Starting Enspryng (satralizumab-mwge)Your first 90 days with neuromyelitis optica spectrum disorder (NMOSD): the steps, the dates and who to call

How you take it

A shot under the skin of your belly or thigh. You get 3 starting shots 2 weeks apart, then 1 shot every 4 weeks. The first shot is given with your doctor's office guiding you. After training, you or a helper can give it at home if your doctor agrees.

Before your first dose

• A blood test for hepatitis B. The label says Enspryng is not given to people with an active hepatitis B infection.
• A check for tuberculosis (TB), including a test for TB hiding in your body without symptoms.
• Blood tests of your liver.
• Live vaccines at least 4 weeks before your first shot. Other vaccines at least 2 weeks before, if possible. Ask your doctor which ones you need.
• You and your doctor fill out the ENSPRYNG Start Form. A Patient Navigator then checks what your insurance covers.
• Your insurance approves the medicine. With private insurance, you may pay as little as $0.

The first 90 days

1. Before the first doseStart Form and the coverage check
2. Before the first doseHepatitis B, tuberculosis and liver tests
3. At least 4 weeks beforeLast day for live vaccines, 4 weeks before day 1
4. At least 2 weeks beforeOther vaccines, when possible
5. Once approvedApproval, then the first carton ships
6. Day 1Day 1: first shot, with your doctor's office guiding you
7. Within a day of each shotInjection reactions
8. Day 15Day 15: second starting shot
9. Day 29Day 29: third starting shot and a liver blood test
10. Day 29, then every 28 daysDay 29: third starting shot and a liver blood test
11. Weeks 4 to 8Day 29: third starting shot and a liver blood test
12. Day 57, then every 28 daysDay 57: shots every 4 weeks from now on
13. Week 8Day 57: shots every 4 weeks from now on
14. After month 3Liver tests every 3 months