Starting Lisraya (brepocitinib)Your first 90 days with dermatomyositis: the steps, the dates and who to call
Trial Friendtrialfriend.com
How you take it
One tablet once a day, with or without food.
Before your first dose
- A tuberculosis (TB) test, a hepatitis test, and blood tests of your blood counts, liver and kidneys.
- Your vaccines brought up to date, including the shingles vaccine. Ask which shots are live vaccines, because those are avoided right before and during treatment.
- A pregnancy test, if you could become pregnant, and a plan for birth control that lasts until 3 days after the last dose.
- Tell your doctor about any infections, smoking, cancer, heart problems, blood clots, stomach problems or diabetes.
- Your doctor's office sends a form to My Compass Support, the drugmaker's support program. A Patient Access Liaison then calls or texts you.
- Your insurance approves the medicine. A specialty pharmacy, Orsini or PANTHERx, calls to set up delivery to your home. Answer calls from numbers you do not know that week.
The first 90 days
- Weeks beforeTB test, hepatitis test and blood tests
- Weeks beforeVaccines brought up to date, including shingles
- 2 weeks beforeA welcome call or text from the support program
- Before day 1Pregnancy check, where it applies
- Days beforeThe specialty pharmacy calls
- Day 1First dose, one 30mg tablet
- Day 14Two weeks in
- Day 31, then every 30 daysRefill, then every 30 days
- About week 12Cholesterol blood test
Trial Friend, trialfriend.com. From the Lisraya FDA label dated August 27, 2026 and the drugmaker's program, checked November 9, 2026. Not medical advice: Trial Friend is not a medical provider, and your doctor decides your dose and tests.