Starting Palsonify (paltusotine)Your first 90 days with acromegaly: the steps, the dates and who to call

How you take it

Two tablets once a day with water, on an empty stomach, at least 6 hours after eating and at least 1 hour before your next meal.

Before your first dose

• Your past IGF-1 blood test results, from before you started any acromegaly medicine, for your insurance.
• Some insurers want you to have tried octreotide or lanreotide shots first. If you get one of these shots now, your doctor decides when your first Palsonify dose takes its place.
• A full medicine check. Heartburn pills called proton pump inhibitors, some other medicines, and medicines that slow the heart can all matter.
• Your doctor's office sends a form to CrinetiCARE, the drugmaker's support program, and you sign a consent page.
• Your insurance approves the medicine. If approval is slow, CrinetiCARE may send free medicine so you can start.
• A specialty pharmacy ships it to your home.

The first 90 days

1. 2 weeks beforeEnrollment form and the insurance request
2. Days beforeIf approval is slow, a quick start supply
3. Day 1First dose, two 20mg tablets with water
4. Weeks 2 to 4A blood test for IGF-1, and your dose may go up to 60mg
5. If raised to 60mgIf your dose goes up, you get a new bottle of 30mg tablets
6. Day 31, then every 30 daysRefill, then about every 30 days
7. Months 1 to 3Stomach side effects and heart rate
8. Day 90Three months in