Hereditary Spastic Paraplegia Clinical Trials Near Me
As of October 12, 2026, 19 Hereditary Spastic Paraplegia clinical trials are recruiting or about to open (18 recruiting now, 1 opening soon). 9 of them have at least 1 open site in the United States, across 11 states. Enter your ZIP code to see which are closest to you.
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All 18 Hereditary Spastic Paraplegia trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- Spastic Paraplegia - Centers of Excellence Research NetworkUniversity of Miami Miller School of Medicine, Miami, Florida; University of Iowa Carver College of Medicine, Iowa City, Iowa; Boston Children's Hospital, Boston, Massachusetts and 8 more sitesRecruitingRun by Boston Children's Hospital
- Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular DiseaseNextGen Precision Health Building, Clinical and Translational Science Unit, Columbia, MissouriRecruitingAges 18+Run by University of Missouri-Columbia
- Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)Boston Children's Hospital, Boston, MassachusettsRecruitingAges 1 Month to 30Run by Boston Children's Hospital
- Melpida: Recombinant Adeno-associated Virus (Serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)Children's Medical Center Dallas, Dallas, TexasRecruitingPhase 1/2Ages 4 Months to 10Run by Elpida Therapeutics SPC
- Natural History Study of Patients with HPDL MutationsEun Hae Lee, San Diego, CaliforniaRecruitingRun by University of California, San Diego
- Neuromodulation to Enhance Motor Function in HSPUniversity of Kentucky, Lexington, KentuckyRecruitingAges 18+Run by Rahul Sachdeva
- Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.University of Texas Southwestern Medical Center, Dallas, TexasRecruitingPhase 3Ages 4 Months to 72 MonthsRun by Elpida Therapeutics SPC
- Registry and Natural History Study for Early Onset Hereditary Spastic ParaplegiaBoston Children's Hospital, Boston, MassachusettsRecruitingUp to age 30Run by Boston Children's Hospital
- A Prospective Cohort Study of ITB Treatment for HSPNo open US site listed yetRecruitingAges 14 to 70Run by Shanghai 6th People's Hospital
- A Prospective Cohort Study of Surgical Treatment for Foot Deformities in HSPNo open US site listed yetRecruitingAges 10 to 45Run by Shanghai 6th People's Hospital
- Calcium Folinate Treatment of Spastic Paraplegia 56No open US site listed yetRecruitingEarly Phase 1Run by Shanghai 6th People's Hospital
- Flexibility, Resistance, Aerobic, Movement Execution Training in Adults With Hereditary Spastic ParaplegiaNo open US site listed yetRecruitingAges 18+Run by IRCCS Eugenio Medea
- Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic PathologyNo open US site listed yetRecruitingAges 18+Run by Centre Hospitalier Universitaire de Liege
- Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related DisordersNo open US site listed yetRecruitingRun by Dr. Rebecca Schule
- Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP)No open US site listed yetRecruitingAges 4 to 70Run by IRCCS Eugenio Medea
- STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic StrategiesNo open US site listed yetRecruitingRun by IRCCS Fondazione Stella Maris
- The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4No open US site listed yetRecruitingAges 18 to 70Run by University Hospital Tuebingen
- TreatHSP Platform: Adaptive Natural History Platform for Ataxias, HSPs, and Spastic AtaxiasNo open US site listed yetRecruitingAges 5+Run by Heidelberg University
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Where Hereditary Spastic Paraplegia trials are recruiting in the US
The US cities with the most Hereditary Spastic Paraplegia trials recruiting are Boston, Massachusetts (4), Dallas, Texas (3), Ann Arbor, Michigan (1), Cincinnati, Ohio (1) and Columbia, Missouri (1), counting trials with at least 1 open site in each city.
Hospitals that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Hereditary Spastic Paraplegia, even if no trial fits you.
- Boston Children's Hospital
- Massachusetts General Hospital
- Children's Medical Center Dallas
- Scottish Rite for Children
- University of Texas Southwestern Medical Center
- University of Michigan School of Medicine
- Cincinnati Children's Hospital Medical Center
- NextGen Precision Health Building, Clinical and Translational Science Unit
- Texas Children's Hospital
- University of Iowa Carver College of Medicine
- University of Kentucky
States with at least 1 open site: California, Florida, Iowa, Kentucky, Massachusetts, Michigan, Missouri, New York, Ohio, Texas, Washington.
Questions about finding a Hereditary Spastic Paraplegia trial near you
Are there Hereditary Spastic Paraplegia clinical trials near me?
As of October 12, 2026, 19 Hereditary Spastic Paraplegia clinical trials are recruiting or about to open (18 recruiting now, 1 opening soon). 9 of them have at least 1 open site in the United States, across 11 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Hereditary Spastic Paraplegia clinical trial sites?
As of October 12, 2026, recruiting Hereditary Spastic Paraplegia trials list open sites in California, Florida, Iowa, Kentucky, Massachusetts, Michigan, Missouri, New York, Ohio, Texas and Washington.
What if there is no Hereditary Spastic Paraplegia trial near me?
Some trials pay for or reimburse travel and lodging, and a few send staff or use local labs so fewer visits happen at the study site, so ask the study contact before ruling a trial out. You can also sign up on this page to get an email when a Hereditary Spastic Paraplegia trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of October 12, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out.