Keros Therapeutics
Keros Therapeutics works on 3 rare diseases tracked on Trial Friend, including Duchenne Muscular Dystrophy, Myelofibrosis, Pulmonary Arterial Hypertension.
Keros Therapeutics is a clinical-stage biopharmaceutical company developing therapies for disorders linked to dysfunctional signaling of the transforming growth factor-beta (TGF-beta) family of proteins. The company's lead product candidate, rinvatercept, is in development for Duchenne muscular dystrophy and amyotrophic lateral sclerosis. Its most advanced product candidate, elritercept (KER-050), is in development for cytopenias including anemia and thrombocytopenia in patients with myelodysplastic syndromes and myelofibrosis, and is partnered with Takeda. Keros discontinued its PAH program (cibotercept/KER-012) in May 2025 following the failed TROPOS Phase 2 trial.
Active Clinical Trials
FDA-Approved Drugs
Rare Disease Focus Areas (3)
Diseases targeted by Keros Therapeutics's clinical trial and drug development programs
Duchenne muscular dystrophy is an X-linked genetic disorder causing progressive muscle weakness and degeneration, beginning in early childhood. The defective dystrophin protein normally protects muscl...
Myelofibrosis is a myeloproliferative neoplasm in which bone marrow develops scarring (fibrosis), leading to anemia, enlarged spleen, and abnormal blood cell counts. Most cases involve JAK2, CALR, or ...
Pulmonary arterial hypertension is a rare disease characterized by abnormally high blood pressure in the pulmonary arteries, causing progressive heart and lung damage. The disease involves vasoconstri...
Patient Resources
Organizations and resources related to Keros Therapeutics's rare disease focus areas
Frequently Asked Questions About Keros Therapeutics
Common questions about Keros Therapeutics's rare disease programs, clinical trials, and treatments.