Starting Orladeyo (berotralstat)Your first 90 days with hereditary angioedema (HAE): the steps, the dates and who to call

How you take it

One capsule or one packet of pellets once a day, with food. Never take a second dose in a day, and Orladeyo does not stop an attack that has started.

Before your first dose

• Your doctor's office sends a Start Form to Empower Patient Services, the drugmaker's pharmacy and support team.
• Your insurance approves the medicine. Some plans, such as Cigna, want blood test results that confirm your type of HAE.
• A pharmacist from Empower calls you before the first box can ship. Save 1-866-536-7693 so you answer that call.
• A full medicine check, including vitamins, herbal supplements and birth control pills.
• For a child under 12, a recent weight, because the pellet dose is set by weight.

The first 90 days

1. Before day 1Start Form to Empower
2. Week beforeInsurance approval, or Quick Start
3. Days beforeA pharmacist calls you, then the first box ships
4. Day 1First dose, once a day with food
5. Days 6 to 12Medicine levels settle in your blood
6. Around day 29, then every 28 daysFirst refill, then every 28 days
7. Weeks 4 to 8A check-in visit with your doctor
8. Day 90Three months in