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All 25 Hemophilia B trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic DisordersMost sites in California, Ohio and FloridaRecruitingAmerican Thrombosis and Hemostasis Network76US sites
31 states - A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia BMost sites in California, Texas and ArizonaRecruitingPhase 1/2Ages 2+Regeneron Pharmaceuticals17US sites
12 states - SEVENFACT® for Bleeding Events in Hemophilia With InhibitorsMost sites in Michigan, California and GeorgiaRecruitingPhase 4Ages 12-100American Thrombosis and Hemostasis Network17US sites
13 states - Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B RespectivelyMost sites in California, Florida and New YorkRecruitingPhase 3Ages 18+Pfizer14US sites
6 states - A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)Most sites in Pennsylvania, California and IllinoisRecruitingPhase 1Ages 18-60Equilibra Bioscience8US sites
7 states - Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia BMost sites in California, Florida and GeorgiaRecruitingPhase 3Ages 138 Months-206 MonthsCSL Behring6US sites
5 states - Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)Most sites in California, Michigan and PennsylvaniaRecruitingPhase 3Ages 18+CSL Behring4US sites
4 states - Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without InhibitorsMost sites in New York, Pennsylvania and WashingtonRecruitingPhase 3Ages 1-74Pfizer3US sites
3 states - A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia BOnly in UtahRecruitingPhase 3Ages 1-17Pfizer1US site
- An Observational Cohort Study to Characterize the Effectiveness and Safety of HEMGENIX® in Patients With Hemophilia BOnly in New YorkRecruitingAges 18+CSL Behring1US site
- ATHNdataset RegistryOnly in North CarolinaRecruitingAmerican Thrombosis and Hemostasis Network1US site
- A Study to Evaluate the Safety and Efficacy of ZS801 in Adult Hemophilia B PatientsRecruitingPhase 1/2Ages 18+Institute of Hematology & Blood Diseases Hospital, ChinaNo US site yet
- An Open-Label, Comparative Study of the Efficacy, Safety and Pharmacodynamics of Single Dose of ANB-002 in Patients With Hemophilia BRecruitingPhase 3Ages 18+BiocadNo US site yet
- An Open-label, Multicenter Phase I/II Clinical Trial to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic/Pharmacodynamic (PK/PD) Characteristics of SR604 Injection in Patients With Hemophilia A/B and Congenital Factor VII DeficiencyRecruitingPhase 1/2Ages 18-65Shanghai RAAS Blood Products Co.No US site yet
- Development of Non-Invasive Prenatal Diagnosis for Single Gene DisordersRecruitingAges 18+Assistance Publique - Hôpitaux de ParisNo US site yet
- Gene Therapy for Hemophilia B Patients Aged 12-18 Years OldRecruitingPhase 1Ages 12-18Institute of Hematology & Blood Diseases Hospital, ChinaNo US site yet
- German Pediatric Hemophilia Research DatabaseRecruitingUp to age 18Goethe UniversityNo US site yet
- Liver Biopsy In Haemophilia Gene TherapyRecruitingAges 18-80University College, LondonNo US site yet
- Longitudinal Cohort of Thrombosis and Hemostasis DiseasesRecruitingPeking University People's HospitalNo US site yet
- National Longitudinal Cohort of Hematological DiseasesRecruitingInstitute of Hematology & Blood Diseases Hospital, ChinaNo US site yet
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Who runs the Hemophilia B trials in the US, and what stage they are in
Of the 12 Hemophilia B trials with a US site, 5 are in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 2 of them. One is a Phase 4 study of an already approved treatment. The remaining 4 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 8 of them, and universities, hospitals, foundations and government groups run 4. The sponsors with the most are American Thrombosis and Hemostasis Network (3), CSL Behring (3) and Pfizer (3). The most recently listed one first appeared on ClinicalTrials.gov on July 23, 2025.
Hemophilia B trials in the US, state by state
Of the 12 Hemophilia B trials with a US site, 7 accept children under 18. Their open sites are in 33 states and Washington, DC, most often California, Michigan and Tennessee. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 24 states
US hospitals running the most Hemophilia B trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Hemophilia B.
- St. Jude Children's Research HospitalMemphis, Tennessee3 trials
- Vanderbilt University Medical CenterNashville, Tennessee3 trials
- American Thrombosis and Hemostasis NetworkRochester, New York2 trials
- Arkansas Center for Bleeding DisordersLittle Rock, Arkansas2 trials
- Brody School of Medicine at East Carolina UniversityGreenville, North Carolina2 trials
- Children's Hospital Los AngelesLos Angeles, California2 trials
- Indiana Hemophilia and Thrombosis CenterIndianapolis, Indiana2 trials
- Massachusetts General Hospital Comprehensive Hemophilia and Thrombosis Treatment CenterBoston, Massachusetts2 trials
- Rady Children's Hospital San DiegoSan Diego, California2 trials
- Rush University Medical CenterChicago, Illinois2 trials
Help getting to a Hemophilia B trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Hemophilia B trial near you
Are there Hemophilia B clinical trials near me?
As of November 13, 2026, 25 Hemophilia B clinical trials are recruiting now and 5 are not yet recruiting. In the US, 12 of them have at least 1 open site, across 33 states and Washington, DC. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Hemophilia B clinical trial sites?
Recruiting Hemophilia B trials list open sites in 33 states and Washington, DC. California, Michigan and Pennsylvania have the most, and the table on this page lists every state.
Are there Hemophilia B trials for children near me?
Of the 12 Hemophilia B trials with a US site, 7 accept children under 18. Their open sites are in 33 states and Washington, DC, most often California, Michigan and Tennessee. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Hemophilia B clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Hemophilia B trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Hemophilia B trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Hemophilia B: Alhemo (concizumab), Hemgenix (etranacogene dezaparvovec), Hympavzi (marstacimab), Qfitlia (fitusiran), Alprolix (coagulation factor ix (recombinant), fc fusion protein (eftrenonacog alfa)), BeneFIX (coagulation factor ix (recombinant)), Feiba (anti-inhibitor coagulant complex), Idelvion (coagulation factor ix (recombinant), albumin fusion protein (albutrepenonacog alfa)) and 3 more on the disease page.
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.
