Starting Ofev (nintedanib)Your first 90 days with idiopathic pulmonary fibrosis (IPF): the steps, the dates and who to call

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Fill in with your doctor's office

First dose date

Doctor who prescribed it

Doctor's office phone

Specialty pharmacy name

Specialty pharmacy phone

Tell your doctor right away about:

Unexplained signs of a liver problem, such as yellowing of your skin or the whites of your eyes, dark or brown, tea-colored urine, pain on the upper right side of your stomach area, bleeding or bruising more easily than normal, feeling tired, or loss of appetite; symptoms of a heart problem, such as chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath; symptoms of a stroke, such as numbness or weakness on 1 side of your body, trouble talking, headache or dizziness; a pregnancy or a possible pregnancy. If you take too much Ofev, call your doctor or go to the nearest hospital emergency room right away.

Also tell your doctor's office about:

Diarrhea at the first signs, and nausea or vomiting that does not go away or gets worse
Unusual bleeding, bruising or wounds that do not heal
Pain or swelling in your stomach area
Foamy urine, swelling in your hands, arms, legs or feet, or sudden weight gain
Any new medicine or supplement, including blood thinners, aspirin and St. John's wort

CareConnect4Me (Boehringer Ingelheim)1-866-673-6366

Not listed for the phone line; Boehringer describes the program's health resource support as available 24/7

The drugmaker's support program, for questions about getting the medicine and paying for it. Answer calls from the specialty pharmacy; a missed call can delay your delivery.

Scan for your full plan, with every date added to your phone calendartrialfriend.com/p/ofev

How you take it

One capsule twice a day, about 12 hours apart, with food. Swallow it whole with a drink. Do not chew, crush or open it.

Before your first dose

A blood test of your liver, because Ofev can affect the liver.
A pregnancy test if you could become pregnant, because Ofev can harm an unborn baby. The label calls for highly effective birth control during treatment and for at least 3 months after the last dose.
A full medicine check. Some medicines and supplements, such as St. John's wort, change Ofev levels, and blood thinners matter too.
If you smoke, a talk with your doctor about stopping, because smoking lowers the amount of Ofev in your blood.
Your insurance approves the medicine. Some plans want generic nintedanib tried first. Boehringer Ingelheim, the drugmaker, runs a support program at 1-866-673-6366.
A specialty pharmacy delivers Ofev to your home.

The first 90 days

Before day 1Liver blood test before your first dose, and a pregnancy test if it applies to you
Week beforeInsurance approval, brand or generic
Days beforeSpecialty pharmacy delivery
Day 1First dose, 150mg twice a day
In the first 3 monthsLiver blood tests in the first 3 months, on the dates your doctor sets
Day 31, then every 30 daysRefill, when the 60-capsule bottle runs out
Day 90Three months in

Trial Friend, trialfriend.com. From the Ofev FDA label dated November 20, 2025 and the drugmaker's program, checked November 11, 2026. Not medical advice: Trial Friend is not a medical provider, and your doctor decides your dose and tests.