Starting Elfabrio (pegunigalsidase alfa-iwxj)Your first 90 days with fabry disease: the steps, the dates and who to call

How you take it

An infusion into a vein every 2 weeks. The dose depends on your weight. The first few infusions are slow, and they can get shorter later if they go well.

Before your first dose

• Your doctor's office and you fill out one Start Form, which goes to Chiesi Total Care, the drugmaker's support program. Signing up for the program is your choice.
• Your insurance approves the medicine. The program can help your doctor's office if the plan says no.
• Your first infusions are at a clinic or doctor's office, where staff have emergency equipment ready in case of a serious allergic reaction.
• You may get allergy or fever medicines, or a steroid, before each infusion. If you had these before another Fabry infusion, tell your doctor.
• If you are switching from Fabrazyme or another Fabry infusion, bring your last infusion date, your dose and how long your infusions took.

The first 90 days

1. Before the first infusionFill out the Start Form, insurance check
2. Once approvedApproval, then booking the infusion
3. Day 1First infusion, at the slow starting rate
4. Days 1 to 2Days 1 to 2: watch for reactions for 24 hours after the infusion
5. Day 15Infusion 2, same slow rate
6. Day 29Infusion 3, and the first refill
7. Day 43Infusion 4
8. Day 57Day 57: earliest day an infusion can be 30 minutes shorter
9. Day 71Infusion 6, the last at the starting rate
10. Day 85Infusion 7