Starting Attruby (acoramidis)Your first 90 days with ATTR amyloidosis with cardiomyopathy: the steps, the dates and who to call

How you take it

Two tablets twice a day, morning and evening, swallowed whole, with or without food.

Before your first dose

• Proof of your diagnosis for your insurance: a heart scan, a tissue sample (biopsy) or a genetic test, plus a heart ultrasound or MRI showing the heart is affected.
• A full medicine check. Some medicines can lower Attruby levels, and Attruby can raise levels of some others.
• If you take tafamidis or a gene-silencing shot or infusion, ask your heart doctor what this means for your current treatment. Some insurers will not pay for both.
• Your heart doctor's office sends a start form to ForgingBridges, the drugmaker's support program, and you sign a consent form.
• Your insurance approves the medicine. New patients may get a free first month, and more free supply while insurance is delayed.
• A specialty pharmacy or ForgingBridges calls you. Answer calls from numbers you do not know, including 800 numbers.

The first 90 days

1. 2 weeks beforeStart Form, consent and the insurance request
2. Days beforeThe pharmacy or ForgingBridges calls
3. Day 1First dose, 2 tablets, then 2 more that evening
4. Weeks 1 to 4Your kidney blood test may change a little, which is expected
5. Day 29, then every 28 daysRefill, then about every 28 days
6. Month 2If you started on free medicine, check that insurance will take over
7. Day 90Three months in