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Hypophosphatasia Clinical Trials Near Me

As of October 19, 2026, 7 Hypophosphatasia clinical trials are recruiting. 3 of them have at least 1 open site in the United States, across 13 states. Enter your ZIP code to see which are closest to you.

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All 7 Hypophosphatasia trials and their US sites

Enter your ZIP code above to sort them by how far their nearest open site is from you.

  1. A Prospective Sub-Study of the Global Hypophosphatasia Registry
    Clinical Trial Site, Hartford, Connecticut; Clinical Trial Site, Chicago, Illinois; Clinical Trial Site, Boston, Massachusetts and 9 more sites
    RecruitingRun by Alexion Pharmaceuticals, Inc.
  2. Natural History Study of Patients With Hypophosphatasia (HPP)
    Duke University Medical Center, Durham, North Carolina
    RecruitingRun by Duke University
  3. Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
    Sanford Health, Sioux Falls, South Dakota
    RecruitingRun by Sanford Health
  4. A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults With Hypophosphatasia in Order to Identify Suitable Doses of ALE1
    No open US site listed yet
    RecruitingPhase 1/2Ages 18 to 50Run by Alesta Therapeutics
  5. Characteristics of Hypophosphatasia in Adult Patients in Rheumatology and Their Value in Developing an Algorithm to HPP-diagnosis - the COHIR Multi-center Study
    No open US site listed yet
    RecruitingAges 18+Run by University of Bonn
  6. Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)
    No open US site listed yet
    RecruitingAges 18+Run by Assistance Publique - Hôpitaux de Paris
  7. The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia
    No open US site listed yet
    RecruitingRun by AstraZeneca
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Where Hypophosphatasia trials are recruiting in the US

The US cities with the most Hypophosphatasia trials recruiting are Boston, Massachusetts (1), Charlottesville, Virginia (1), Chicago, Illinois (1), Cincinnati, Ohio (1) and Columbus, Ohio (1), counting trials with at least 1 open site in each city.

Hospitals that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Hypophosphatasia, even if no trial fits you.

Boston, Massachusetts
1 trial recruiting
  • Clinical Trial Site
Charlottesville, Virginia
1 trial recruiting
  • Clinical Trial Site
Chicago, Illinois
1 trial recruiting
  • Clinical Trial Site
Cincinnati, Ohio
1 trial recruiting
  • Clinical Trial Site
Columbus, Ohio
1 trial recruiting
  • Clinical Trial Site
Durham, North Carolina
1 trial recruiting
  • Duke University Medical Center
Hartford, Connecticut
1 trial recruiting
  • Clinical Trial Site
Kansas City, Missouri
1 trial recruiting
  • Clinical Trial Site

States with at least 1 open site: Connecticut, Illinois, Massachusetts, Missouri, New York, North Carolina, Ohio, Pennsylvania, South Dakota, Tennessee, Utah, Virginia, Wisconsin.

Questions about finding a Hypophosphatasia trial near you

Are there Hypophosphatasia clinical trials near me?

As of October 19, 2026, 7 Hypophosphatasia clinical trials are recruiting. 3 of them have at least 1 open site in the United States, across 13 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.

Which states have Hypophosphatasia clinical trial sites?

As of October 19, 2026, recruiting Hypophosphatasia trials list open sites in Connecticut, Illinois, Massachusetts, Missouri, New York, North Carolina, Ohio, Pennsylvania, South Dakota, Tennessee, Utah, Virginia and Wisconsin.

What if there is no Hypophosphatasia trial near me?

Some trials pay for or reimburse travel and lodging, and a few send staff or use local labs so fewer visits happen at the study site, so ask the study contact before ruling a trial out. You can also sign up on this page to get an email when a Hypophosphatasia trial opens a new site or changes status.

How is the distance to a trial site measured?

Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.

FDA-approved for Hypophosphatasia: Strensiq (asfotase alfa).

Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of October 19, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out.