, Colorado and FloridaRecruitingPhase 3Ages 12-60Novartis Pharmaceuticals4US sites
3 states - A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3GMost sites in Florida, Georgia and South CarolinaRecruitingPhase 2Ages 16+Akebia Therapeutics3US sites
3 states - Pediatric Longitudinal Glomerular Disease: a PNRC Multi-Institutional Cohort StudyMost sites in Massachusetts and OhioRecruitingUp to age 18Pediatric Nephrology Research Consortium2US sites
2 states - Home Reported Outcomes in C3G StudyOnly in New JerseyRecruitingAges 18-100Novartis Pharmaceuticals1US site
- A Clinical Trial to Test the Safety, Tolerability, and How the Body Processes CPV-104 in Healthy People and Patients With C3-GlomerulopathyRecruitingPhase 1Ages 18+elevaNo US site yet
- A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 GlomerulopathyRecruitingAges 18-99Novartis PharmaceuticalsNo US site yet
- A Study to Assess the Efficacy and Safety of Pegcetacoplan for the Prevention of Recurrent C3G or Primary IC-MPGN in Kidney Transplant RecipientsRecruitingPhase 3Ages 12+Swedish Orphan BiovitrumNo US site yet
- Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 GlomerulopathyRecruitingPhase 2Ages 6+Region SkaneNo US site yet
- National Registry of Rare Kidney DiseasesRecruitingUK Kidney AssociationNo US site yet
- Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country StudyRecruitingPhase 4Swedish Orphan BiovitrumNo US site yet
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Who runs the C3 Glomerulopathy trials in the US, and what stage they are in
Of the 5 C3 Glomerulopathy trials with a US site, 2 are in Phase 3, the last stage before a company can ask the FDA for approval. One more is an earlier Phase 1 or 2 test of safety and dosing. The remaining 2 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 4 of them, and a university, hospital, foundation or government group runs the other. Novartis Pharmaceuticals runs the most, with 3. The most recently listed one first appeared on ClinicalTrials.gov on November 12, 2026.
C3 Glomerulopathy trials in the US, state by state
Of the 5 C3 Glomerulopathy trials with a US site, 4 accept children under 18. Their open sites are in 9 states, most often Colorado, Florida and Georgia. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
US hospitals running the most C3 Glomerulopathy trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know C3 Glomerulopathy.
- Childrens Hospital ColoradoAurora, Colorado2 trials
- University of Iowa Health CareIowa City, Iowa2 trials
- Boston Children's HospitalBoston, Massachusetts1 trial
- Cincinnati Children's Hospital Medical CenterCincinnati, Ohio1 trial
- Col Uni Med Center New York PresbyNew York, New York1 trial
- Georgia Nephrology Research InstLawrenceville, Georgia1 trial
- Nicklaus Childrens HospitalMiami, Florida1 trial
- University of MinnesotaMinneapolis, Minnesota1 trial
Help getting to a C3 Glomerulopathy trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a C3 Glomerulopathy trial near you
Are there C3 Glomerulopathy clinical trials near me?
As of November 13, 2026, 11 C3 Glomerulopathy clinical trials are recruiting now and 5 are not yet recruiting. In the US, 5 of them have at least 1 open site, across 10 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have C3 Glomerulopathy clinical trial sites?
Recruiting C3 Glomerulopathy trials list open sites in Colorado, Florida, Georgia, Iowa, Massachusetts, Minnesota, New Jersey, New York, Ohio and South Carolina.
Are there C3 Glomerulopathy trials for children near me?
Of the 5 C3 Glomerulopathy trials with a US site, 4 accept children under 18. Their open sites are in 9 states, most often Colorado, Florida and Georgia. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a C3 Glomerulopathy clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no C3 Glomerulopathy trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a C3 Glomerulopathy trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for C3 Glomerulopathy: Empaveli (pegcetacoplan), Fabhalta (iptacopan).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.