Arcturus Therapeutics Holdings Inc

Arcturus Therapeutics Holdings Inc works on 2 rare diseases tracked on Trial Friend, including Cystic Fibrosis, Urea Cycle Disorders, with 2 recruiting clinical trials.

Arcturus Therapeutics is a commercial mRNA medicines and vaccines company developing therapies for liver and respiratory rare diseases. The company's platform technologies include STARR, a self-amplifying mRNA technology, and LUNAR, a lipid-mediated delivery system for therapeutic RNA and DNA to target cells.

Type
Rare Disease Specialist
Ticker
ARCT
Headquarters
San Diego, United States
Founded
2013
2
Active Rare Disease Trials
2
Rare Diseases in Portfolio
13
Years Active

Focus areas at Arcturus Therapeutics Holdings Inc

As a rare disease specialist, Arcturus Therapeutics Holdings Inc has active clinical trial programs and drug development efforts across 2 rare diseases, including Cystic Fibrosis, Urea Cycle Disorders. These programs may span orphan drug designation, novel therapeutic mechanisms, and precision medicine approaches targeting the underlying causes of each disease.

The clinical trials section below shows all active and recruiting studies sponsored by Arcturus Therapeutics Holdings Inc, sourced live from ClinicalTrials.gov. Each trial includes its current recruitment status, study phase (Phase 1 through Phase 4), conditions under investigation, and the number of active trial sites. The FDA-approved drugs section lists treatments that have received U.S. Food and Drug Administration approval, with brand names, generic names, approval dates, and matched rare disease indications from the openFDA database.

Arcturus Therapeutics Holdings Inc is headquartered in San Diego, United States, founded in 2013, publicly traded under the ticker symbol ARCT. The company dedicates its research and development resources exclusively to rare and orphan diseases, working to bring innovative treatments to patients with conditions that have historically had limited or no treatment options.

Arcturus Therapeutics Holdings Inc Drug Pipeline

Arcturus Therapeutics Holdings Inc has 2 active clinical trials across 1 development stage, with 2 currently recruiting participants. Clinical trials advance through phases: Phase 1 tests safety in a small group, Phase 2 evaluates effectiveness and side effects, Phase 3 confirms benefit in a larger population, and Phase 4 monitors long-term safety after FDA approval.

Note: This pipeline includes all of Arcturus Therapeutics Holdings Inc's active interventional trials, not only those targeting rare diseases. We show the full pipeline because a company's broader research activity, therapeutic expertise, and development infrastructure directly shape its ability to advance rare disease programs. A strong overall pipeline often signals deeper clinical operations, faster enrollment capabilities, and greater commitment to bringing new treatments to patients.

Understand Arcturus Therapeutics Holdings Inc's pipeline
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2
Phase 22 trials
Recruiting
Recruiting

Arcturus Therapeutics Holdings Inc Clinical Trials (2)

Active and recruiting clinical trials sponsored by Arcturus Therapeutics Holdings Inc, sourced live from ClinicalTrials.gov. Each trial card shows the study phase, current recruitment status, conditions under investigation, study locations, eligibility criteria, and a direct link to the full ClinicalTrials.gov record. You can also download a one-page PDF summary to share with your doctor.

Note: Recruitment statuses on ClinicalTrials.gov may not immediately reflect recent FDA decisions, sponsor announcements, or enrollment changes. Always confirm a trial's current status directly with the study coordinator.

Ask about Arcturus Therapeutics Holdings Inc's trials
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RECRUITINGPHASE2Updated a few months agoNCT06747858

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

Intervention: ARCT-032

Cystic FibrosisCFTR Gene Mutation

ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy or are not taking CFTR modulators due to drug intolerance, poor response, or lack of access to modulators.

Ages 18 Years+13 locations
View full study
RECRUITINGPHASE2Hasn't posted an update in over a yearNCT06488313

A Study to Evaluate the Pharmacodynamics and Safety of ARCT-810 in Participants With OTCD

Intervention: ARCT-810

OTC DeficiencyOrnithine Transcarbamylase DeficiencyOTCD

Evaluate the safety and pharmacodynamics of multiple doses of ARCT-810 in adolescent and adult participants with OTC deficiency.

Ages 12 Years+1 location
View full study

FDA-Approved Drugs

No FDA-approved drugs found for this company at this time.

Arcturus Therapeutics Holdings Inc Trial Locations

Arcturus Therapeutics Holdings Inc clinical trials are running at 14 sites in 1 country. Click any country to drill down by state, city, and individual research facility. Proximity to a trial site is one of the most important factors in deciding whether to participate.

United States
14▼

Rare Disease Focus Areas (2)

Diseases targeted by Arcturus Therapeutics Holdings Inc's clinical trial and drug development programs

Patient Resources

Organizations and resources related to Arcturus Therapeutics Holdings Inc's rare disease focus areas

Frequently Asked Questions About Arcturus Therapeutics Holdings Inc

Common questions about Arcturus Therapeutics Holdings Inc's rare disease programs, clinical trials, and treatments.