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All 41 Neuromyelitis Optica trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSDMost sites in California, Florida and IllinoisRecruitingAges 18+Ad scientiam10US sites
9 states - Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor TherapiesMost sites in District of Columbia, Massachusetts and North CarolinaRecruitingAges 18+Alexion Pharmaceuticals6US sites
6 states - Study of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum DisorderMost sites in California, Massachusetts and TexasRecruitingPhase 2Ages 2-17Amgen4US sites
3 states - A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)Only in ColoradoRecruitingPhase 3Ages 2-11Hoffmann-La Roche1US site
- Biorepository and Registry for Plasma Exchange PatientsOnly in IowaRecruitingAges 12-99Charles M Knudson1US site
- Impact of a Structured Wellness Behavioral Intervention on Quality of Life in NMOSDOnly in New YorkRecruitingAges 18+Icahn School of Medicine at Mount Sinai1US site
- Longitudinal Cortical Demyelination in Multiple Sclerosis and Related DisordersOnly in New YorkRecruitingAges 18+Icahn School of Medicine at Mount Sinai1US site
- MS-ResearchBiomarkerSOnly in CaliforniaRecruitingAges 18+Cedars-Sinai Medical Center1US site
- Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During PregnancyOnly in ColoradoRecruitingAges 15+Amgen1US site
- Study of the Clinical and Radiological Impact of Ravulizumab in People With Neuromyelitis Optica Spectrum DisorderOnly in TexasRecruitingAges 18+University of Texas Southwestern Medical Center1US site
- Study of Ultomiris® (Ravulizumab) Safety in PregnancyOnly in MassachusettsRecruitingAlexion Pharmaceuticals1US site
- A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD)RecruitingPhase 2/3Ages 18+Shanghai Jiaolian Drug Research and Development Co.No US site yet
- A Multicenter Prospective Real-World Effectiveness and Safety of Satralizumab in the Early Treatment of Attacks in NMOSDRecruitingAges 18+Junwei Hao, MDNo US site yet
- A Study of C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard TherapyRecruitingPhase 1Ages 18-70RenJi HospitalNo US site yet
- A Study to Evaluate the Efficacy and Safety of JYP0061 in Patients With Acute Neuromyelitis Spectrum Disease (NMOSD)RecruitingPhase 2Ages 18-65Guangzhou JOYO Pharma Co.No US site yet
- Biomarkers in Autoimmune Disease of Nervous SystemRecruitingAges 18+Tongji HospitalNo US site yet
- Clinical and Imaging Cohort of Neuroinflammation Diseases in China (CLUE)RecruitingAges 16-75Beijing Tiantan HospitalNo US site yet
- Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study.RecruitingAges 18+icometrixNo US site yet
- Clinical Study of B001 Injection in Subjects With Neuromyelitis Optic Spectrum Disorder (NMOSD)RecruitingEarly Phase 1Ages 18+Shanghai Pharmaceuticals Holding Co.No US site yet
- Cohort Study on Neuroimmune Diseases in the Reproductive AgeRecruitingAges 20-55Third Affiliated Hospital, Sun Yat-Sen UniversityNo US site yet
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Who runs the Neuromyelitis Optica trials in the US, and what stage they are in
Of the 11 Neuromyelitis Optica trials with a US site, 1 is in Phase 3, the last stage before a company can ask the FDA for approval. One more is an earlier Phase 1 or 2 test of safety and dosing. The remaining 9 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 5 of them, and universities, hospitals, foundations and government groups run 6. The sponsors with the most are Alexion Pharmaceuticals (2), Amgen (2) and Icahn School of Medicine at Mount Sinai (2). The most recently listed one first appeared on ClinicalTrials.gov on January 17, 2025.
Neuromyelitis Optica trials in the US, state by state
Of the 11 Neuromyelitis Optica trials with a US site, 5 accept children under 18. Their open sites are in 5 states, most often Colorado, Massachusetts and California. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 6 states
US hospitals running the most Neuromyelitis Optica trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Neuromyelitis Optica.
- CC Lou Ruvo Center for Brain HealthLas Vegas, Nevada1 trial
- Cedars-Sinai Medical CenterLos Angeles, California1 trial
- Children's Hospital Colorado.Denver, Colorado1 trial
- Clinical Trial SiteWashington D.C., District of Columbia1 trial
- Clinical Trial SiteChapel Hill, North Carolina1 trial
- Clinical Trial SiteColumbus, Ohio1 trial
- Clinical Trial SitePlano, Texas1 trial
- Clinical Trial SiteMilwaukee, Wisconsin1 trial
- Corinne Goldsmith Dickinson Center for MS at Mount SinaiNew York, New York1 trial
- DeGowin blood CenterIowa City, Iowa1 trial
Help getting to a Neuromyelitis Optica trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Neuromyelitis Optica trial near you
Are there Neuromyelitis Optica clinical trials near me?
As of November 13, 2026, 41 Neuromyelitis Optica clinical trials are recruiting now and 20 are not yet recruiting. In the US, 11 of them have at least 1 open site, across 15 states and Washington, DC. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Neuromyelitis Optica clinical trial sites?
Recruiting Neuromyelitis Optica trials list open sites in 15 states and Washington, DC. Massachusetts, California and Texas have the most, and the table on this page lists every state.
Are there Neuromyelitis Optica trials for children near me?
Of the 11 Neuromyelitis Optica trials with a US site, 5 accept children under 18. Their open sites are in 5 states, most often Colorado, Massachusetts and California. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Neuromyelitis Optica clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights.
What if there is no Neuromyelitis Optica trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Neuromyelitis Optica trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Neuromyelitis Optica: Enspryng (satralizumab), Soliris (eculizumab), Ultomiris (ravulizumab-cwvz), Uplizna (inebilizumab-cdon).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.