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Printable handout for patients starting Takhzyro. Write the details in by hand.Full plan

Starting Takhzyro (lanadelumab-flyo)Your first 90 days with hereditary angioedema (HAE): the steps, the dates and who to call

Trial Friendtrialfriend.com

How you take it

One shot under the skin every 2 weeks for most people 12 and older, from a prefilled syringe kept in the refrigerator. Young children get a smaller dose, given by an adult.

Before your first dose

  • Your doctor's office sends a Start Form to Takeda Patient Support, the drugmaker's support program. You sign it too.
  • A support specialist calls you within 2 to 4 days. Save 1-866-888-0660 in your phone so the call gets through.
  • Your insurance approves the medicine. Some plans want blood test results that confirm your type of HAE.
  • With commercial insurance, the Quick Start Program may send up to 2 months free while your insurance is checked.
  • A nurse or your care team shows you or a caregiver how to give the shot before the first one.

The first 90 days

  1. Before the first shotStart Form sent, then the insurance check
  2. 2 to 4 days laterA call from Takeda Patient Support
  3. Once approvedDelivery and injection training
  4. Day 1First dose
  5. Day 15, then every 14 daysSecond dose, then every 2 weeks
  6. Around day 29, then every 28 daysFirst refill, about 4 weeks in
  7. Day 70The medicine reaches a steady level in your blood
  8. Day 90Three months in
Trial Friend, trialfriend.com. From the Takhzyro FDA label dated September 18, 2026 and the drugmaker's program, checked November 10, 2026. Not medical advice: Trial Friend is not a medical provider, and your doctor decides your dose and tests.