Starting Voydeya (danicopan)Your first 90 days with paroxysmal nocturnal hemoglobinuria (PNH): the steps, the dates and who to call

How you take it

Tablets 3 times a day, at about the same times each day, with or without food. You keep getting your Ultomiris or Soliris infusions too.

Before your first dose

• Two kinds of vaccines, at least 2 weeks before your first dose: meningitis vaccines (meningococcal, which means the ACWY shot and the MenB shot) and a pneumonia vaccine (pneumococcal). Shots you had in the past may not be enough, so your doctor checks.
• If your doctor decides you cannot wait 2 weeks, the label says you get the vaccines as soon as possible and take antibiotics too.
• A blood test of your liver before your first dose, because Voydeya can raise liver enzymes.
• Your doctor gives you a Patient Safety Card. Keep it with you the whole time you take Voydeya and for 1 week after.
• Your insurance approves the medicine. Onco360, a specialty pharmacy, fills it and checks your vaccines with your doctor before it ships.
• Alexion OneSource, the drugmaker's support program, may help you find the vaccines and may help with costs. Its number is 1-888-765-4747.

The first 90 days

1. 4 weeks beforeVaccine plan made, with help finding the shots
2. 3 weeks beforeVaccines done, or scheduled
3. Before day 1Liver blood test before your first dose
4. Week beforeInsurance approval, then the pharmacy sets up delivery
5. Day 1First dose, then 2 more that day
6. After 4 weeksBlood count check, when your doctor may raise the dose
7. Day 31, then every 30 daysRefill, then about every 30 days
8. Week 12Where the trial measured results
9. Around 3 monthsLiver and cholesterol blood tests, when your doctor schedules them