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Allergy and immunology: rare disease drugs and conditions
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1 condition and 6 prescribing guides so far.
By specialty and condition
Each condition page compares its drugs side by side and lists FDA decisions, label changes and open trials.
Prescribing guides
The first 90 days from the prescriber's side, built from the current label, the drugmaker's program and one public insurer policy.
Hereditary angioedema (HAE)
Andembry (garadacimab-gxii)Loading Dose, Enrollment and PA CriteriaNo REMS; referral form to ANDEMBRY Connect by electronic form or fax, prior authorization, specialty pharmacy shipment, and injection training before the first self-injection.Dawnzera (donidalorsen)Dosing, Enrollment Form and PA CriteriaNo REMS; Patient Enrollment and Prescription Form by fax or an e-prescription, prior authorization, patient contact with the Ionis Every Step Specialty Pharmacy before it ships, and injection training before the first dose.Ekterly (sebetralstat)Dosing, CYP3A4 Rules and PA CriteriaNo REMS, no boxed warning, no contraindications and no baseline labs in the label; KalVista's enrollment path is the KalVista Cares Start Form, benefits investigation and prior authorization, then a specialty pharmacy.Firazyr (icatibant)Dosing, Generics and PA CriteriaNo REMS; prescription and Takeda Patient Support Start Form (online or fax), prior authorization, specialty pharmacy dispensing, and self-injection training before the first attack treated at home.Orladeyo (berotralstat)Dosing, Pellets, QTc, Interactions and PANo REMS; Start Form to Empower Patient Services (CareMed Specialty Pharmacy only), prior authorization with C1-INH function and C4 results, and a required pharmacist counseling call before the first shipment.Takhzyro (lanadelumab-flyo)Dosing by Age, Start Form and PA CriteriaNo REMS; Start Form (the prescription) by fax or online, prior authorization, specialty pharmacy dispensing, and injection training before the first self-injection.