Starting Ekterly (sebetralstat)Your first 90 days with hereditary angioedema (HAE): the steps, the dates and who to call

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Fill in with your doctor's office

First dose date

Doctor who prescribed it

Doctor's office phone

Specialty pharmacy name

Specialty pharmacy phone

MedlinePlus says to seek immediate medical attention for:

Difficulty breathing due to swelling. MedlinePlus calls swelling of the airway a life-threatening emergency. The Ekterly label says severe throat attacks were not treated in its main trial, and it gives no separate instructions for a throat attack.

Also tell your doctor's office about:

Taking too much Ekterly; the Patient Information says to call your prescriber or Poison Help at 1-800-222-1222, or go to the nearest hospital emergency room right away
An attack that has not eased, has gotten worse or has come back after the doses the label allows
Headache, the most common side effect, if you want medical advice about it
Every medicine, vitamin and herbal supplement you take, and each new medicine you get
Liver problems, a pregnancy, or plans to breastfeed

KalVista Cares Patient Support Program (KalVista)1-844-432-3322

Monday to Friday, 8:30 am to 8 pm ET

The drugmaker's support program, for questions about getting the medicine and paying for it. Answer calls from the specialty pharmacy; a missed call can delay your delivery.

Scan for your full plan, with every date added to your phone calendartrialfriend.com/p/ekterly

How you take it

The label dose is 2 tablets by mouth at the earliest sign of an attack. The label allows 2 more tablets at least 3 hours later, if needed. The label's limit is 4 tablets in any 24 hours. Your doctor may set 1 tablet per dose instead.

Before your first dose

Your doctor's office sends a Start Form to KalVista Cares, the drugmaker's support team.
Once KalVista Cares confirms you are eligible, a Care Manager calls you within 1 business day. The KalVista Cares number is 1-844-432-3322.
Your insurance approves the medicine. Some plans, such as Cigna, want blood test results that confirm your type of HAE.
A full medicine check, including vitamins and herbal supplements, because some medicines change the dose or should not be taken with Ekterly.
Your doctor hears about any liver problems, because they can change the dose.

The first 90 days

Before day 1Start Form to KalVista Cares
After enrollmentA Care Manager calls you
While coverage is decidedInsurance approval, or QuickStart
Day 1First carton in hand
At an attackWhat the label says to do when an attack starts
At least 3 hours laterAt least 3 hours later, what the label says about a second dose
After any useRefills depend on how many attacks you treat
In one planOne plan's limit for home delivery
Day 90Three months in

Trial Friend, trialfriend.com. From the Ekterly FDA label dated April 1, 2026 and the drugmaker's program, checked November 11, 2026. Not medical advice: Trial Friend is not a medical provider, and your doctor decides your dose and tests.