Vanda Pharmaceuticals Inc.
Latest, March 26, 2026On March 26, 2026, the FDA issued its decision on Vanda's request for a hearing on the agency's proposal to refuse approval of tradipitant for gastroparesis. FDA, Federal Register
Vanda Pharmaceuticals Inc. works on 2 rare diseases tracked on Trial Friend, including Gastroparesis, Multiple Sclerosis, with 2 active clinical trials (1 recruiting) and 1 FDA-approved rare disease drug.
Vanda Pharmaceuticals is a Washington, DC drugmaker founded in 2003 that markets Hetlioz (tasimelteon), approved for nighttime sleep problems in Smith-Magenis syndrome as well as non-24-hour sleep-wake disorder, and its other medicines include Fanapt, Ponvory and Nereus, with Bysanti approved in February 2026. In gastroparesis, the FDA declined to approve Vanda's tradipitant in September 2024, and Vanda has challenged that outcome; the FDA later approved tradipitant, as Nereus, to prevent vomiting caused by motion.
Vanda Pharmaceuticals Inc. Drug Pipeline
Vanda Pharmaceuticals Inc. has 2 active clinical trials across 2 development stages, with 1 currently recruiting participants. Clinical trials advance through phases: Phase 1 tests safety in a small group, Phase 2 evaluates effectiveness and side effects, Phase 3 confirms benefit in a larger population, and Phase 4 monitors long-term safety after FDA approval.
Note: This pipeline counts the active and recruiting trials listed on this page, from ClinicalTrials.gov. For companies that work outside rare disease, we list only trials for rare diseases we track, so the company's full pipeline may be larger.
Vanda Pharmaceuticals Inc. Clinical Trials (2)
Active and recruiting clinical trials sponsored by Vanda Pharmaceuticals Inc., sourced live from ClinicalTrials.gov. Each trial card shows the study phase, current recruitment status, conditions under investigation, study locations, eligibility criteria, and a direct link to the full ClinicalTrials.gov record. You can also download a one-page PDF summary to share with your doctor.
Note: Recruitment statuses on ClinicalTrials.gov may not immediately reflect recent FDA decisions, sponsor announcements, or enrollment changes. Always confirm a trial's current status directly with the study coordinator.
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Vanda Pharmaceuticals Inc. FDA-Approved Drugs (1)
Medications developed or marketed by Vanda Pharmaceuticals Inc. that have received U.S. Food and Drug Administration approval. Drug data is sourced from the openFDA database and includes brand names, generic names, approval dates, and matched rare disease indications. Where a drug treats a condition covered by Trial Friend, the disease name links directly to that disease page.
| Drug Name | Brand Name | Rare Diseases | Approval Date |
|---|---|---|---|
| PONESIMOD Sphingosine 1-phosphate Receptor Modulator [EPC] | PONVORY oral | Mar 18, 2021 |
Vanda Pharmaceuticals Inc. Trial Locations
Vanda Pharmaceuticals Inc. clinical trials are running at 4 sites in 3 countries. Click any country to drill down by state, city, and individual research facility. Proximity to a trial site is one of the most important factors in deciding whether to participate.
Rare Disease Focus Areas (2)
Diseases targeted by Vanda Pharmaceuticals Inc.'s clinical trial and drug development programs
Gastroparesis is a condition in which the stomach empties food too slowly even though nothing is blocking it, causing early fullness, nausea, vomiting, bloating and upper belly pain. Diabetes is the m...
Multiple sclerosis is a chronic autoimmune disease where the immune system attacks the protective myelin sheath surrounding nerve fibers in the brain and spinal cord. This disrupts communication betwe...
Patient Resources
Organizations and resources related to Vanda Pharmaceuticals Inc.'s rare disease focus areas
Frequently Asked Questions About Vanda Pharmaceuticals Inc.
Common questions about Vanda Pharmaceuticals Inc.'s rare disease programs, clinical trials, and treatments.