Starting Papzimeos (zopapogene imadenovec-drba)Your first 90 days with recurrent respiratory papillomatosis: the steps, the dates and who to call

How you take it

Four shots under the skin of the outer upper arm or thigh over 12 weeks. A healthcare professional gives each one, at the start and then 2, 6 and 12 weeks later.

Before your first dose

• Surgery to remove the growths in your airway that can be seen. This comes before your first shot.
• A place to get the shots that can store the medicine in a very cold freezer. Your ENT may need to work with another clinic or hospital.
• Your doctor's office sends the Papzimeos SUPPORT enrollment form. Precigen says a company it calls Biologics then contacts you for your signature.
• Your insurance approves the medicine. The clinic is asked to order each vial at least 2 weeks before the planned shot.
• Tell your doctor about all your medical conditions, and about a pregnancy, plans for one, or breastfeeding.

The first 90 days

1. Weeks beforeThe enrollment form is sent and your insurance is checked
2. 2 weeks before or moreThe clinic orders the first vial
3. Before dose 1Surgery to remove the growths that can be seen
4. Day 1Dose 1, an injection under the skin
5. Days afterThe injection site and how you feel
6. Day 15Second shot
7. Day 43Third shot. If growths can be seen, they are removed first
8. Day 85Fourth and last shot. If growths can be seen, they are removed first
9. Month 3 and onFollow-up and the 12-month mark