Also on Trial Friend:Cholangiocarcinoma pageMatch Me
All 186 Cholangiocarcinoma trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryMost sites in California, New York and MarylandRecruitingMassive Bio67US sites
40 states - Integrated Cancer Repository for Cancer ResearchMost sites in Missouri, Nebraska and FloridaRecruitingAges 19-110University of Nebraska42US sites
18 states - A Study of PHST001 in Advanced Solid TumorsMost sites in Texas, California and MichiganRecruitingPhase 1Ages 18+Pheast Therapeutics20US sites
11 states - A Study of LY4337713 in Participants With FAP-Positive Solid TumorsMost sites in California, Massachusetts and MichiganRecruitingPhase 1Ages 18+Eli Lilly and Company19US sites
13 states - A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid TumorsMost sites in Texas, Arizona and CaliforniaRecruitingPhase 1/2Ages 18+Alentis Therapeutics9US sites
8 states - Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated CholangiocarcinomaMost sites in California, Florida and IllinoisRecruitingPhase 1/2Ages 18+Genfit8US sites
6 states - A Study of MGC028 in Participants With Advanced Solid TumorsMost sites in Massachusetts, California and MichiganRecruitingPhase 1Ages 18+MacroGenics7US sites
6 states - Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With SurgeryMost sites in New York and New JerseyRecruitingPhase 2Ages 18+Memorial Sloan Kettering Cancer Center7US sites
2 states - Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid TumorsMost sites in Texas, Colorado and FloridaRecruitingPhase 1/2Ages 18+ModeX Therapeutics, An OPKO Health Company6US sites
5 states - The Dragon PLC Trial (DRAGON-PLC)Most sites in Connecticut, Illinois and MinnesotaRecruitingAges 18+Maastricht University5US sites
5 states - SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or MesotheliomaMost sites in Florida, Pennsylvania and TexasRecruitingPhase 1Ages 18+Verismo Therapeutics4US sites
4 states - A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or RearrangementMost sites in Alabama, New York and OhioRecruitingPhase 2Ages 18+Mehmet Akce3US sites
3 states - At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced CancerMost sites in Florida and North DakotaRecruitingPhase 2Ages 18+Mayo Clinic2US sites
2 states - Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract CancerOnly in MarylandRecruitingPhase 1Ages 21+University of Maryland, Baltimore2US sites
- Liver Transplantation in Intrahepatic CholangiocarcinomaOnly in New JerseyRecruitingAges 18-89Rutgers, The State University of New Jersey2US sites
- Olutasidenib DDI Study in Patients With IDH1 Mutation Positive MalignanciesMost sites in California and New YorkRecruitingPhase 4Ages 18+Rigel Pharmaceuticals2US sites
2 states - [18F]FTT Positron Emission Tomography/Computed Tomography to Predict Treatment Response in Patients Scheduled to Receive Gemcitabine, Cisplatin, and Durvalumab for Newly Diagnosed CholangiocarcinomaOnly in WashingtonRecruitingPhase 2Ages 18+University of Washington1US site
- 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer DetectionOnly in MarylandRecruitingPhase 2Ages 18-120National Cancer Institute (NCI)1US site
- A Noninvasive and Screening miRNA Signature for Gastrointestinal CancerOnly in CaliforniaRecruitingAges 18+City of Hope Medical Center1US site
- A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic CholangiocarcinomaOnly in TexasRecruitingPhase 2Ages 18+M.D. Anderson Cancer Center1US site
New trials, status changes and new sites, straight from ClinicalTrials.gov. Unsubscribe anytime.
- Trial Alerts, when a new trial opens or a trial changes
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Who runs the Cholangiocarcinoma trials in the US, and what stage they are in
None of the 64 Cholangiocarcinoma trials with a US site is in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 40 of them. One is a Phase 4 study of an already approved treatment. The remaining 23 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 11 of them, and universities, hospitals, foundations and government groups run 53. The sponsors with the most are National Cancer Institute (NCI) (6), M.D. Anderson Cancer Center (5) and Mayo Clinic (5). The most recently listed one first appeared on ClinicalTrials.gov on October 14, 2026.
Cholangiocarcinoma trials in the US, state by state
Of the 64 Cholangiocarcinoma trials with a US site, 4 accept children under 18. Their open sites are in 40 states, most often Maryland, Ohio and Texas. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 33 states
US hospitals running the most Cholangiocarcinoma trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Cholangiocarcinoma.
- MD Anderson Cancer CenterHouston, Texas6 trials
- National Institutes of Health Clinical CenterBethesda, Maryland6 trials
- M D Anderson Cancer CenterHouston, Texas3 trials
- Massachusetts General HospitalBoston, Massachusetts3 trials
- University of PennsylvaniaPhiladelphia, Pennsylvania3 trials
- USC Norris Comprehensive Cancer CenterLos Angeles, California3 trials
- Beth Israel Deaconess Medical CenterBoston, Massachusetts2 trials
- City of Hope Medical CenterDuarte, California2 trials
- Mayo ClinicRochester, Minnesota2 trials
- Mayo Clinic in FloridaJacksonville, Florida2 trials
Help getting to a Cholangiocarcinoma trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Corporate Angel Network
- Puts cancer patients in empty seats on business jets for treatment, second opinions and clinical trials. Open to anyone with cancer who can walk and travel without medical help, and it does not check income.
- American Cancer Society Hope Lodge
- Offers a free place to stay at 31 Hope Lodge locations for people getting cancer treatment far from home. People facing cancer and their caregivers, when treatment is far from home.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Cholangiocarcinoma trial near you
Are there Cholangiocarcinoma clinical trials near me?
As of November 13, 2026, 186 Cholangiocarcinoma clinical trials are recruiting now and 58 are not yet recruiting. In the US, 64 of them have at least 1 open site, across 43 states. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Cholangiocarcinoma clinical trial sites?
Recruiting Cholangiocarcinoma trials list open sites in 43 states. California, Texas and Maryland have the most, and the table on this page lists every state.
Are there Cholangiocarcinoma trials for children near me?
Of the 64 Cholangiocarcinoma trials with a US site, 4 accept children under 18. Their open sites are in 40 states, most often Maryland, Ohio and Texas. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Cholangiocarcinoma clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights, and Corporate Angel Network flies cancer patients for free.
What if there is no Cholangiocarcinoma trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Cholangiocarcinoma trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Cholangiocarcinoma: Imfinzi (durvalumab), Keytruda (pembrolizumab), Lyrfigtu (lirafugratinib), Lytgobi (futibatinib), Pemazyre (pemigatinib), Tibsovo (ivosidenib), Ziihera (zanidatamab), Bizengri (zenocutuzumab-zbco).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.