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All 34 Essential Thrombocythemia trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential ThrombocythemiaMost sites in California, Texas and New YorkRecruitingPhase 3Ages 18+Incyte45US sites
26 states - A Randomized Study of ASTX727 With or Without Iadademstat in Advanced Myeloproliferative Neoplasms (MPNs)Most sites in Florida, California and KansasRecruitingPhase 2Ages 18+National Cancer Institute (NCI)32US sites
13 states - Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and AnemiaMost sites in California, Florida and New YorkRecruitingPhase 1/2Ages 18+Disc Medicine29US sites
19 states - A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)Most sites in Florida, Texas and New YorkRecruitingPhase 3Ages 18+Novartis Pharmaceuticals23US sites
15 states - A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative NeoplasmsMost sites in Florida, California and TennesseeRecruitingPhase 1Ages 18+Prelude Therapeutics Incorporated11US sites
7 states - Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)Most sites in New York, Ohio and FloridaRecruitingPhase 2Ages 18+Icahn School of Medicine at Mount Sinai9US sites
5 states - Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent MyelofibrosisMost sites in Michigan, New York and TennesseeRecruitingPhase 2Ages 18+GlaxoSmithKline5US sites
5 states - A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)Most sites in Michigan, North Carolina and OhioRecruitingPhase 3Ages 18+Merck Sharp & Dohme4US sites
4 states - Ruxolitinib in Thrombocythemia and Polycythemia VeraOnly in MassachusettsRecruitingPhase 2Ages 18+Massachusetts General Hospital4US sites
- Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With CytopeniasMost sites in Kansas, New York and North CarolinaRecruitingPhase 2Ages 18+John Mascarenhas3US sites
3 states - Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative NeoplasmsOnly in CaliforniaRecruitingPhase 2Ages 18+University of Southern California2US sites
- MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)Most sites in Illinois and New YorkRecruitingAges 18+MPN Research Foundation2US sites
2 states - An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative NeoplasmsOnly in CaliforniaRecruitingPhase 1/2Ages 18+University of California, Irvine1US site
- Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative NeoplasmsOnly in WashingtonRecruitingPhase 2Ages 18+University of Washington1US site
- MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) TrialOnly in New YorkRecruitingPhase 2Ages 18+Icahn School of Medicine at Mount Sinai1US site
- Open Label Phase 1/2 Study of Tasquinimod in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (Post-PV MF), or Post-Essential Thrombocytosis Myelofibrosis (Post-ET MF)Only in TexasRecruitingPhase 1/2Ages 18+M.D. Anderson Cancer Center1US site
- Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 InhibitionOnly in PennsylvaniaRecruitingPhase 1Ages 18+Fox Chase Cancer Center1US site
- A Phase 2 Study to Assess STP938 (Dencatistat) as a Monotherapy in Adults With High Risk Essential Thrombocythaemia - The VECTRA TrialRecruitingPhase 2Ages 18+Step Pharma, SASNo US site yet
- A Post-Marketing Surveillance Study to Assess the Safety of Fedratinib in Korean Patients With MyelofibrosisRecruitingAges 19+Bristol-Myers SquibbNo US site yet
- A Study of GLB-001 in Patients With Myeloid MalignanciesRecruitingPhase 1Ages 18+Hangzhou GluBio Pharmaceutical Co.No US site yet
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Who runs the Essential Thrombocythemia trials in the US, and what stage they are in
Of the 18 Essential Thrombocythemia trials with a US site, 3 are in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 14 of them. The last one has no drug phase, such as a study that follows people over time or tests a device or a way of giving care. Companies run 6 of them, and universities, hospitals, foundations and government groups run 12. The sponsors with the most are Icahn School of Medicine at Mount Sinai (2) and John Mascarenhas (2). The most recently listed one first appeared on ClinicalTrials.gov on July 29, 2026.
Essential Thrombocythemia trials in the US, state by state
None of the 18 Essential Thrombocythemia trials with a US site lists children under 18 as eligible. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 24 states
US hospitals running the most Essential Thrombocythemia trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Essential Thrombocythemia.
- Memorial Sloan Kettering Cancer CenterNew York, New York4 trials
- Moffitt Cancer CenterTampa, Florida4 trials
- Oregon Health and Science UniversityPortland, Oregon3 trials
- Icahn School of Medicine at Mount SinaiNew York, New York2 trials
- Massachusetts General HospitalBoston, Massachusetts2 trials
- MD Anderson Cancer CenterHouston, Texas2 trials
- Ruttenberg Treatment CenterNew York, New York2 trials
- The Ohio State UniversityColumbus, Ohio2 trials
- Wake Forest Baptist Health Comprehensive Cancer CenterWinston-Salem, North Carolina2 trials
- American Oncology Partners PA Center for Cancer and Blood DisordersBethesda, Maryland1 trial
Help getting to an Essential Thrombocythemia trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Corporate Angel Network
- Puts cancer patients in empty seats on business jets for treatment, second opinions and clinical trials. Open to anyone with cancer who can walk and travel without medical help, and it does not check income.
- American Cancer Society Hope Lodge
- Offers a free place to stay at 31 Hope Lodge locations for people getting cancer treatment far from home. People facing cancer and their caregivers, when treatment is far from home.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding an Essential Thrombocythemia trial near you
Are there Essential Thrombocythemia clinical trials near me?
As of November 13, 2026, 34 Essential Thrombocythemia clinical trials are recruiting now and 4 are not yet recruiting. In the US, 18 of them have at least 1 open site, across 33 states and Washington, DC. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Essential Thrombocythemia clinical trial sites?
Recruiting Essential Thrombocythemia trials list open sites in 33 states and Washington, DC. New York, California and Florida have the most, and the table on this page lists every state.
Are there Essential Thrombocythemia trials for children near me?
None of the 18 Essential Thrombocythemia trials with a US site lists children under 18 as eligible. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to an Essential Thrombocythemia clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights, and Corporate Angel Network flies cancer patients for free.
What if there is no Essential Thrombocythemia trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when an Essential Thrombocythemia trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Essential Thrombocythemia: Besremi (ropeginterferon alfa-2b-njft), Agrylin (anagrelide hydrochloride).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.