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How you take it

A healthcare provider gives every dose. The first is a drip into a vein on day 1. Next comes 1 injection under the skin of your belly on days 2, 8, 15 and 22. From day 29 you get 2 or 3 injections every 4 weeks.

Before your first dose

• Meningitis vaccines (meningococcal, for groups A, C, W, Y and B) at least 2 weeks before your first dose. A vaccine you had in the past might not be enough, so your doctor checks.
• If your doctor decides you cannot wait 2 weeks, the label says you get the vaccines as soon as possible and take antibiotics too.
• The label also calls for a pneumonia vaccine (pneumococcal) on the schedule your doctor follows.
• Your doctor gives you a Patient Safety Card. Carry it the whole time you get Piasky and for 11 months after your last dose.
• If you take Soliris or Ultomiris now, the label says your first Piasky dose comes no sooner than your next dose of that medicine was due. Your doctor watches you for 30 days after the switch.
• You and your doctor's office each fill out a form for PiaSky Access Solutions, the drugmaker's support program. Its Case Managers answer at 877-436-3683.
• Your insurance approves the medicine. A specialty pharmacy checks your vaccines with your doctor's office before it sends the first dose.

The first 90 days

1. 3 weeks beforeVaccines done, or scheduled
2. Week beforeInsurance approval, then the pharmacy checks your vaccines with your doctor
3. Day 1First dose, by infusion
4. Day 2First injection under the skin
5. Days 8, 15, 22One injection on each of days 8, 15 and 22
6. Day 29, then every 28 daysYour every-4-weeks doses start, 2 or 3 injections each time
7. First 30 daysIf you switched from Soliris or Ultomiris, the 30-day watch for a reaction ends
8. About 12 weeksAfter about 12 weeks the medicine reaches a steady level in your blood