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All 31 Diffuse Intrinsic Pontine Glioma trials and their US sites
Enter your ZIP code above to sort them by how far their nearest open site is from you.
- CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and LymphomaMost sites in New York, California and TexasRecruitingPhase 1/2Ages 12 Months-21Children's Oncology Group33US sites
23 states - Combination Therapy for the Treatment of Diffuse Midline GliomasMost sites in California, Alabama and District of ColumbiaRecruitingPhase 2Ages 2-39University of California, San Francisco19US sites
17 states - Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and SarcomasMost sites in Florida, Alabama and ArkansasRecruitingPhase 1/2Up to age 26Milton S. Hershey Medical Center14US sites
11 states - PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent MedulloblastomaMost sites in Ohio, Colorado and District of ColumbiaRecruitingPhase 2Ages 3-39Nationwide Children's Hospital13US sites
12 states - Targeted Pediatric High-Grade Glioma TherapyMost sites in Ohio, Colorado and District of ColumbiaRecruitingAges 12 Months-39Nationwide Children's Hospital12US sites
11 states - ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade GliomasMost sites in Ohio, Colorado and District of ColumbiaRecruitingPhase 2Ages 12 Months-39Nationwide Children's Hospital11US sites
10 states - Study of Olutasidenib and Temozolomide in HGGMost sites in Ohio, Colorado and District of ColumbiaRecruitingPhase 2Ages 12-39Rigel Pharmaceuticals11US sites
10 states - Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantMost sites in Ohio, Colorado and District of ColumbiaRecruitingPhase 2Ages 12 Months-39Nationwide Children's Hospital11US sites
10 states - Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK FusionMost sites in Ohio, Colorado and District of ColumbiaRecruitingEarly Phase 1Ages 1-21Nationwide Children's Hospital10US sites
9 states - A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK FusionMost sites in Ohio, Colorado and District of ColumbiaRecruitingEarly Phase 1Up to age 21Nationwide Children's Hospital9US sites
8 states - Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).Most sites in California, Georgia and IllinoisRecruitingPhase 2Ages 1-26BrainChild Bio6US sites
6 states - Lutathera for Treatment of Recurrent or Progressive High-Grade CNS TumorsMost sites in Ohio and PennsylvaniaRecruitingPhase 1/2Ages 4-39Nationwide Children's Hospital3US sites
2 states - rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMGMost sites in California, Illinois and MassachusettsRecruitingPhase 1Ages 12 Months-18Ann & Robert H Lurie Children's Hospital of Chicago3US sites
3 states - Atovaquone Combined With Radiation in Children With Malignant Brain TumorsOnly in GeorgiaRecruitingPhase 1Ages 2-25Emory University2US sites
- PEACH TRIAL- Precision Medicine and Adoptive Cellular TherapyMost sites in Florida and PennsylvaniaRecruitingPhase 1Ages 1-30University of Florida2US sites
2 states - C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)Only in TexasRecruitingPhase 1Ages 12 Months-25Baylor College of Medicine1US site
- CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young AdultsOnly in MinnesotaRecruitingPhase 1Ages 2-25OX2 Therapeutics1US site
- FUS Etoposide for DMGOnly in New YorkRecruitingPhase 1Ages 4-21Columbia University1US site
- International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and RepositoryOnly in OhioRecruitingChildren's Hospital Medical Center, Cincinnati1US site
- Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem GliomaOnly in District of ColumbiaRecruitingUp to age 21Children's National Research Institute1US site
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Who runs the Diffuse Intrinsic Pontine Glioma trials in the US, and what stage they are in
None of the 24 Diffuse Intrinsic Pontine Glioma trials with a US site is in Phase 3, the last stage before a company can ask the FDA for approval. Earlier Phase 1 or 2 tests of safety and dosing make up 21 of them. The remaining 3 have no drug phase, such as studies that follow people over time or test a device or a way of giving care. Companies run 3 of them, and universities, hospitals, foundations and government groups run 21. The sponsors with the most are Nationwide Children's Hospital (7), Children's National Research Institute (2) and University of Florida (2). The most recently listed one first appeared on ClinicalTrials.gov on July 2, 2026.
Diffuse Intrinsic Pontine Glioma trials in the US, state by state
All 24 Diffuse Intrinsic Pontine Glioma trials with a US site accept children under 18. Their open sites are in 28 states and Washington, DC, most often Ohio, Pennsylvania and District of Columbia. A trial counts once in each state where it has an open site, and some trials accept both children and adults.
Show the other 19 states
US hospitals running the most Diffuse Intrinsic Pontine Glioma trials
Centers that run trials for a rare condition often see more people with it than most clinics do, so this list can also help you find doctors who know Diffuse Intrinsic Pontine Glioma.
- Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania10 trials
- Nationwide Children's HospitalColumbus, Ohio10 trials
- Seattle Children's HospitalSeattle, Washington10 trials
- Children's National Medical CenterWashington D.C., District of Columbia9 trials
- Cincinnati Children's Hospital Medical CenterCincinnati, Ohio9 trials
- Children's Hospital ColoradoAurora, Colorado8 trials
- Texas Children's HospitalHouston, Texas8 trials
- Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois6 trials
- Dana-Farber Cancer InstituteBoston, Massachusetts6 trials
- Duke University Health SystemDurham, North Carolina5 trials
Help getting to a Diffuse Intrinsic Pontine Glioma trial far from home
Ask the study team whether the trial pays back travel, parking and hotel costs, because many sponsors do. The FDA's guidance on paying research volunteers says paying back these costs does not count as pressuring someone to join.
These nonprofits also help patients reach care, and each one sets its own rules.
- Mercy Medical Angels
- Pays for gas cards, ground rides and airline tickets anywhere in the US, and it lists clinical trials as a reason to travel. Household income at or below 300% of the federal poverty guidelines, and usually a trip of 50 miles or more each way.
- Air Charity Network
- Volunteer pilots in all 50 states fly patients for free in small private planes, and members also fly people taking part in clinical trials. You must be able to walk and sit upright for the flight, show financial need and have a backup plan if weather cancels it.
- Corporate Angel Network
- Puts cancer patients in empty seats on business jets for treatment, second opinions and clinical trials. Open to anyone with cancer who can walk and travel without medical help, and it does not check income.
- American Cancer Society Hope Lodge
- Offers a free place to stay at 31 Hope Lodge locations for people getting cancer treatment far from home. People facing cancer and their caregivers, when treatment is far from home.
- Ronald McDonald House
- Gives families a room near the hospital while a child gets care, through 394 House programs around the world. Families of a sick child, with rules set by each local chapter.
- Healthcare Hospitality Network
- Keeps a map of hospitality houses near hospitals, and most member houses charge little or nothing to patients and families. Each house sets its own rules, so check with the house near your study site.
Program details were checked on each program's website on October 24, 2026.
Questions about finding a Diffuse Intrinsic Pontine Glioma trial near you
Are there Diffuse Intrinsic Pontine Glioma clinical trials near me?
As of November 13, 2026, 31 Diffuse Intrinsic Pontine Glioma clinical trials are recruiting now and 10 are not yet recruiting. In the US, 24 of them have at least 1 open site, across 28 states and Washington, DC. Enter your ZIP code on this page to rank every one of them by the distance to its closest open site, with the sites shown on a map.
Which states have Diffuse Intrinsic Pontine Glioma clinical trial sites?
Recruiting Diffuse Intrinsic Pontine Glioma trials list open sites in 28 states and Washington, DC. Ohio, Pennsylvania and District of Columbia have the most, and the table on this page lists every state.
Are there Diffuse Intrinsic Pontine Glioma trials for children near me?
All 24 Diffuse Intrinsic Pontine Glioma trials with a US site accept children under 18. Their open sites are in 28 states and Washington, DC, most often Ohio, Pennsylvania and District of Columbia. Each trial sets its own age limits, so check the ages listed on a trial before you contact it.
Who pays for travel to a Diffuse Intrinsic Pontine Glioma clinical trial?
Many trial sponsors pay back travel, parking and hotel costs, so ask the study team before you rule out a far-away site. The FDA's guidance says paying back these costs does not count as pressuring someone to join. Charities such as Mercy Medical Angels and Air Charity Network can also help with rides and flights, and Corporate Angel Network flies cancer patients for free.
What if there is no Diffuse Intrinsic Pontine Glioma trial near me?
Some trials send staff to your home or use a local lab, so fewer visits happen at the study site. You can also sign up on this page to get an email when a Diffuse Intrinsic Pontine Glioma trial opens a new site or changes status.
How is the distance to a trial site measured?
Distances are straight-line miles from the center of your ZIP code to each study site's listed location, not driving distance. Your browser looks up the ZIP code's coordinates with a free map service, Zippopotam.us, and the ZIP code is never sent to or stored by Trial Friend.
FDA-approved for Diffuse Intrinsic Pontine Glioma: Modeyso (dordaviprone).
Clinical trials near you for related conditions
Source: ClinicalTrials.gov, trials with status Recruiting or Not yet recruiting. Refreshed every 6 hours; counts as of November 13, 2026. Sites that ClinicalTrials.gov lists as closed or withdrawn are left out. Children means the trial's age group includes people under 18.